2-Amino-3-carboxymuconic semialdehyde

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2-Amino-3-carboxymuconic semialdehyde
2-Amino-3-carboxymuconic semialdehyde.png
Identifiers
CAS number 16597-58-3
PubChem 5280673
ChemSpider 7822292 YesY
ChEBI CHEBI:994 YesY
Jmol-3D images Image 1
Properties
Molecular formula C7H7NO5
Molar mass 185.13 g/mol
Density 1.527 g/mL
Boiling point 389 °C (732 °F; 662 K)
Hazards
Flash point 189 °C (372 °F; 462 K)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
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Infobox references

2-Amino-3-carboxymuconic semialdehyde is an intermediate in the metabolism of tryptophan in the tryptophan-niacin catabolic pathway. Quinolinate is a neurotoxin formed nonenzymatically from 2-amino-3-carboxymuconic semialdehyde in mammalian tissues. 2-Amino-3-carboxymuconic semialdehyde is enzymatically converted to 2-aminomuconate via 2-aminomuconic semialdehyde.