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Initially Kettering and Deeds were co-workers at National Cash Register Company (NCR). Kettering and Deeds had a lifelong professional relationship and friendship.
In 1904, Deeds hired Kettering at NCR to motorize the cash register.
Around 1908, Deeds asked for help with a car he was building from a kit. Working in one of Deeds' barns with spare-time help from William A. Chryst and other NCR friends, Kettering developed a high-energy spark ignition system to replace the weak-spark model supplied with the kit. Leaving NCR in 1909, Kettering focused on final development of this ignition set and demonstrations were favorably received. In 1909, when Henry Leland of Cadillac ordered 5,000 ignition sets, Deeds and Kettering formed the Dayton Engineering Laboratories company. The ignition system was introduced on the 1910 Cadillac.
In 1911, Kettering invented and filed for U.S. Patent 1,150,523 for the first useful electric starter, adapted from a cash register motor. The starters were first installed by Cadillac on production models in 1912.
In 1912, the NCR company was found guilty of violating the Sherman Antitrust Act. Deeds and 27 other NCR executives and managers were convicted for illegal anti-competitive sales practices and were sentenced to one year of imprisonment. Their convictions were unpopular with the public due to their efforts to help those affected by the Dayton floods of 1913, but efforts to have them pardoned by President Woodrow Wilson were unsuccessful. However, their convictions were overturned on appeal in 1915 on the grounds that important defense evidence should have been admitted.
In 1915, Deeds left NCR to devote himself full-time to Delco.
At the time, one of Kettering's widely known inventions was the Delco-Light, a small internal combustion generator with battery intended to provide a source of electric illumination and mechanical power to rural residents (mostly farmers) who were not yet connected to the nascent electrical grid system.
The Delco brand name was associated with original production units of the company such as Delco Light, Delco Products, Delco Moraine and others.
During World War I, the Delco plant in Moraine, Ohio was expanded to manufacture the De Havilland DH.4 bomber, the only American-built airplane to see action in World War I. More than 3,000 were built in Moraine for the Dayton-Wright Airplane Company. Delco was also one of those that produced the Liberty engine.
In 1918, General Motors (GM) acquired the United Motors Company which had been formed several years earlier by William C Durant to house several prominent parts manufacturers, including Delco, Dayton-Wright, and the Dayton Metal Products Company. All of these latter companies were associated with Charles Kettering, Edward A. Deeds, and Harold E. Talbott.
Kettering became vice president of General Motors Research Corporation in 1920. He held the position as head of research for GM for 27 years.
In 1930 Delco Products researched and developed a new type of auto carburetion system called the Cold Carburetion System which was a cross of the standard carburetor of that era and the future fuel injection system. While Delco Products promised a lot with their invention, it never became an option on GM autos either as production or an add on. 
In 1936, Delco began producing the first dashboard-installed car radios. By the early 1970s, Delco had become a major supplier of automotive electronics equipment. Based in Kokomo, Indiana, Delco Electronics employed more than 30,000 at its peak.
In 1962, GM created the General Motors Research Laboratories, based in Santa Barbara, California, to conduct research and development activities on defense systems. This organization was eventually merged into Delco Electronics and renamed Delco Systems Operations.
In 1974, Donald J. Atwood Jr. was appointed as General Manager. The division was transformed in the following years as it grew to meet the needs of General Motors for engine and powertrain control modules to meet the US government's strict 1981 clean air act and other improved vehicle safety items including anti-skid brake system controllers and inflatable restraint (air-bag) systems.
In 1993, Gary W Dickinson was appointed CEO of Delco Electronics. Gary Dickinson used Delco Electronics' involvement in the Development of electronics for GM auto racing as major promotional opportunity sponsoring an Indy 500 team and the Indy 500 Festival Parade from 1993 to 1997.
In 1997, all of the aerospace and defense businesses of Hughes Electronics (Hughes Aircraft and Delco Systems Operations) were merged with Raytheon, the Hughes Network Systems portion of Hughes Communications became Direct TV, and the commercial portion of Delco Electronics was transferred to GM's Delphi Automotive business.
On May 28, 1999, Delphi became a separate publicly traded company, and continued to use the Delco Electronics name for several of its subsidiaries through approximately 2004.
Although Delco Electronics no longer exists as an operating company, GM still retains rights to the Delco name and uses it for some of its subsidiaries including the ACDelco parts division.
- Sloan, Alfred P. My Years With General Motors, p.249.
- G.N. Georgano, Cars: Early and Vintage, 1886-1930. (London: Grange-Universal, 1985)
- "Cold Gas Promises to Increase Power of Auto" Popular Mechanics Monthly, July 1930