Diiodohydroxyquinoline
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(Redirected from Yodoxin)
| Diiodohydroxyquinoline | |
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5,7-diiodoquinolin-8-ol |
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| Identifiers | |
| CAS number | 83-73-8  |
| PubChem | 3728 |
| KEGG | D00581 |
| MeSH | Iodoquinol |
| ChEMBL | CHEMBL86754  |
| Jmol-3D images | Image 1 |
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| Properties | |
| Molecular formula | C9H5I2NO |
| Molar mass | 396.951 |
 (verify) (what is:  / ?)Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references | |
Diiodohydroxyquinoline (INN) or iodoquinol (USAN), widely known by the trade name Diodoquin, is a quinoline derivative which can be used in the treatment of amoebiasis.[1]
Iodoquinol is poorly absorbed from the gastrointestinal tract and is amebicidal at the site of infection.[2] It acts by chelating ferrous ions essential for metabolism.[3]
In the United States this medicine is sold under the names Diquinol, Yodoquinol, and Yodoxin.[4] Yodoxin is available in 210- and 650-mg oral tablet form.[5]
Susceptibility of Dientamoeba fragilis has been measured.[6]
[edit] References
- ^ Ghaskadbi S, Vaidya VG (March 1989). "In vivo antimutagenic effect of ascorbic acid against mutagenicity of the common antiamebic drug diiodohydroxyquinoline". Mutat. Res. 222 (3): 219–22. doi:10.1016/0165-1218(89)90137-7. PMID 2493578.
- ^ http://www.drugs.com/mmx/iodoquinol.html
- ^ http://web.gideononline.com/web/therapy/index.php?type=drugs&code=20130&view=General
- ^ http://www.drugs.com/cons/yodoxin.html
- ^ http://www.walgreens.com/library/finddrug/druginfo.html?particularDrug=Yodoxin&searchChar=Y
- ^ Chan FT, Guan MX, Mackenzie AM, Diaz-Mitoma F (May 1994). "Susceptibility testing of Dientamoeba fragilis ATCC 30948 with iodoquinol, paromomycin, tetracycline, and metronidazole". Antimicrob. Agents Chemother. 38 (5): 1157–60. PMC 188168. PMID 8067755. http://aac.asm.org/cgi/pmidlookup?view=long&pmid=8067755.
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