The 2d Combat Cargo Group was organized at Syracuse Army Air Base, New York, and trained with C-46 and C-47 aircraft. It moved to Baer Field, Indiana for overseas processing. Its operational squadrons were the 5th,6th, 7th, and 8th Combat Cargo Squadrons. The group moved to the Southwest Pacific, arriving in November 1944, and assigned to Fifth Air Force. It initially operated from Biak Island, Papua New Guinea to fly passengers and cargo to US bases in Australia, New Guinea, the Admiralties, and the Philippines. The group also dropped supplies to US and guerrilla forces in the Philippines. The group moved to Leyte in May 1945. Maintaining its flights in the Southwest Pacific, it also transported personnel and supplies to the Ryukyus, and evacuated casualties on return flights. The 2d moved to Okinawa in August 1945. While there it transported personnel and equipment of the occupation forces to Japan and ferried liberated prisoners of war back to the Philippines. The group moved to Japan in September 1945 and served with the occupation forces until it was inactivated on 15 January 1946. It was disbanded on 8 October 1948.
The group was reconstituted on 31 July 1985 and redesignated as the 362d Military Airlift Group, It was not active under this designation, but was redesignated as the 362d Airlift Support Group and activated on 1 April 1992 at Rhein-Main Air Base, Germany. It was inactivated circa1 July 1994. It has since been converted to provisional status as the 362d Air Expeditionary Group and assigned to Air Mobility Command to activate as needed.