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restored content, please discuss at TALK. Deletion of over 50 new systematic reviews is unjustified. Edit the section in question not the whole article.
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<div style="float:right; clear:both; margin:1em 0 1em 1em; background:#fff; border-collapse:collapse; border: #aaa 1px solid; font-size:0.9em; text-align:center; width:15em; padding:0.5em"><div style="font-size:1.1em">'''[[Chiropractic|Chiropractic medicine<br>]]'''</div>
{{Interventions infobox
----
| Name = Chiropractic manipulation
[[Daniel David Palmer|Daniel David Palmer (founder)]]
| Image = Chiropractic_spinal_adjustment.jpg
| Caption = A chiropractor performs spinal manipulative therapy
| ICD10 = {{ICD10PCS|9|9}}
| ICD9 =
| MeshID = D026882
| OPS301 =
| OtherCodes =
| HCPCSlevel2 =
}}
{{Quote box|quote= Chiropractic: from [[Greek language|Greek]] ''chiro-'' χειρο- "hand-" <br/> + ''praktikós'' πρακτικός "concerned with action"|source=([[OED]])}}
{{Alternative medical systems
|image = [[Image:Chiropractic5.JPG|200px|alt=Pastiche of man thinking and writing; the ribs, vertebrae, and hip bones of a human skeleton; a hand holding another; and Leonardo's famous drawing of a man in square and circle]]
|caption =
}}
'''Chiropractic''' is a form of [[complementary and alternative medicine]]<ref name=Chapman-Smith/> concerned with the diagnosis, treatment and prevention of disorders of the neuromusculoskeletal system and the effects of these disorders on general health.<ref name=WHO-guidelines/> Chiropractors primarily practice [[manual therapy]], with an emphasis on [[Spinal manipulation|manipulation of the spine]]. They are most prevalent in the United States, Canada, Australia and parts of Europe.<ref name=global-strategy>{{cite web|url=http://chiropracticdiplomatic.com/strategies/global_strategy.pdf|format=PDF|title=Global professional strategy for chiropractic|author=Tetrault M|publisher=Chiropractic Diplomatic Corps|year=2004|accessdate=2008-04-18 }}</ref>
Most people who seek chiropractic care do so for [[low back pain]].<ref name=Lawrence-Meeker/>


1895 · [[Davenport, Iowa|Davenport, USA]]
Chiropractic was founded in 1895 in Davenport, United States, by magnetic healer [[Daniel David Palmer|D.D. Palmer]] who posited that dysfunctional spinal joints dubbed [[vertebral subluxations]] was responsible for disease by interfering with [[innate intelligence]], the body's natural healing mechanism. Early graduates of Palmer's chiropractic rejected his "straight" monocausal view that all disease originated from the spine and opened competing schools which incorporated mainstream diagnostic approaches which incorporated spinal manipulations with other adjunctive forms of therapy such as [[massage]] and [[exercise]].<ref name=Martin/><ref name=Kaptchuk-Eisenberg/>


[[Chiropractic education|D.C. MSc.Chiro, MTech.Chiro]]
The [[scientific consensus]] is that chiropractic may be on a par with other manual therapies for some [[Human musculoskeletal system|musculoskeletal]] conditions such as lower back pain, but that there is no credible evidence or mechanism for effects on other conditions, and some evidence of severe adverse effects from cervical vertebral manipulation.<ref name=Trick-or-Treatment /> The ideas of innate intelligence and the chiropractic subluxation are regarded as [[pseudoscience]].<ref name=Ernst-eval/>
[[Image:The chiropractic symbol big.jpg|160px]]
[[World Federation of Chiropractic]]


[[Chiropractic schools|Schools]] · [[CCEI|Accreditation]]
==Conceptual basis==
</div>
For most of its existence, chiropractic has been sustained by [[Pseudoscience|pseudoscientific]] ideas such as subluxation and innate intelligence<ref name=History-Primer2/> which are not based on solid science.<ref name=Ernst-eval/> Some chiropractors have been criticized for having an anti-immunization stance, despite the consensus of [[public health]] professionals on the benefits of [[vaccination]],<ref name=Busse/> which has led to negative impacts on both public vaccination and mainstream acceptance of chiropractic.<ref name=Campbell/> The [[American Medical Association]] called chiropractic an "unscientific cult"<ref name=Chiro-PH/> and boycotted it until losing an [[Wilk v. American Medical Association|antitrust case in 1987]].<ref name=Cooper/> Chiropractic is said to have developed a strong political base and to have sustained demand for services; researchers Cooper and McKee report that it has gained more legitimacy and greater acceptance among [[physician]]s and [[health plan]]s in the U.S. for the treatment of some musculoskeletal conditions<ref name=Cooper/> and the principles of [[evidence-based medicine]] have been used to review research studies and generate [[Medical guideline|practice guidelines]].<ref name=Villanueva-Russell>{{cite journal|journal= [[Soc Sci Med]]|year=2005|volume=60|issue=3|pages=545–61|title= Evidence-based medicine and its implications for the profession of chiropractic|author= Villanueva-Russell Y|doi=10.1016/j.socscimed.2004.05.017|pmid=15550303}}</ref> Traditional (or ''straight'') chiropractic still assumes that a [[vertebral subluxation]] interferes with the body's "[[innate intelligence]]",<ref name=History-PPC/> a [[vitalistic]] notion ridiculed by the scientific and healthcare communities.<ref name=Keating-subluxation/> Other chiropractors want to separate themselves from the traditional vitalistic concept of innate intelligence<ref name=Kaptchuk-Eisenberg/>{{spaced ndash}}John W Reggars wrote in 2011 that chiropractic was at a crossroads, and that in order to progress it would need to embrace science; in his view, the promotion of chiropractic as a cure-all was both "misguided and irrational".<ref name="Reggars2011">{{cite doi|10.1186/2045-709X-19-11}}</ref>
</br>
'''Chiropractic''' is health care profession concerned with the structural diagnosis, treatment and prevention of disorders of the neuromusculoskeletal system and the effects of these disorders on general health. There is an emphasis on manual and manipulative therapy and its role in joint dysfunction/subluxation . Currently, chiropractic medicine is regulated and practiced in over 100 countries, however chiropractors are most prevalent in [[North America]], [[Australia]] and parts of [[Europe]].<ref name=WHO-guidelines>{{cite journal |author= World Health Organization|year=2005|title= WHO guidelines on basic training and safety in chiropractic|url=http://www.who.int/medicines/areas/traditional/Chiro-Guidelines.pdf|format=PDF|isbn= 92-4-159371-7|accessdate=2008-02-29}}</ref> The majority of mainstream health care and governmental organizations classify chiropractic as traditional/complementary alternative medicine<ref name=Chapman-Smith>{{cite book|author= Chapman-Smith DA, Cleveland CS III|chapter= International status, standards, and education of the chiropractic profession|pages=111–34|title= Principles and Practice of Chiropractic|edition=3rd|editor= Haldeman S, Dagenais S, Budgell B ''et al.'' (eds.)|publisher=McGraw-Hill|year=2005|isbn=0-07-137534-1}}</ref> Most people who seek chiropractic care do so for primarily for [[low back pain]] and other neuromusculoskeletal complaints.<ref name=Lawrence-Meeker>{{cite journal|journal=Chiropr Osteopat|year=2007|volume=15|title=Chiropractic and CAM Utilization: A Descriptive Review|author= Lawrence DJ, Meeker WC|doi=10.1186/1746-1340-15-2|pmid=17241465|url=http://chiroandosteo.com/content/15/1/2|page=2|pmc=1784103|issue=1}}</ref>


Chiropractic was founded in 1895 by [[Magnet therapy|magnetic healer]], [[Daniel David Palmer|D.D. Palmer]], in [[Davenport, Iowa|Davenport, Iowa, United States]]. Chiropractic theory on spinal joint dysfunction/subluxation and its putative role in non-musculoskeletal disease has been a source of controversy since its inception in 1895. The controversy is due in part to chiropractic's [[vitalism|vitalistic]] and [[metaphysics|metaphysical]] origins, and use of terminology that is not always amenable to [[scientific method|scientific investigation]]. Far reaching claims and lack of scientific evidence supporting spinal joint dysfunction/subluxation as the sole cause of disease has led to a critical evaluation of a central tenet of chiropractic and the appropriateness of the profession's role in treating a broad spectrum of disorders that are unrelated to the neuromusculoskeletal system.<ref name="How profession? podiatry">Murphy D.R., Schneider M.J., Seaman D.R., Perle S.M., Nelson C.F., http://www.ncbi.nlm.nih.gov/pubmed/18759966</ref> Although there is external and internal debate within the chiropractic profession regarding the clinical significance of joint dysfunction/subluxation,<ref name="The prevalence of the term subluxation in North American English-Language Doctor of chiropractic programs">Mirtz T.A., Perle S.M. http://www.ncbi.nlm.nih.gov/pubmed/21682859</ref> the manipulable lesion remains inextricably linked to the profession as basis for spinal manipulation.<ref name="Henderson 2012 632–642">{{cite journal|last=Henderson|first=C.N.R|journal=Journal of Electromyography and Kinesiology|year=2012|month=October|volume=22|issue=5|pages=632–642|accessdate=27 January 2013}}</ref>
{| style="float:right; border:2px solid; background:#f4f4f4; margin-left:0.4em;"
|+ '''Two chiropractic belief system constructs'''
! The testable principle
! &nbsp;
! The untestable metaphor
|-
|align=center| [[Chiropractic adjustment]]
|
|align=center| [[Universal Intelligence]]
|-
|align=center| ↓
|
|align=center| ↓
|-
|align=center| Restoration of structural integrity
|
|align=center| [[Innate intelligence]]
|-
|align=center| ↓
|
|align=center| ↓
|-
|align=center| Improvement of health status
|
|align=center| [[Human physiology|Body physiology]]
|-
| &nbsp;
|-
| '''''Materialistic:'''''
| &nbsp;&nbsp;&nbsp;
| '''''Vitalistic:'''''
|-
| — Operational definitions possible
|
| — Origin of holism in chiropractic
|-
| — Lends itself to scientific inquiry
|
| — Cannot be proven or disproven
|-
| style="text-align:center;" colspan="3"| ''Taken from Mootz & Phillips 1997''<ref name=Chiro-Beliefs/>
|}
Chiropractic's early philosophy was rooted in [[vitalism]], [[spirituality|spiritual inspiration]] and [[rationalism]]. A philosophy based on [[deductive reasoning|deduction]] from [[dogma|irrefutable doctrine]] helped distinguish chiropractic from medicine, provided it with legal and political defenses against claims of practicing medicine without a license, and allowed chiropractors to establish themselves as an autonomous profession. This "straight" philosophy, taught to generations of chiropractors, rejects the [[Inference|inferential reasoning]] of the [[scientific method]],<ref name=Keating05/> and relies on deductions from [[vitalistic]] first principles rather than on the [[materialism]] of science.<ref name=Chiro-Beliefs/>


Manual and conservative therapies commonly used by chiropractors are effective for the treatment of [[low back pain]],<ref name=Cochrane-2011>{{cite journal|journal= [[Cochrane Database Syst Rev]]|year=2011|issue=2|pages=CD008112|title= Spinal manipulative therapy for chronic low-back pain|author= Rubinstein SM, van Middelkoop M, Assendelft WJ, de Boer MR, van Tulder MW|doi=10.1002/14651858.CD008112.pub2|pmid=21328304|volume=|editor1-last= Rubinstein|editor1-first= Sidney M}}</ref><ref name=Dagenais-2010/> and might also be effective for the treatment of [[Lumbar vertebrae|lumbar]] [[spinal disc herniation|disc herniation]] with [[radiculopathy]],<ref name="Leininger B, Bronfort G, Evans R, Reiter T 2011 105–25">{{cite journal|journal= Phys Med Rehabil Clin N Am|year=2011|volume=22|issue=1|pages=105–25|title= Spinal manipulation or mobilization for radiculopathy: a systematic review|author= Leininger B, Bronfort G, Evans R, Reiter T|pmid=21292148|doi=10.1016/j.pmr.2010.11.002}}</ref><ref name="Hahne AJ, Ford JJ, McMeeken JM 2010 E488–504">{{cite journal|journal= Spine|year=2010|volume=35|issue=11|pages=E488–504|title= Conservative management of lumbar disc herniation with associated radiculopathy: a systematic review|author= Hahne AJ, Ford JJ, McMeeken JM|pmid=20421859|doi=10.1097/BRS.0b013e3181cc3f56}}</ref> neck pain,<ref name="Gross A, Miller J, D'Sylva J, Burnie SJ, Goldsmith CH, Graham N, Haines T, Brønfort G, Hoving JL 2010 315–333">{{cite journal|journal= Manual Therapy|year= 2010|volume=15|issue=4|pages=315–333|title= Manipulation or mobilisation for neck pain: a Cochrane Review|author= Gross A, Miller J, D'Sylva J, Burnie SJ, Goldsmith CH, Graham N, Haines T, Brønfort G, Hoving JL|pmid=20510644|doi= 10.1016/j.math.2010.04.002 }}</ref> some forms of headache,<ref name="Chaibi A, Tuchin PJ, Russell MB 2011">{{cite journal|journal= J Headache Pain|year=2011|volume= 12|issue= 2|pages= 127–33|title= Manual therapies for migraine: a systematic review|author= Chaibi A, Tuchin PJ, Russell MB|pmid=21298314|doi=10.1007/s10194-011-0296-6|pmc=3072494}}</ref><ref name="Bronfort G, Nilsson N, Haas M et al. 2004 CD001878">{{cite journal|journal= Cochrane Database Syst Rev|year=2004|issue=3|pages=CD001878|title= Non-invasive physical treatments for chronic/recurrent headache|author= Bronfort G, Nilsson N, Haas M ''et al.''|doi=10.1002/14651858.CD001878.pub2|pmid=15266458|editor1-last= Brønfort|editor1-first= Gert}}</ref> and some extremity joint conditions.<ref name="Brantingham JW, Globe G, Pollard H, Hicks M, Korporaal C, Hoskins W 2009 53–71">{{cite journal|author= Brantingham JW, Globe G, Pollard H, Hicks M, Korporaal C, Hoskins W|title= Manipulative therapy for lower extremity conditions: expansion of literature review|journal= J Manipulative Physiol Ther|volume=32|issue=1|pages=53–71|year=2009|pmid=19121464|doi=10.1016/j.jmpt.2008.09.013}}</ref><ref name="pmid21109059">{{Cite pmid|21109059}}</ref> There is insufficient evidence or known mechanisms for effects of chiropractic manipulation on non-musculoskeletal conditions.<ref name=Trick-or-Treatment>{{cite book|pages=145–90|chapter=The truth about chiropractic therapy|title=Trick or Treatment: The Undeniable Facts about Alternative Medicine|author=Singh S, Ernst E|year=2008|publisher=W.W. Norton|isbn=978-0-393-06661-6 }}</ref> The efficacy and cost-effectiveness of maintenance chiropractic care are unknown. <ref name=Leboeuf-Yde-C>{{cite journal|journal=Chiropr Osteopat|year=2008|volume=16|page=3|title=Maintenance care in chiropractic – what do we know?|author=Leboeuf-Yde C, Hestbæk L|doi=10.1186/1746-1340-16-3|pmid=18466623|url=http://chiroandosteo.com/content/16/1/3|pmc=2396648|issue=1}}</ref> A 2011 study, however, demonstrated that maintenance spinal manipulative therapy is effective for the treatment of chronic nonspecific low back [[pain]].<ref name="Senna 2011 1427–37">{{cite journal|last=Senna|first=MK|coauthors=Machaly SA.|title=SA.|journal=Spine|year=2011|month=Aug|pages=1427–37.|doi=10.1097/BRS.0b013e3181f5dfe0.|accessdate=26 January 2013}}</ref> There has been considerable debate over the safety of the core clinical act of chiropractors: spinal manipulation, particularly with the [[cervical spine]].<ref name=Ernst-adverse>{{cite journal|pmid=17606755|doi=10.1258/jrsm.100.7.330|laysummary=http://www.medicalnewstoday.com/articles/75754.php|laysource=Med News Today|laydate=2 July 2007|year=2007|month=Jul|last1=Ernst|first1=E|title=Adverse effects of spinal manipulation: a systematic review|volume=100|issue=7|pages=330–8|issn=0141-0768|journal=Journal of the Royal Society of Medicine|pmc=1905885}}</ref> Although serious injuries and fatal consequences can occur and may be under-reported,<ref name=Ernst-death/> these are generally considered to be rare when spinal manipulation is employed skillfully and appropriately.<ref name=WHO-guidelines/>
However, most practitioners currently accept the importance of scientific research into chiropractic,<ref name=Keating05>{{cite book|author= Keating JC Jr|chapter= Philosophy in chiropractic|pages=77–98|title= Principles and Practice of Chiropractic|edition=3rd|editor= Haldeman S, Dagenais S, Budgell B ''et al.'' (eds.)|publisher=[[McGraw-Hill]]|year=2005|isbn=0-07-137534-1}}</ref> and most practitioners are "mixers" who attempt to combine the materialistic reductionism of science with the metaphysics of their predecessors and with the [[Holistic medicine|holistic paradigm of wellness]];<ref name=Chiro-Beliefs/> a 2008 commentary proposed that chiropractic actively divorce itself from the straight philosophy as part of a campaign to eliminate [[Testability|untestable]] dogma and engage in critical thinking and evidence-based research.<ref name=Murphy-pod/>


Although a wide diversity of ideas currently exists among chiropractors,<ref name=Keating05/> they share the belief that the [[Vertebral column|spine]] and health are related in a fundamental way, and that this relationship is mediated through the nervous system.<ref>{{cite book|author= Gay RE, Nelson CF|chapter= Chiropractic philosophy|chapterurl=http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=altrehab.section.336|editor= Wainapel SF, Fast A (eds.)|title= Alternative Medicine and Rehabilitation: a Guide for Practitioners|year=2003|isbn=1-888799-66-8|location= New York|publisher= [[Demos Medical Publishing]]}}</ref> Chiropractors examine the [[biomechanics]], structure and function of the spine, along with its effects on the [[musculoskeletal]] and [[nervous system]]s and what they believe to be its role in health and disease.<ref name=ACA-history>{{cite web|title= History of chiropractic care|author= [[American Chiropractic Association]]|accessdate=2008-02-21|url=http://acatoday.org/level2_css.cfm?T1ID=13&T2ID=62}}{{dead link|date=June 2012}}</ref>

Chiropractic philosophy includes the following perspectives:<ref name=Chiro-Beliefs>{{cite book|chapterurl=http://chiroweb.com/archives/ahcpr/chapter2.htm|chapter= Chiropractic belief systems|author= Mootz RD, Phillips RB|year=1997|title= Chiropractic in the United States: Training, Practice, and Research|pages=9–16|editor= Cherkin DC, Mootz RD (eds.)|accessdate=2008-02-14|location= Rockville, MD|publisher= [[Agency for Health Care Policy and Research]]|oclc=39856366}} AHCPR Pub No. 98-N002.</ref>

*'''[[Reductionism]]''' in chiropractic reduces causes and cures of health problems to a single factor, [[#Vertebral subluxation|vertebral subluxation]].<ref name=Murphy-pod>{{cite journal|author= Murphy DR, Schneider MJ, Seaman DR, Perle SM, Nelson CF|title= How can chiropractic become a respected mainstream profession? The example of podiatry|journal= Chiropr Osteopat|volume=16|page=10|year=2008|pmid=18759966|doi=10.1186/1746-1340-16-10|url=http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2538524/pdf/1746-1340-16-10.pdf|pmc= 2538524}}</ref> in contrast to '''[[holism]]''' which assumes that health is affected by everything in an individual's environment; some sources also include a spiritual or [[Existentialism|existential]] dimension.<ref>{{cite journal|journal= Br J Gen Pract|year=2005|volume=55|issue=511|pages=154–5|title= Towards a definition of holism|author= Freeman J|pmc=1463203|pmid=15720949}}</ref>
*'''Conservatism''' considers the risks of clinical interventions when balancing them against their benefits. It emphasizes [[noninvasive]] treatment to minimize risk, and avoids [[surgery]] and [[medication]].<ref name=ACA-history/>
*'''[[Homeostasis]]''' emphasizes the body's inherent self-healing abilities. Chiropractic's early notion of [[innate intelligence]] can be thought of as a metaphor for homeostasis.<ref name=Keating05/>
* Straights tend to use an approach that focuses on the chiropractor's perspective and the treatment model, whereas mixers tend to focus on the patient and the patient's situation.<ref name=Chiro-Beliefs/>

=== Straights and mixers ===
{| class="wikitable" style="float:right; margin-left:0.4em;"
|+ Range of belief perspectives in chiropractic
! perspective attribute
! colspan=2| potential belief endpoints
|-
| align=right| scope of practice:
| align=right| narrow ("straight") ←||→ broad ("mixer")
|-
| align=right| diagnostic approach:
| align=right| intuitive ←||→ analytical
|-
| align=right| philosophic orientation:
| align=right| vitalistic ←||→ materialistic
|-
| align=right| scientific orientation:
| align=right| descriptive ←||→ experimental
|-
| align=right| process orientation:
| align=right| implicit ←||→ explicit
|-
| align=right| practice attitude:
| align=right| doctor/model-centered ←||→ patient/situation-centered
|-
| align=right| professional integration:
| align=right| separate and distinct ←||→ integrated into mainstream
|-
| style="text-align:center;" colspan="3"|''Taken from Mootz & Phillips 1997''<ref name=Chiro-Beliefs/>
|}
''Straight'' chiropractors adhere to the philosophical principles set forth by D.D. and B.J. Palmer, and retain [[Metaphysics|metaphysical]] definitions and [[vitalistic]] qualities. Straight chiropractors believe that vertebral subluxation leads to interference with an "[[innate intelligence]]" exerted via the human nervous system and is a primary underlying risk factor for many diseases. Straights view the medical diagnosis of patient complaints (which they consider to be the "secondary effects" of subluxations) to be unnecessary for chiropractic treatment. Thus, straight chiropractors are concerned primarily with the detection and correction of vertebral subluxation via adjustment and do not "mix" other types of therapies into their practice style.<ref name=History-Primer/>

Their philosophy and explanations are metaphysical in nature and they prefer to use traditional chiropractic lexicon terminology (i.e. perform spinal analysis, detect subluxation, correct with adjustment, etc.). They prefer to remain separate and distinct from mainstream health care. Although considered the minority group, "they have been able to transform their status as purists and heirs of the lineage into influence dramatically out of proportion to their numbers."<ref name="Kaptchuk-Eisenberg"/>

''Mixer'' chiropractors "mix" diagnostic and treatment approaches from osteopathic, medical, and chiropractic viewpoints. Unlike straight chiropractors, mixers believe subluxation is one of many causes of disease, and they incorporate mainstream medical diagnostics and employ many treatments including conventional techniques of [[physical therapy]] such as exercise, [[massage]], [[ice pack]]s, and [[moist heat]], along with [[nutritional supplements]], [[acupuncture]], [[homeopathy]], [[Herbalism|herbal remedies]], and [[biofeedback]]. Mixers tend to be open to mainstream medicine and are the majority group.<ref name=Kaptchuk-Eisenberg>{{cite journal|journal=[[Arch Intern Med]]|year=1998|volume=158|issue=20|pages=2215–24|title=Chiropractic: origins, controversies, and contributions|author=Kaptchuk TJ, Eisenberg DM|pmid=9818801|url=http://archinte.ama-assn.org/cgi/content/full/158/20/2215|doi=10.1001/archinte.158.20.2215 }}</ref>

Although mixers are the majority group, many of them retain some belief in vertebral subluxation as shown in a 2003 survey of 1100 North American chiropractors, which found that 88% wanted to retain the term "vertebral subluxation complex", and that when asked to estimate the percent of disorders of internal organs (such as the heart, the lungs, or the stomach) that subluxation significantly contributes to, the mean response was 62%.<ref name=McDonald/> Despite this finding, a 2008 survey of 6000 American chiropractors demonstrated that most chiropractors seem to believe that a subluxation-based clinical approach may be of limited utility for addressing visceral disorders, and greatly favored non-subluxation-based clinical approaches for such conditions.<ref name=Smith&Carber>{{cite journal|journal=[[J Chiropr Human]]|year=2008|volume=15|issue=|pages=19–26|title=Survey of US Chiropractor Attitudes and Behaviors about Subluxation|author=Smith M, Carber LA|pmid=|url=http://archive.journalchirohumanities.com/Vol%2015/JChiroprHumanit2008v15-19-26.pdf|doi= }}</ref><ref>{{cite journal|journal=[[Chiropractic & Manual Therapies]]|year=2011|volume=19|issue=4|pages=|title=The prevalence of the term subluxation in North American English-Language Doctor of chiropractic programs|author=Mirtz TA, Perle SM |pmid=21682859|url=http://chiromt.com/content/19/1/14|doi=10.1186/2045-709X-19-14 }}</ref>

=== Vertebral subluxation ===
{{Main|Vertebral subluxation}}
Palmer hypothesized that vertebral joint misalignments, which he termed ''vertebral subluxations'', interfered with the body's function and its inborn (innate) ability to heal itself.<ref name=History-PPC>{{cite book|author= [[Joseph C. Keating, Jr.|Keating JC Jr]]|chapter= A brief history of the chiropractic profession|pages=23–64|title= Principles and Practice of Chiropractic|edition=3rd|editor= Haldeman S, Dagenais S, Budgell B ''et al.'' (eds.)|publisher=McGraw-Hill|year=2005|isbn=0-07-137534-1}}</ref> D.D. Palmer repudiated his earlier theory that vertebral subluxations caused pinched nerves in the intervertebral spaces in favor of subluxations causing altered nerve vibration, either too tense or too slack, affecting the tone (health) of the end organ. D.D. Palmer, using a vitalistic approach, imbued the term ''subluxation'' with a metaphysical and [[philosophical]] meaning. He qualified this by noting that knowledge of innate intelligence was not essential to the competent practice of chiropractic.<ref>{{cite web|url=http://chiro.org/Plus/History/Persons/PalmerDD/PalmerDD's_Forgotten_Theories1995.pdf|format=PDF|title= D.D. Palmer's forgotten theories of chiropractic|author= Keating JC Jr|publisher= [[Association for the History of Chiropractic]]|year=1995|accessdate=2008-05-14}}</ref> This concept was later expanded upon by his son, B.J. Palmer and was instrumental in providing the legal basis of differentiating chiropractic medicine from conventional medicine. In 1910, D.D. Palmer theorized that the nervous system controlled health:

:"Physiologists divide nerve-fibers, which form the nerves, into two classes, afferent and efferent. Impressions are made on the peripheral afferent fiber-endings; these create sensations that are transmitted to the center of the nervous system. Efferent nerve-fibers carry impulses out from the center to their endings. Most of these go to muscles and are therefore called motor impulses; some are secretory and enter glands; a portion are inhibitory, their function being to restrain secretion. Thus, nerves carry impulses outward and sensations inward. The activity of these nerves, or rather their fibers, may become excited or allayed by impingement, the result being a modification of functionality—too much or not enough action—which is disease."<ref>{{cite book|author= Palmer DD|title= The Chiropractor's Adjuster: Text-book of the Science, Art and Philosophy of Chiropractic for Students and Practitioners|url=http://www.scribd.com/doc/45233534/s-Adjuster-1910|location=Portland, OR|publisher= Portland Printing House Co|year=1910|oclc=17205743}}</ref>

Vertebral subluxation, a core concept of traditional chiropractic, remains unsubstantiated and largely untested, and a debate about whether to keep it in the chiropractic paradigm has been ongoing for decades.<ref name=Keating-subluxation/> In general, critics of traditional subluxation-based chiropractic (including chiropractors) are skeptical of its clinical value, [[dogmatic]] beliefs and metaphysical approach. While straight chiropractic still retains the traditional vitalistic construct espoused by the founders, evidence-based chiropractic suggests that a mechanistic view will allow chiropractic care to become integrated into the wider health care community.<ref name=Keating-subluxation>{{cite journal|journal=[[Chiropr Osteopat]]|year=2005|volume=13|page=17|title=Subluxation: dogma or science?|author=Keating JC Jr, Charlton KH, Grod JP, Perle SM, Sikorski D, Winterstein JF|doi=10.1186/1746-1340-13-17|pmid=16092955|url=http://chiroandosteo.com/content/13/1/17|pmc=1208927|issue=1}}</ref> This is still a continuing source of debate within the chiropractic profession as well, with some schools of chiropractic still teaching the traditional/straight subluxation-based chiropractic, while others have moved towards an [[evidence-based]] chiropractic that rejects metaphysical foundings and limits itself to primarily neuromusculoskeletal conditions.<ref>{{cite journal|journal=[[J Chiropr Educ]]|year=2000|volume=14|issue=2|pages=71–7|title=A survey of the use of evidence-based health care in chiropractic college clinics|author=Rose KA, Adams A|url=http://www.journalchiroed.com/2000/JCEFall2000Rose.PDF|format=PDF }}</ref><ref>{{cite journal|journal=[[J Man Manip Ther]]|year=2006|volume=14|issue=2|pages=E14–8|title=Can chiropractors and evidence-based manual therapists work together? an opinion from a veteran chiropractor|author=Homola S|url=http://jmmtonline.com/documents/HomolaV14N2E.pdf|format=PDF }}</ref>

In 2005, the chiropractic subluxation was defined by the [[World Health Organization]] as "a lesion or dysfunction in a joint or motion segment in which alignment, movement integrity and/or physiological function are altered, although contact between joint surfaces remains intact. It is essentially a functional entity, which may influence biomechanical and neural integrity." This differs from the medical definition of subluxation as a significant structural displacement, which can be seen with static imaging techniques such as [[Radio diagnostics|X-rays]].<ref name=WHO-guidelines>{{cite journal |author= World Health Organization|year=2005|title= WHO guidelines on basic training and safety in chiropractic|url=http://www.who.int/medicines/areas/traditional/Chiro-Guidelines.pdf|format=PDF|isbn= 92-4-159371-7|accessdate=2008-02-29}}</ref>

The 2008 book ''[[Trick or Treatment]]'' states "X-rays can reveal neither the subluxations nor the innate intelligence associated with chiropractic philosophy, because they do not exist."<ref name=Trick-or-Treatment/> Attorney David Chapman-Smith, Secretary-General of the [[World Federation of Chiropractic]], has stated that "Medical critics have asked how there can be a subluxation if it cannot be seen on x-ray. The answer is that the chiropractic subluxation is essentially a functional entity, not structural, and is therefore no more visible on static x-ray than a limp or headache or any other functional problem."<ref>{{cite book|page=160|chapter=Principles and Goals of Chiropractic Care|title=The Chiropractic Profession: Its Education, Practice, Research and Future Directions|author=David Chapman-Smith|year=2000|publisher=NCMIC Group|isbn=1-892734-02-8}}</ref> The [[General Chiropractic Council]], the statutory regulatory body for chiropractors in the United Kingdom, states that the chiropractic vertebral subluxation complex "is not supported by any clinical research evidence that would allow claims to be made that it is the cause of disease."<ref>{{cite web| url=http://www.gcc-uk.org/files/link_file/Guidance_on_claims_made_for_the_chiropractic_VSC_18August10.pdf| format=PDF|title=Guidance on claims made for the chiropractic vertebral subluxation complex| publisher=General Chiropractic Council|accessdate=2010-09-30}}</ref>


== Scope of practice ==
== Scope of practice ==
Chiropractors emphasize the conservative management of the neuromusculoskeletal system without the use of medicines or surgery <ref name=WHO-guidelines/> with an emphasis on the spinal manipulation.<ref name=Nelson>{{cite journal |journal=Chiropr Osteopat |year=2005 |volume=13 |pages=9 |title=Chiropractic as spine care: a model for the profession |author=Nelson CF, Lawrence DJ, Triano JJ ''et al.'' |doi=10.1186/1746-1340-13-9 |pmid=16000175 |url=http://chiroandosteo.com/content/13/1/9 |pmc=1185558 |issue=1}}</ref> Chiropractors are generally regarded as primary contact, portal of entry health care providers. Although chiropractors have many attributes of [[primary care]] providers, chiropractic has more attributes of a limited medical specialty like [[dentistry]] or [[podiatry]].<ref name=Meeker-Haldeman>{{cite journal |journal=[[Ann Intern Med]] |year=2002 |volume=136 |issue=3 |pages=216–27 |title=Chiropractic: a profession at the crossroads of mainstream and alternative medicine |author=Meeker WC, Haldeman S |pmid=11827498 |url=http://www.annals.org/cgi/reprint/136/3/216.pdf |format=PDF }}</ref> Chiropractors are licensed to communicate a neuromusculoskeletal [[diagnosis]] and order X-rays and may use broad diagnostic methods including skeletal imaging, observational and tactile assessments as well as orthopedic and neurological evaluation.<ref name=WHO-guidelines/> A chiropractor may also refer a patient to an appropriate specialist, or co-manage with another health care provider.<ref name=Meeker-Haldeman/> Common patient management involves [[spinal manipulation]] (SM) and other manual therapies to the joints and soft tissues, rehabilitative exercises, health promotion, electrical modalities, complementary procedures, and lifestyle counseling.<ref name=content-of-practice>{{cite book |chapterurl=http://chiroweb.com/archives/ahcpr/chapter3.htm |chapter= Content of practice |author= Mootz RD, Shekelle PG |year=1997 |title= Chiropractic in the United States: Training, Practice, and Research |pages=67–91 |editor= Cherkin DC, Mootz RD (eds.) |accessdate=2008-10-10 |location= Rockville, MD |publisher= Agency for Health Care Policy and Research |oclc=39856366}} AHCPR Pub No. 98-N002.</ref> When indicated chiropractors may also refer a patient to an appropriate specialist, or co-manage with another health care provider.<ref name=Meeker-Haldeman/>
[[File:Therapeutic chairs.jpg|thumb|right|alt=|Therapeutic chairs at a chiropractic office in New Jersey.]]


Due to the historical differences in philosophy and treatment approaches, there are range of 'broad' and 'narrow' scopes of practice for American chiropractors which tend to reflect 'straight' or 'mixer' underpinnings. <ref name=Parkman>{{cite journal |author=Parkman CA |title=Issues in credentialing CAM providers |journal=Case Manager |volume=15 |issue=4 |pages=24–7 |year=2004 |pmid=15247891 |doi=10.1016/j.casemgr.2004.05.004 }}</ref> A focus on evidence-based research has also raised concerns that the resulting practice guidelines could limit the scope of chiropractic practice to treating backs and necks.<ref name=Villanueva-Russell>{{cite journal |journal= [[Soc Sci Med]] |year=2005 |volume=60 |issue=3 |pages=545–61 |title= Evidence-based medicine and its implications for the profession of chiropractic |author= Villanueva-Russell Y |doi=10.1016/j.socscimed.2004.05.017 |pmid=15550303}}</ref> however the majority of chiropractors currently view themselves as "back/neck pain musculoskeletal specialists<ref name="V-H">{{cite doi|10.1016/j.socscimed.2011.03.038}}</ref> The vast majority who seek chiropractic care do so for relief from back and neck pain and other neuromusculoskeletal complaints;<ref>{{cite journal|journal= [[BMC Health Serv Res]]|year=2006|volume=6|issue=49|title= A comparative analysis of chiropractic and general practitioner patients in North America: Findings from the joint Canada/United States survey of health, 2002–03|author= Hurwitz EL, Chiang LM|doi=10.1186/1472-6963-6-49|pmid=16600038|url=http://www.biomedcentral.com/1472-6963/6/49|page=49|pmc= 1458338}}</ref>most do so specifically for low back pain.<ref name=Lawrence-Meeker/> Although it is generally accepted that chiropractic care is appropriate for musculoskeletal complaints, there is considerable debate on their role in treating visceral disorders..<ref>{{cite journal |author=Gleberzon BJ, Cooperstein R, Perle SM |title=Can chiropractic survive its chimerical nature? |journal=J Can Chiropr Assoc |volume=49 |issue=2 |pages=69–73 |year=2005 |pmid=17549192 |pmc=1840015 }}</ref> Certain jurisdictions allows the practice [[veterinary chiropractic|animal chiropractic]], whereby licensed chiropractors and [[veterinarians]] practice manual and manipulative therapies on animals for musculoskeletal disorders.<ref>{{cite journal |author=Ramey DW |title=Regulatory aspects of complementary and alternative veterinary medicine |journal=J Am Vet Med Assoc |volume=222 |issue=12 |pages=1679–82 |year=2003 |pmid=12830858 |doi= 10.2460/javma.2003.222.1679 }}</ref> Increasing evidence-based practice and aligning with conventional medicine has been suggested to obtain more university affiliation and access to hospitals and long-term facilities; aligning with the CAM movement could bring more patients looking for nonmedical approaches.<ref>{{cite book |author=[[#TSC|Cooperstein & Gleberzon]] |chapter=Current and future utilization rates and trends |pages=297–305 }}</ref>
In 2005 the [[World Health Organization|WHO]] published a document, ''WHO guidelines on basic training and safety in chiropractic'' that characterized chiropractic as a practice which "emphasizes the conservative management of the neuromusculoskeletal system, without the use of medicines and surgery".<ref name=WHO-guidelines/> Nelson ''et al'' wrote, also in 2005, that one characteristic of chiropractic is a particular emphasis on the spine.<ref name=Nelson>{{cite journal|journal=Chiropr Osteopat|year=2005|volume=13|page=9|title=Chiropractic as spine care: a model for the profession|author=Nelson CF, Lawrence DJ, Triano JJ ''et al.''|doi=10.1186/1746-1340-13-9|pmid=16000175|pmc=1185558|issue=1}}</ref> In 2011 research by Yvonne Villanueva-Russell found a range of opinions among chiropractors: some believed that treatment should be confined to the spine, or back and neck pain; other vehemently disagreed. For example, while one 2009 survey of American chiropractors had found that 73% classified themselves as "back pain/musculoskeletal specialists", the label "back and neck pain specialists" was regarded by 47% of them as a ''least'' desirable description in a 2005 international survey.<ref name="V-H">{{cite doi|10.1016/j.socscimed.2011.03.038}}</ref>
In 2005, the World Health Organization developed chiropractic guidelines on basic training and safety to help standardize formal accreditation and licensure of chiropractors in countries where they remain unregulated. ,<ref name=WHO-guidelines/>. Currently, chiropractic medicine is regulated and practiced in over 100 countries, however chiropractors are most prevalent in [[North America]], [[Australia]] and parts of [[Europe]]. The majority of mainstream health care and governmental organizations classify chiropractic as traditional or complementary alternative medicine<ref name=Chapman-Smith/>


==History==
Chiropractic overlaps with several other forms of manual therapy, including [[massage therapy]], [[osteopathy]], [[physical therapy]], and [[sports medicine]].<ref name=Norris/><ref>{{cite journal|journal=Sociol Health Illn.|year=2008|volume=30|pages=19–34|title=The integration of chiropractors into healthcare teams: a case study from sport medicine|author=Theberge N|doi=10.1111/j.1467-9566.2007.01026.x|pmid=18254831|issue=1}}</ref> Chiropractic is autonomous from and competitive with mainstream medicine,<ref name=Pettman/> and osteopathy outside the US remains primarily a manual medical system;<ref>{{cite journal|journal= Complement Health Pract Rev|year=2006|volume=11|issue=2|pages=77–94|doi=10.1177/1533210106292467|title= The drive for legitimization by osteopathy and chiropractic in Australia: between heterodoxy and orthodoxy|author= Baer HA}}</ref> physical therapists work alongside and cooperate with mainstream medicine, and [[osteopathic medicine in the U.S.]] has merged with the medical profession.<ref name=Pettman>{{cite journal|doi=10.1179/106698107790819873|author=Pettman E|title=A History of Manipulative Therapy|journal=J Man Manip Ther|volume=15|issue=3|pages=165–74|year=2007|pmid=19066664|pmc=2565620}}</ref> Practitioners may distinguish these competing approaches through claims that, compared to other therapists, chiropractors heavily emphasize spinal manipulation, tend to use firmer manipulative techniques, and promote maintenance care; that osteopaths use a wider variety of treatment procedures; and that physical therapists emphasize machinery and exercise.<ref name=Norris>{{cite journal|author= Norris P|year=2001|title= How 'we' are different from 'them': occupational boundary maintenance in the treatment of musculo-skeletal problems|journal= Sociol Health Illn|volume=23|issue=1|pages=24–43|doi=10.1111/1467-9566.00239}}</ref>
Upon its founding 1895, chiropractic's early philosophy was rooted in [[vitalism]], [[naturalism]], [[magnetism]], [[spiritualism]] and other constructs that were not amenable to the [[scientific method]]. Chiropractic's founder, D.D. Palmer, attempted to merge [[science]] and [[metaphysics]].<ref name="Leach 2004 15">{{cite book|last=Leach|first=Robert|title=The Chiropractic Theories: A Textbook of Scientific Research|year=2004|publisher=Lippincott, Williams and Wilkins|isbn=0683307479|pages=15}}</ref> In 1896, D.D. Palmer's first descriptions and underlying philosophy of chiropractic was strikingly similar to Andrew Still's [[Osteopathic medicine in the United States#Osteopathic Principles|principles of osteopathy]] established a decade earlier.<ref name=Ernst-eval/> Both described the body as a "machine" whose parts could be manipulated to produce a drugless cure. Both professed the use of spinal manipulation on joint dysfunction/subluxation to improve health. Palmer drew further distinctions by noting that he was the first to use short-lever HVLA manipulative techniques using the [[spinous process]] and [[transverse processes]] as mechanical levers. Additionally he described the effects of chiropractic spinal manipulation was mediated by the nervous system in contrast to osteopathy who believed the effects were attributed to the supremacy of the [[circulatory system]]. <ref name="lifeline">{{cite web|url=http://www.chiro.org/Plus/History/Persons/PalmerDD/PalmerDD's-Lifeline-chrono.pdf |title=98_04_13~1.PDF |format=PDF |date= |accessdate=2010-10-14}}</ref> Palmer initially denied being trained by [[osteopathic medicine]] founder [[A.T. Still]]. But Palmer's papers, held at the [[Palmer College of Chiropractic]], indicate that he wrote in 1899:


: ''"Some years ago I took and expensive course in Electropathy, Cranial Diagnosis, Hydrotherapy, Facial Diagnosis. Later I took Osteopathy [which] gave me such a measure of confidence as to almost feel it unnecessary to seek other sciences for the mastery of curable disease. Having been assured that the underlying philosophy of chiropractic is the same as that of osteopathy...Chiropractic is osteopathy gone to seed."''<ref name="Leach 2004 15"/>
[[File:Xray Machine Champion Chiropractic.jpg|thumb|right|alt=|Chiropractors controversially make extensive use of x-ray radiography.]]
Chiropractic diagnosis may involve a range of methods methods including skeletal imaging, observational and tactile assessments, and orthopedic and neurological evaluation.<ref name=WHO-guidelines/> A chiropractor may also refer a patient to an appropriate specialist, or co-manage with another health care provider.<ref name=Meeker-Haldeman/> Common patient management involves [[spinal manipulation]] (SM) and other manual therapies to the joints and soft tissues, rehabilitative exercises, health promotion, electrical modalities, complementary procedures, and lifestyle advice.<ref name=content-of-practice>{{cite book|chapterurl=http://chiroweb.com/archives/ahcpr/chapter3.htm|chapter= Content of practice|author= Mootz RD, Shekelle PG|year=1997|title= Chiropractic in the United States: Training, Practice, and Research|pages=67–91|editor= Cherkin DC, Mootz RD (eds.)|accessdate=2008-10-10|location= Rockville, MD|publisher= Agency for Health Care Policy and Research|oclc=39856366}} AHCPR Pub No. 98-N002.</ref>


Despite their similarities, osteopathic practitioners sought to differentiate themselves by seeking [[licensure]] to [[regulate]] the profession calling chiropractic a "bastardized form of osteopathy"<ref name=Ernst-eval/> In 1907 in a test of the new osteopathy law, a [[Wisconsin]] based chiropractor was charged with [[practicing without a license|practicing osteopathic medicine without a license]]. Ironically the Palmers legal defence of chiropractic consisted of the first chiropractic textbook 'Modernized Chiropractic' published in 1906, written by "mixer" chiropractors Longworthy, Smith et al. who the Palmers despised. Although the chiropractors won their first test case in Wisconsin in 1907, prosecutions instigated by state medical boards became increasingly common and in many cases were successful. In response, chiropractors conducted political campaigns to secure separate licensing statutes, eventually succeeding in all fifty states, from Kansas in 1913 through Louisiana in 1974.<ref name="History-Primer">{{cite web|title= Chiropractic history: a primer|author= [[Joseph C. Keating, Jr.]], Cleveland CS III, Menke M|url=http://data.memberclicks.com/site/ahc/ChiroHistoryPrimer.pdf|format=PDF|year=2005|accessdate=2008-06-16|publisher= Association for the History of Chiropractic|quote=A significant and continuing barrier to scientific progress within chiropractic are the anti-scientific and pseudo-scientific ideas (Keating 1997b) which have sustained the profession throughout a century of intense struggle with political medicine. Chiropractors' tendency to assert the meaningfulness of various theories and methods as a counterpoint to allopathic charges of quackery has created a defensiveness which can make critical examination of chiropractic concepts difficult (Keating and Mootz 1989). One example of this conundrum is the continuing controversy about the presumptive target of DCs' adjustive interventions: subluxation (Gatterman 1995; Leach 1994).}}</ref> In this regard, chiropractic is unique with CAM disciplines in North America having achieved regulation in all American states and Canadian provinces.<ref name="V-H">{{cite doi|10.1016/j.socscimed.2011.03.038}}</ref> By embracing both vitalism and materialism the philosophy of chiropractic has produced a diverse and eclectic mix of chiropractors which despite their emphasis of manual therapy they may vary on their perceived scope of practice, interventions and their role in the health care system.<ref name="Keating05">{{cite book |author= Keating JC Jr |chapter= Philosophy in chiropractic |pages=77–98 |title= Principles and Practice of Chiropractic |edition= 3rd ed. |editor= Haldeman S, Dagenais S, Budgell B ''et al.'' (eds.) |publisher=McGraw-Hill |year=2005 |isbn=0-07-137534-1}}</ref>
Chiropractors are not normally licensed to write [[medical prescription]]s or perform major surgery in the U.S.,<ref name=Parkman/> (although [[New Mexico]] has become the first US state to allow "advanced practice" trained chiropractors to prescribe certain medications.<ref>[http://www.nmcpr.state.nm.us/nmac/parts/title16/16.004.0015.htm Occupational And Professional Licensing, Chiropractic Practitioners, Chiropractic Advanced Practice Certification Registry]. Retrieved 2010-05-03.</ref><ref>[http://www.rld.state.nm.us/Chiropractic/PDFs/RuleChanges/NMAC%2016.4.15.pdf Occupational And Professional Licensing, Chiropractic Practitioners, Chiropractic Advanced Practice Certification Registry (PDF)]{{dead link|date=June 2012}}. Retrieved 2010-05-03.</ref>). In the US, their scope of practice varies by state, based on inconsistent views of chiropractic care: some states, such as Iowa, broadly allow treatment of "human ailments"; some, such as Delaware, use vague concepts such as "transition of nerve energy" to define scope of practice; others, such as New Jersey, specify a severely narrowed scope.<ref name=Morrison>{{cite journal|author=Morrison P|title=Adjusting the role of chiropractors in the United States: why narrowing chiropractor scope of practice statutes will protect patients|journal=Health Matrix Clevel|volume=19|issue=2|pages=493–537|year=2009|pmid=19715143 }}</ref>


===Philosophy===
US States also differ over whether chiropractors may conduct laboratory tests or diagnostic procedures, dispense [[dietary supplement]]s, or use other therapies such as homeopathy and acupuncture; in [[Oregon]] they can become certified to perform minor surgery and to deliver children via natural childbirth.<ref name=Parkman>{{cite journal|author=Parkman CA|title=Issues in credentialing CAM providers|journal=Case Manager|volume=15|issue=4|pages=24–7|year=2004|pmid=15247891|doi=10.1016/j.casemgr.2004.05.004 }}</ref> A 2003 survey of North American chiropractors found that a slight majority favored allowing them to write prescriptions for [[over-the-counter drug]]s.<ref name=McDonald>{{cite book|author=McDonald WP, Durkin KF, Pfefer M ''et al.''|year=2003|title=How Chiropractors Think and Practice: The Survey of North American Chiropractors|location=Ada, OH|publisher=Institute for Social Research, Ohio Northern University|isbn=0-9728055-5-9 }} Summarized in: {{cite journal|journal=Semin Integr Med|year=2004|volume=2|issue=3|pages=92–8|title=How chiropractors think and practice: the survey of North American chiropractors|author=McDonald WP, Durkin KF, Pfefer M|doi=10.1016/j.sigm.2004.07.002|laydate=2003-06-02|laysummary=http://chiroweb.com/archives/21/12/19.html|laysource= Dyn Chiropr }}</ref>
The philosophy of chiropractic shares both vitalistic and mechanistic viewpoints and embrace naturalistic principles that suggest decreased "host resistance" of the body facilitates the disease process and that natural interventions are preferable towards strengthening the host in its effort to optimize function and return to [[homeostasis]].<ref name="Chiro-Beliefs" /> The chiropractor's purpose is to foster the establishment and maintenance of an organism-environment dynamic that is the most conducive to functional well-being of the person as a whole.<ref name="Chiro-Beliefs" /> Chiropractic care primarily emphasizes manipulation and other manual therapies as an alternative to [[medications]] and [[surgery]].<ref>{{cite book |editor= Mootz RD, Hansen DT |title= Chiropractic technologies |publisher= Jones & Bartlett |year=1999 |isbn=0834213737 |author= Hansen DT, Mootz RD |chapter= Formal processes in health care technology assessment: a primer for the chiropractic profession |pages=3–17}}</ref> The relationship between structure, especially the spine, and function as modulated by the nervous system, is central to chiropractic and its approach to the restoration and preservation of health. Chiropractors examine the [[biomechanics]] of the spine and other structures of the [[musculoskeletal|neuromusculoskeletal]] and its role in health and disease.<ref name="ACA-history">{{cite web|title= History of chiropractic care|author= [[American Chiropractic Association]]|accessdate=2008-02-21|url=http://acatoday.org/level2_css.cfm?T1ID=13&T2ID=62}}{{dead link|date=June 2012}}</ref> It is hypothesized that significant neurophysiological consequences may occur as a result of mechanical spinal functional disturbances, described by chiropractors as the vertebral subluxation complex<ref name="Coulter 1999 19–29">{{cite book|last=Coulter|first=ID|title=Chiropractic: A Philosophy for Alternative Health Care|year=1999|publisher=Butterworth-Heinemann|isbn=0750640065|pages=19–29}}</ref>
Most practitioners currently accept the importance of scientific research into chiropractic.<ref name="Keating05">{{cite book|author= Keating JC Jr|chapter= Philosophy in chiropractic|pages=77–98|title= Principles and Practice of Chiropractic|edition=3rd|editor= Haldeman S, Dagenais S, Budgell B ''et al.'' (eds.)|publisher=[[McGraw-Hill]]|year=2005|isbn=0-07-137534-1}}</ref> Foundational concepts of the philosophy of chiropractic include:
{{quotation|
* Vitalism accepts that all living organisms are sustained by a vital force that is both different from, and greater than, physical and chemical forces. Contemporary is it is referred to as "vis medicatrix naturae" (the healing power of nature).
*Holism postulates that health is related to the balanced integration of the individual in all aspects and levels of being: body, mind and spirit, including interpersonal relationships and the interplay between lifestyle, environment, and health.
*Naturalism states a preference for natural remedies. This is bound up with a set of philosophical principles which may be expressed as the body is built on nature’s order, it has natural ability to heal itself, that this is reinforced by the use of natural remedies, that it should not be tampered with unnecessarily through the use of drugs or surgery
*Humanism is based on the postulate that individuals have immutable rights, for example the right to dignity. In CAM there is extensive concern about dehumanizing procedures and the dehumanizing institutions that have been created for the ill. Partly it is recognition of the personal, social and spiritual aspects of health and a move away from simply the biology of health.
*Therapeutic Conservatism is the use therapies that have a low level of side effects and it tends to accept that the least care is the best care. This in some ways is derived from earlier principles. if the body is capable of healing itself, the role of the therapy is simply to initiate the process.<ref name="Coulter 1999 19–29"/>}}


==="Straight" chiropractic===
A related field, [[veterinary chiropractic]], applies manual therapies to animals and is recognized in a few U.S. states,<ref>{{cite journal|author=Ramey DW|title=Regulatory aspects of complementary and alternative veterinary medicine|journal=J Am Vet Med Assoc|volume=222|issue=12|pages=1679–82|year=2003|pmid=12830858|doi= 10.2460/javma.2003.222.1679 }}</ref> but is not recognized by the [[American Chiropractic Association]] as being chiropractic.<ref>{{cite web|url=http://amerchiro.org/level2_css.cfm?T1ID=10&T2ID=117#107|accessdate=2008-07-05|title='Veterinary' chiropractic|year=1994|author=ACA House of Delegates|publisher=American Chiropractic Association }}</ref>
[[Image:Daniel David Palmer.jpg|thumb|upright|alt=Half-length sitting portrait of man in his fifties with large gray beard and moustache, wearing coat and vest|]]
Also known as 'subluxation-based' and 'principled chiropractic', chiropractors educated from this paradigm espouse traditional Palmer principles and philosophy. Historically straight chiropractors regarded spinal joint dsyfunction/subluxation as the primary cause of "dis-ease" and could be corrected via specific chiropractic adjustments. This monocausal view of disease has been abandoned by the profession <ref>{{cite book|last=Bergmann, T.F.|first=Perterson D.H|title=Chiropractic Technique: Principles and Procedures|year=2011|publisher=Elsevier|isbn=9780323049696}}</ref> preferring a holistic view of subluxation that is viewed as theoretical construct in a"web of causation" along with other determinants of health.<ref name="Henderson 2012 632–642"/> Palmerian philosophy focused on metaphysical constructs such as [[Innate Intelligence]] and [[Universal Intelligence]] to explain the effects of the chiropractic adjustment, whose intent was the reduce/correct spinal subluxations and improving the functioning of the nervous system. The subluxation was said to be "the cause of 95 percent of all diseases... the other five percent is caused by displaced joints other than those of the vertebral column."<ref name="textbook">Palmer D.D., The Science, Art and Philosophy of Chiropractic. Portland, Oregon: Portland Printing House Company, 1910.</ref> Misalignment of the vertebrae was believed to be cause impingement of the nerve root, a theory which has long been debunked<ref>{{cite journal|coauthors=Christopher J. Good|title=The great subluxation debate: a centrist's perspective|journal=Journal of Chiropractic Humanities|year=2010|volume=17|issue=1|pages=33–39|pmid=22693474}}</ref> Subluxation-based chiropractors view traditional chiropractic lexicon such as "analysis" and "adjustment" and as a critical distinction of chiropractic despite lack of prevalence of these terms in the chiropractic literature<ref>{{cite journal|coauthors=Millar N, Budgell BS, Kwong A.|title=Quantitative corpus-based analysis of the chiropractic literature - a pilot study.|journal=Journal of the Canadian Chiropractic Association|year=2011|month=March|volume=55|issue=1|pages=56–60|pmid=21403783|accessdate=7 February 2013}}</ref> Subluxation-based chiropractors have been criticized both internally and externally for far-reaching claims of "killer" subluxations, pseudoscientific reasoning,<ref name="Ernst-eval">{{cite journal|journal= [[J Pain Symptom Manage]]|year=2008|volume=35|issue=5|pages=544–62|title= Chiropractic: a critical evaluation|author= Ernst E|doi=10.1016/j.jpainsymman.2007.07.004|pmid=18280103 }}</ref> dogmatic approaches <ref name="Keating-subluxation">{{cite journal|journal=[[Chiropr Osteopat]]|year=2005|volume=13|page=17|title=Subluxation: dogma or science?|author=Keating JC Jr, Charlton KH, Grod JP, Perle SM, Sikorski D, Winterstein JF|doi=10.1186/1746-1340-13-17|pmid=16092955|url=http://chiroandosteo.com/content/13/1/17|pmc=1208927|issue=1}}</ref>
unethical business practices that invoke religious themes and high-volume treatments for a variety of conditions that lack supportive scientific evidence.<ref>{{cite journal|coauthors=Gleberzon BJ, Cooperstein R, Perle SM.|title=Can chiropractic survive its chimerical nature?|journal=J Can Chiropr Assoc.|year=2005|month=June|volume=49|issue=2|pages=69–73|pmid=17549192|accessdate=7 February 2013}}</ref> This metaphysical and dogmatic and singular approach to chiropractic care has been criticized for failing to engage in critical and rational thinking and embracing [[evidence-based medicine]].<ref name=Murphy-pod/> Straight chiropractors use a subluxation-based model as opposed to the patient-centered model now favored in health care.<ref name="Chiro-Beliefs">{{cite book|chapterurl=http://chiroweb.com/archives/ahcpr/chapter2.htm|chapter= Chiropractic belief systems|author= Mootz RD, Phillips RB|year=1997|title= Chiropractic in the United States: Training, Practice, and Research|pages=9–16|editor= Cherkin DC, Mootz RD (eds.)|accessdate=2008-02-14|location= Rockville, MD|publisher= [[Agency for Health Care Policy and Research]]|oclc=39856366}} AHCPR Pub No. 98-N002.</ref> Although they are the minority within the profession, they are considered to have a disproportionate influence as "purists".<ref name="Kaptchuk-Eisenberg"/>


==="Mixer" chiropractic===
[[File:Treatment Table Chiropractic.jpg|thumb|200px|right|alt=|A treatment table at a chiropractic office.]]
Mixers form the majority of chiropractors and attempt to combine the materialistic reductionism of science with the metaphysics of their predecessors and with the [[Holistic medicine|holistic paradigm of wellness]];<ref name=Chiro-Beliefs/> While D.D. Palmer considered vertebral misalignment to be the hallmark feature of subluxation, mixer pioneer Solon Langworthy asserted that intervertebral hypomobility, not misalignment, was subluxation’s cardinal biomechanical feature. This contrasting mechanistic emphasis, intervertebral misalignment vs. hypomobility, formed one the basis for a heated polemic in the profession. Although both misalignment and hypomobility are currently recognized as biomechanical features of subluxation, hypomobility has garnered much more attention in recent years.<ref name="Henderson 2012 632–642"/><ref>{{cite journal|last=Vernon|first=Howard|title=Historical overview and update on subluxation theories|journal=Journal of Chiropractic Humanities|year=2010|volume=22|issue=1|pages=22–32|doi=10.1016/j.echu.2010.07.001|pmid=22693473|accessdate=28 January 2013}}</ref>
Mixers were disdained by the Palmers who disapproved of their use of instrumentation and mixing chiropractic diagnostic and treatment approaches with osteopathic, naturopathic and allopathic viewpoints.<ref name="Kaptchuk-Eisenberg">{{cite journal|journal=[[Arch Intern Med]]|year=1998|volume=158|issue=20|pages=2215–24|title=Chiropractic: origins, controversies, and contributions|author=Kaptchuk TJ, Eisenberg DM|pmid=9818801|url=http://archinte.ama-assn.org/cgi/content/full/158/20/2215|doi=10.1001/archinte.158.20.2215 }}</ref> By embracing a mechanistic viewpoint, mixers are able balance the vitalistic notions with critical reasoning skills that led to legitimate scientific investigation of chiropractic principles. Mechanistic underpinnings have led to testable hypotheses that structure affects function via the nervous system by the scientific study of joint dysfunction (subluxation) and the biological mechanisms underlying manipulative therapies<ref name="Keating05">{{cite book|author= Keating JC Jr|chapter= Philosophy in chiropractic|pages=77–98|title= Principles and Practice of Chiropractic|edition=3rd|editor= Haldeman S, Dagenais S, Budgell B ''et al.'' (eds.)|publisher=[[McGraw-Hill]]|year=2005|isbn=0-07-137534-1}}</ref> Scientific chiropractors suggests that a mechanistic view will allow chiropractic care to become integrated into the wider health care community.<ref name="Keating-subluxation">{{cite journal|journal=[[Chiropr Osteopat]]|year=2005|volume=13|page=17|title=Subluxation: dogma or science?|author=Keating JC Jr, Charlton KH, Grod JP, Perle SM, Sikorski D, Winterstein JF|doi=10.1186/1746-1340-13-17|pmid=16092955|url=http://chiroandosteo.com/content/13/1/17|pmc=1208927|issue=1}}</ref> In contrast to subluxation-based chiropractors, evidence-based chiropractors favor and incorporate mainstream medical diagnostic and treatment approaches such as [[exercise]], [[nutrition|nutritional supplementation]], [[rehabilitation]], [[self-care]], physiotherapeutic modalities, and other natural approaches. A majority of mixers retain belief that spinal dysfunction/subluxation may be involved in somato-visceral disorders. This group may represent the 'silent majority' of centrists who embrace evidence-based medicine but feel comfortable retaining elements of the subluxation complex that have not been validated through empirical evidence.<ref>{{cite journal|coauthors=Good, CJ|title=The great subluxation debate: a centrist's perspective.|journal=Journal of Chiropractic Humanities|year=2010|volume=17|issue=1|pages=33–39|accessdate=7 February 2013}}</ref>


==Investigations==
== Treatment techniques ==
=== Spinal dysfunction/subluxation ===
{{Main|Chiropractic treatment techniques|Spinal adjustment}}
{{Main|Vertebral subluxation}}
[[Spinal manipulation]], which chiropractors call "spinal adjustment" or "chiropractic adjustment", is the most common treatment used in chiropractic care.<ref name=NBCE_techniques/> Spinal manipulation is a passive manual maneuver during which a three-joint complex is taken past the normal range of movement, but not so far as to dislocate or damage the joint. Its defining factor is a dynamic thrust, which is a sudden force that causes an audible release and attempts to increase a joint's range of motion.<ref name=ACA-SMP/>
Spinal dysfunction dubbed ''subluxation'' by chiropractors, is hypothesized to interfere with optimal biomechanics (structure) thereby altering proper neurological function. Chiropractic theory suggests spinal dysfunction/subluxation may contribute to neuromusculoskeletal and [[visceral]] disorders via aberrant spinal segmental and suprasegmental reflexes.<ref>{{cite journal|coauthors=Bolton PS, Budgell B.|title=Visceral responses to spinal manipulation.|journal=J Electromyogr Kinesiol.|year=2012|month=Oct|volume=22|issue=5|pages=777-784|pmid=22440554|accessdate=9 February 2013}}</ref>Chiropractors suggest spinal manipulation normalizes spine biomechanics, and as a consequence, normalizes afferent input to the central nervous system resulting in optimized neurological function and improved health outcomes.<ref>{{cite journal|coauthors=H. Haavik-Taylor, B. Murphy|title=The effects of spinal manipulation on central integration of dual somatosensory input observed after motor training: a crossover study|journal=JMPT|year=2010|volume=33|issue=4|pages=261–272|accessdate=27 January 2013}}</ref>


Chiropractic emphasis on mechanical joint dysfunction/subluxation and it's putative role in non-musculoskeletal disease has been a source of controversy since its inception in 1895 due its vitalistic and metaphysical origins which used terminology that was not amenable to scientific investigation. Far reaching claims and lack of scientific evidence supporting spinal joint dysfunction as the sole cause of disease has led to a critical evaluation of a central tenet of chiropractic and the appropriateness of the profession's role in treating a broad spectrum disorders that are not related to the neuromusculoskeletal system.<ref name="How can chiropractic become a respected mainstream profession? The example of podiatry.">Murphy DR, Schneider MJ, Seaman DR, Perle SM, Nelson CF.http://www.ncbi.nlm.nih.gov/pubmed/18759966</ref> Today the monocausal view of disease has been abandoned by the profession <ref>{{cite book|last=Bergmann, T.F.|first=Perterson D.H|title=Chiropractic Technique: Principles and Procedures|year=2011|publisher=Elsevier|isbn=9780323049696}}</ref>preferring a holistic view of subluxation that is viewed as theoretical construct in a "web of causation" along with other determinants of health.<ref name="Henderson 2012 632–642"/> Although there is external and internal debate within the chiropractic profession regarding the clinical significance of joint dysfunction/subluxation<ref name="The prevalence of the term subluxation in North American English-Language Doctor of chiropractic programs.">Mirtz TA, Perle SM.http://www.ncbi.nlm.nih.gov/pubmed/21682859</ref> the manipulable lesion remains inextricably linked to the profession as basis for spinal manipulation.<ref name="Henderson 2012 632–642">{{cite journal|last=Henderson|first=C.N.R|journal=Journal of Electromyography and Kinesiology|year=2012|month=October|volume=22|issue=5|pages=632–642|accessdate=27 January 2013}}</ref>
High-velocity, low-amplitude spinal manipulation (HVLA-SM) thrusts have physiological effects that signal neural discharge from paraspinal muscle tissues, depending on duration and amplitude of the thrust are factors of the degree in paraspinal muscle spindles activation. Clinical skill in employing HVLA-SM thrusts depends on the ability of the practitioner to handle the duration and magnitude of the load.<ref>{{cite journal|journal=Spine|year=2007|volume=7|issue=5|pages=583– 95|title= Response of lumbar paraspinal muscles spindles is greater to spinal manipulative loading compared with slower loading under length control|author= Pickar JG, Sung PS, Kang YM, Ge W|pmid=17905321|pmc=2075482|doi=10.1016/j.spinee.2006.10.006|url=http://www.thespinejournalonline.com/article/S1529-9430(06)00973-9/abstract }}</ref> More generally, [[spinal manipulative therapy]] (SMT) describes techniques where the hands are used to manipulate, massage, mobilize, adjust, stimulate, apply traction to, or otherwise influence the spine and related tissues.<ref name=ACA-SMP>{{cite web|url=http://acatoday.org/pdf/spinal_manipulation_policy.pdf|format=PDF|title= Spinal manipulation policy statement|author= Winkler K, Hegetschweiler-Goertz C, Jackson PS ''et al.''|accessdate=2008-05-24|year=2003|publisher= American Chiropractic Association}}</ref>


=== Definitions===
There are several schools of chiropractic adjustive techniques, although most chiropractors mix techniques from several schools. The following adjustive procedures were received by more than 10% of patients of licensed U.S. chiropractors in a 2003 survey:<ref name=NBCE_techniques/> [[Diversified technique]] (full-spine manipulation, employing various techniques), extremity adjusting, [[Activator technique]] (which uses a spring-loaded tool to deliver precise adjustments to the spine), Thompson Technique (which relies on a drop table and detailed procedural protocols), [[Clarence Gonstead#Gonstead Technique|Gonstead]] (which emphasizes evaluating the spine along with specific adjustment that avoids rotational vectors), Cox/flexion-distraction (a gentle, low-force adjusting procedure which mixes chiropractic with osteopathic principles and utilizes specialized adjusting tables with movable parts), adjustive instrument, Sacro-Occipital Technique (which models the spine as a torsion bar), [[Neuromuscular therapy|Nimmo Receptor-Tonus Technique]], [[Applied Kinesiology]] (which emphasises "muscle testing" as a diagnostic tool), and cranial.<ref>{{cite book|title=Technique Systems in Chiropractic|author=Cooperstein R, Gleberzon BJ|publisher=Churchill Livingstone|year=2004|isbn=0-443-07413-5|ref=TSC }}</ref> Medicine-assisted manipulation, such as [[manipulation under anesthesia]], involves sedation or local anesthetic and is done by a team that includes an [[anesthesiologist]]; a 2008 [[systematic review]] did not find enough evidence to make recommendations about its use for chronic low back pain.<ref>{{cite journal|author=Dagenais S, Mayer J, Wooley JR, Haldeman S|title=Evidence-informed management of chronic low back pain with medicine-assisted manipulation|journal=Spine J|volume=8|issue=1|pages=142–9|year=2008|pmid=18164462|doi=10.1016/j.spinee.2007.09.010 }}</ref>
According to the [[ICD-10]] the chiropractic subluxation is a biomechanical lesion or dysfunction in a joint or motion segment in which alignment, movement integrity and/or physiological function are altered, although contact between joint surfaces remains intact. It is essentially a functional entity, which may influence biomechanical and neural integrity.<ref name="WHO ICD-10">{{cite web|title=ICD 10:2010|url=http://apps.who.int/classifications/icd10/browse/2010/en#/M95-M99|publisher=World Health Organization|accessdate=10 February 2013}}</ref> It is also referred to as joint dysfunction, fixation, hypomobility, segmental and somatic dysfunction.


===Theory===
Many other procedures are used by chiropractors for treating the spine, other joints and tissues, and general health issues. The following procedures were received by more than one-third of patients of licensed U.S. chiropractors in a 2003 survey: [[Diversified technique]] (full-spine manipulation; mentioned in previous paragraph), [[physical fitness]]/[[exercise]] promotion, corrective or therapeutic exercise, [[ergonomic]]/[[Neutral spine|postural]] advice, [[self-care]] strategies, [[activities of daily living]], changing risky/unhealthy behaviors, [[Diet (nutrition)|nutritional/dietary]] recommendations, [[Relaxation technique|relaxation]]/[[stress reduction]] recommendations, [[Cryotherapy|ice pack/cryotherapy]], extremity adjusting (also mentioned in previous paragraph), [[Neuromuscular therapy|trigger point therapy]], and [[disease prevention]]/early [[Screening (medicine)|screening]] advice.<ref name=NBCE_techniques>{{cite book|title= Job Analysis of Chiropractic|chapter= Professional functions and treatment procedures|year=2005|pages=121–38|author= Christensen MG, Kollasch MW|location= Greeley, CO|publisher= [[National Board of Chiropractic Examiners]]|chapterurl=http://nbce.org/pdfs/job-analysis/chapter_10.pdf|format=PDF|accessdate=2008-08-25|isbn=1-884457-05-3}}{{dead link|date=June 2012}}</ref>
Although many theories have been put forth to explain the putative effects of subluxation that are reported in clinical practice, they may be broadly classified into three mechanism-oriented categories that are not mutually exclusive <ref name="Cramer 2005 296–303">{{cite book|last=Cramer|first=CN|title=Three neurophysiologic theories on the chiropractic subluxation|year=2005|publisher=Mosby|location=St-Louis|pages=296–303}}</ref>


1. ''Encroachment of the intervertebral foramen (IVF) or spinal canal'', the oldest and most widely known of these theories, proposes that subluxations cause bulging intervertebral discs, hypertrophied facet joint capsules, or enlarged intra-foraminal ligaments that encroach on pressure-sensitive IVF contents (e.g., dorsal root ganglia, nerve roots, and associated vascular elements) or the spinal canal and its contents (spinal cord, nerve roots and vascular plexus). Narrowing of the spinal canal and intervertebral foramen has been demonstrated in association with vertebral misalignments <ref>{{cite book|last=J.W. Frymoyer, S.W. Wiesel|title=The adult and pediatric spine|year=2004|publisher=Lippincott Williams & Wilkins|location=Philadelphia}}</ref> Cadaveric and animal studies have shown that intervertebral foramen encroachment can produce sufficient pressure on neural contents to retard axoplasmic flow and the latency and amplitude of action potential transmission <ref>{{cite journal|coauthors=Y. Morishita, S. Hida, M. Naito, J. Arimizu, U. Matsushima, A. Nakamura|title=Measurement of the local pressure of the intervertebral foramen and the electrophysiologic values of the spinal nerve roots in the vertebral foramen|journal=Spine|year=2006|volume=31|issue=26|pages=3076–3080|accessdate=27 January 2013}}</ref><ref>{{cite journal|coauthors=B.A. Winkelstein, J.A. DeLeo|title=Mechanical thresholds for initiation and persistence of pain following nerve root injury: mechanical and chemical contributions at injury|journal=J Biomech Eng|year=2004|volume=126|issue=2|pages=258–263|accessdate=27 January 2013}}</ref> Vertebral canal and IVF stenosis, with encroachment upon neural structures can occur as a result of vertebral subluxation with osseous degeneration and/or soft-tissue changes; such as disc thinning and bulging; ligament laxity, fibrosis, bucking; and joint capsule hypertrophy <ref>{{cite journal|coauthors=F. Alyas, D. Connell, A. Saifuddin|title=Upright positional MRI of the lumbar spine|journal=Clinical Radiology|year=2008|volume=63|issue=9|pages=1035–1048|accessdate=27 January 2013}}</ref><ref>{{cite journal|coauthors=S. Genevay, S.J. Atlas|title=Lumbar spinal stenosis|journal=Best Pract Res Clin Rheumatol|year=2010|volume=24|issue=2|pages=253–265|accessdate=27 January 2013}}</ref> In an examination of the degenerative effects of experimentally induced intervertebral hypomobility in the rat it was observed substantial increased zygapophysial articular cartilage erosion and hypertrophic spur formation associated with hypomobile vertebrae.<ref>{{cite journal|coauthors=G.D. Cramer, J.T. Fournier, C.N.R. Henderson, C.C. Wolcott|title=Degenerative changes following spinal fixation in a small animal model|journal=JMPT|year=2004|volume=27|issue=3|pages=141–154|accessdate=27 January 2013}}</ref>
A 2010 study describing Belgian chiropractors and their patients found chiropractors in Belgium mostly focus on neuromusculoskeletal complaints in adult patients, with emphasis on the spine. The diversified technique is the most often applied technique at 93%, followed by the Activator mechanical-assisted technique at 41%.<ref>{{Cite pmid|21036284}}</ref> A 2009 study assessing chiropractic students giving or receiving spinal manipulations while attending a U.S. chiropractic college found Diversified, Gonstead, and upper cervical manipulations are frequently used methods.<ref>{{cite journal|journal=J Manipulative Physiol Ther|year=2009|volume=32|issue=2|pages=140–8|title= Prevalence of musculoskeletal injuries sustained by students while attending a chiropractic college|author= Ndetan HT, Rupert RL, Bae S, Singh KP|doi=10.1016/j.jmpt.2008.12.012|pmid=19243726}}</ref>


2. ''Altered afferent input'' from spinal and paraspinal tissues is thought to attend subluxations and produce lasting and far-reaching effects via neuroplastic changes in the peripheral and central nervous systems.This widely held chiropractic theory posits that long-term changes in intervertebral mobility or alignment provides altered afferent input to the central nervous system, causing neuroplastic changes that impact biological function <ref name="Cramer 2005 296–303"/><ref>{{cite journal|coauthors=H. Haavik-Taylor, B. Murphy|title=The effects of spinal manipulation on central integration of dual somatosensory input observed after motor training: a crossover study|journal=JMPT|year=2010|volume=33|issue=4|pages=261–272|accessdate=27 January 2013}}</ref><ref>{{cite journal|coauthors=D.R. Seaman, J.F. Winterstein|title=Dysafferentation: a novel term to describe the neuropathophysiological effects of joint complex dysfunction. A look at likely mechanisms of symptom generation|journal=JMPT|year=1998|volume=21|issue=4|pages=267–280|accessdate=27 January 2013}}</ref> This theory is generally extended to explain that spinal manipulation normalizes spine biomechanics, and as a consequence, normalizes afferent input to the central nervous system – resulting in normalized neurological function and improved health outcomes.
===Practice guidelines===
Reviews of research studies within the chiropractic community have been used to generate practice guidelines outlining standards that specify which chiropractic treatments are "legitimate" (i.e., supported by evidence) and conceivably reimbursable under [[managed care]] health payment systems.<ref name=Villanueva-Russell/> Evidence-based guidelines are supported by one end of an ideological continuum among chiropractors; the other end employs [[antiscientific]] reasoning and makes unsubstantiated claims.<ref name=History-Primer2>{{cite web|title= Chiropractic history: a primer|author= [[Joseph C. Keating, Jr.]], Cleveland CS III, Menke M|url=http://www.philosophyofchiropractic.com/primerall72.pdf|format=PDF|year=2005|accessdate=2008-06-16|publisher= Association for the History of Chiropractic|quote= A significant obstacle to progress within the chiropractic community is the range of anti-scientific and pseudo-scientific ideas (Keating 1997b) originating from the earlier history of chiropractic, and resulting tensions with [[evidence-based medicine]]. The tendency of some chiropractors to assert the meaningfulness of various theories and methods as a counterpoint to charges of "quackery" has created a defensiveness which can make critical examination of chiropractic concepts difficult (Keating and Mootz 1989). One example of this conundrum is the continuing controversy about the presumptive target of DCs' adjustive interventions: subluxation (Gatterman 1995; Leach 1994).}}{{dead link|date=June 2012}}</ref><ref name=Keating-subluxation/><ref name=Nelson>{{cite journal|journal=Chiropr Osteopat|year=2005|volume=13|page=9|title=Chiropractic as spine care: a model for the profession|author=Nelson CF, Lawrence DJ, Triano JJ ''et al.''|doi=10.1186/1746-1340-13-9|pmid=16000175|pmc=1185558|issue=1}}</ref><ref>Science, antiscience, materialism and vitalism:
*{{cite journal|author= [[Joseph C. Keating, Jr.]]|journal= [[Skept Inq]]|volume=21|issue=4|pages=37–43|title= Chiropractic: science and antiscience and pseudoscience side by side|year=1997}}
*{{cite book|author= Phillips RB|chapter= The evolution of vitalism and materialism and its impact on philosophy|pages=65–76|title= Principles and Practice of Chiropractic|edition=3rd|editor= Haldeman S, Dagenais S, Budgell B ''et al.'' (eds.)|publisher=[[McGraw-Hill]]|year=2005|isbn=0-07-137534-1}}</ref> A 2007 survey of [[Alberta]] chiropractors found that they do not consistently apply research in practice, which may have resulted from a lack of research education and skills.<ref>{{cite journal|journal= J Manipulative Physiol Ther|year=2007|volume=30|issue=2|pages=109–15|title= How important is research-based practice to chiropractors and massage therapists?|author= Suter E, Vanderheyden LC, Trojan LS, Verhoef MJ, Armitage GD|doi=10.1016/j.jmpt.2006.12.013|pmid=17320731}}</ref>


3. ''Dentate ligament mediated cord distortion'' has been proposed as a mechanism by which misaligned cervical vertebrae can directly stress sensitive brainstem and upper cervical cord structures, thereby disrupting critical neural processes. This theory is especially interesting to chiropractors that limit spinal manipulation to the upper cervical region.<ref>{{cite book|last=Eriksen|title=Upper cervical subluxation complex. A review of the chiropractic and medical literature|year=2004|publisher=ippincott Williams & Wilkins|location=Philadelphia}}</ref> Recently several investigators have reported a connective tissue bridge between the rectus capitus posterior minor (RCPm) and the spinal dura in the region of the posterior atlanto-occipital membrane <ref>{{cite journal|coauthors=B.K. Humphreys, S. Kenin, B.B. Hubbard, G.D. Cramer|title=Investigation of connective tissue attachments to the cervical spinal dura mater|journal=Clinical Anatomy|year=2003|volume=16|issue=2|pages=152–159|accessdate=27 January 2013}}</ref><ref name="ReferenceA">{{cite journal|coauthors=L. Nash, H. Nicholson, A.S. Lee, G.M. Johnson, M. Zhang|title=Configuration of the connective tissue in the posterior atlanto-occipital interspace. A sheet plastination and confocal microscopy study|journal=Spine|year=2005|volume=30|pages=1359–1366|accessdate=27 January 2013}}</ref> It has been proposed that this connective tissue bridge has two important physiological roles. It may prevent brain stem compression that could occur as a result of dural infolding during cervical flexion and extension and it may also stabilize the cranio-cervical region<ref name="ReferenceA"/> In addition, a pathophysiological role has been proposed. It is thought that RCPm mediated tension on the pain sensitive posterior cerebro-spinal dura may be a primary mechanism for the etiology of cervicogenic headache.<ref>{{cite journal|coauthors=M.E. Alix, D.K. Bates|title=A proposed etiology of cervicogenic headache: the neurophysiologic basis and anatomic relationship between the dura mater and the rectus posterior capitis minor muscle|journal=JMPT|year=1999|volume=22|issue=8|pages=534–539|accessdate=27 January 2013}}</ref>
== Education, licensing, regulation ==
Chiropractors are also interested in the reflex effects of spinal dysfunction with regards to the [[autonomic nervous system]]. recent neuroscience research supports a neurophysiologic rationale for the concept that aberrant stimulation of spinal or paraspinal structures may lead to segmentally organized reflex responses of the autonomic nervous system, which in turn may alter visceral function."<ref name=RMIT>{{cite journal |author=Budgell BS |title=Reflex effects of subluxation: the autonomic nervous system |journal=J Manipulative Physiol Ther |volume=23 |issue=2 |pages=104–6 |year=2000 |month=February |pmid=10714536 |url=http://linkinghub.elsevier.com/retrieve/pii/S0161-4754(00)90076-9 |doi=10.1016/S0161-4754(00)90076-9}}</ref>
{{Main|Chiropractic education|List of chiropractic schools}}
Requirements vary between countries. In the U.S. chiropractors obtain a [[first professional degree]] in the field of chiropractic.<ref>{{cite web|url=http://nces.ed.gov/programs/coe/glossary/f.asp|title= Glossary|publisher= National Center for Education Statistics, [[U.S. Dept. of Education]]|accessdate=2009-06-05}}{{dead link|date=June 2012}}</ref> The curriculum content of North American chiropractic and medical colleges with regard to basic and clinical sciences has been more similar than not, both in the kinds of subjects offered and in the time assigned to each subject.<ref>{{cite journal|author=Coulter I, Adams A, Coggan P, Wilkes M, Gonyea M|title= A comparative study of chiropractic and medical education.|journal=Altern Ther Health Med|volume=4|issue=5|pages=64–75|year=1998|pmid=9737032 }}</ref>


===Evidence-based practice guidelines===
Accredited chiropractic programs in the U.S. require that applicants have 90 semester hours of undergraduate education with a [[grade point average]] of at least 3.0 on a 4.0 scale. Many programs require at least three years of undergraduate education, and more are requiring a bachelor's degree.<ref>{{cite web|url=http://www.chirocolleges.org/prospective_students.html|title=Prospective students|publisher=Association of Chiropractic Colleges|accessdate=2009-07-23}}</ref> Canada requires a minimum three years of undergraduate education for applicants, and at least 4200 instructional hours (or the equivalent) of full‐time chiropractic education for matriculation through an accredited chiropractic program.<ref>{{cite web|url=http://chirofed.ca/english/pdf/Standards_for_Doctor_of_Chiropractic_Programmes.pdf|format=PDF|title=Standards for Doctor of Chiropractic Programmes|date=2008-04-05|publisher=[[Canadian Federation of Chiropractic Regulatory and Educational Accrediting Boards]]|accessdate=2009-04-23}}{{dead link|date=June 2012}}</ref>
With growing mainstream acceptance of spinal manipulation in the 1980s<ref>{{cite web |url=http://muaphysicians.com/historical.html |publisher= International MUA Academy of Physicians |title= Manipulation under anesthesia: historical considerations |author= Francis RS |date=2005 |accessdate=2008-07-06}}</ref>the 1990s resulted in a growing scholarly interest in chiropractic, which helped efforts to improve service quality and establish clinical guidelines. In the current advent of the evidence-based medicine era, chiropractic scholars have generated evidence-based systematic reviews and [[practice guidelines]] with respect to the management of acute/chronic low back pain,<ref>{{cite journal|coauthors=Farabaugh RJ, Dehen MD, Hawk C.|title=Management of chronic spine-related conditions: consensus recommendations of a multidisciplinary panel.|journal=JMPT|year=2010|month=Sept|volume=33|issue=7|pages=484-492|pmid=20937426|accessdate=8 February 2013}}</ref><ref>{{cite journal|coauthors=Globe GA, Morris CE, Whalen WM, Farabaugh RJ, Hawk C; Council on Chiropractic Guidelines and Practice Parameter.|title=Chiropractic management of low back disorders: report from a consensus process.|journal=JMPT|year=2008|month=Nov-Dec|volume=31|issue=9|pages=651-658|pmid=19028249|accessdate=8 February 2013}}</ref> thoracic pain, neck pain,<ref>{{cite journal|coauthors=Canadian Chiropractic Association; Canadian Federation of Chiropractic Regulatory Boards; Clinical Practice Guidelines Development Initiative; Guidelines Development Committee (GDC), Anderson-Peacock E, Blouin JS, Bryans R, Danis N, Furlan A, Marcoux H, Potter B, Ruegg R, Stein JG, White E.|title=Chiropractic clinical practice guideline: evidence-based treatment of adult neck pain not due to whiplash.|journal=JCCA|year=2005|month=Sept|volume=49|issue=3|pages=158-209.|pmid=17549134|accessdate=8 February 2013}}</ref> headache,<ref>{{cite journal|coauthors=Bryans R, Descarreaux M, Duranleau M, Marcoux H, Potter B, Ruegg R, Shaw L, Watkin R, White E.|title=Evidence-based guidelines for the chiropractic treatment of adults with headache.|journal=J Manipulative Physiol Ther|year=2011|month=June|volume=34|issue=5|pages=274-89|pmid=21640251|accessdate=8 February 2013}}</ref> radiography,<ref>{{cite journal|coauthors=Bussières AE, Peterson C, Taylor JA.|title=Diagnostic imaging guideline for musculoskeletal complaints in adults-an evidence-based approach-part 2: upper extremity disorders.|journal=J Manipulative Physiol Ther.|year=2008|month=January|volume=31|issue=1|pages=2-32|pmid=18308152|accessdate=8 February 2013}}</ref> <ref>{{cite journal|coauthors=Bussières AE, Taylor JA, Peterson C.|title=Diagnostic imaging practice guidelines for musculoskeletal complaints in adults-an evidence-based approach-part 3: spinal disorders.|journal=JMPT|year=2008|month=Jan|volume=31|issue=1|pages=33-88|pmid=18308153|accessdate=8 February 2013}}</ref> <ref>{{cite journal|coauthors=Bussières AE, Peterson C, Taylor JA.|title=Diagnostic imaging practice guidelines for musculoskeletal complaints in adults--an evidence-based approach: introduction.|journal=JMPT|year=2007|month=Nov-Dec|volume=30|issue=9|pages=617-83.|accessdate=8 February 2013}}</ref> and upper/lower extremity conditions.<ref>{{cite journal|coauthors=Brantingham JW, Globe G, Pollard H, Hicks M, Korporaal C, Hoskins W.|title=Manipulative therapy for lower extremity conditions: expansion of literature review.|journal=JMPT|year=2009|month=Jan|volume=32|issue=1|pages=53-71|pmid=19121464|accessdate=8 February 2013}}</ref><ref>{{cite journal|coauthors=McHardy A, Hoskins W, Pollard H, Onley R, Windsham R.|title=Chiropractic treatment of upper extremity conditions: a systematic review.|journal=JMPT|year=2008|month=Feb|volume=31|issue=2|pages=146-159|pmid=18328941|accessdate=8 February 2013}}</ref> [[tendinopathy]]<ref>{{cite journal|coauthors=Pfefer MT, Cooper SR, Uhl NL.|title=Chiropractic management of tendinopathy: a literature synthesis.|journal=JMPT|year=2009|month=Jan|volume=32|issue=1|pages=41-52|pmid=19121463|accessdate=8 February 2013}}</ref> [[myofascial]] pain/trigger points,<ref>{{cite journal|coauthors=Vernon H, Schneider M.|title=Chiropractic management of myofascial trigger points and myofascial pain syndrome: a systematic review of the literature.|journal=JMPT|year=2009|month=Jan|volume=32|issue=1|pages=14-24|pmid=19121461|accessdate=8 February 2013}}</ref> and non-musculoskeletal conditions.<ref>{{cite journal|coauthors=Hawk C, Khorsan R, Lisi AJ, Ferrance RJ, Evans MW.|title=Chiropractic care for nonmusculoskeletal conditions: a systematic review with implications for whole systems research.|journal=J Altern Complement Med.|year=2007|month=June|volume=13|issue=5|pages=491-512|pmid=17604553|accessdate=8 February 2013}}</ref>
==Treatment==
===Manual and manipulative therapy===
The medicinal use of spinal manipulation can be traced back over 3000 years to ancient Chinese writings. [[Hippocrates]], the "father of medicine" used manipulative techniques<ref name=Swedlo>{{cite conference |url=http://www.hom.ucalgary.ca/Dayspapers2002.pdf |format=PDF |booktitle= Proc 11th Annual History of Medicine Days |editor= Whitelaw WA (ed.) |title= The historical development of chiropractic |publisher= [[Faculty of Medicine, The University of Calgary]] |pages= 55–58 |author= Swedlo DC |date=2002 |accessdate=2008-05-14}}</ref> as did the ancient Egyptians and many other cultures. A modern re-emphasis on [[manipulative therapy]] occurred in the late 19th century in North America with the emergence of the [[osteopathic medicine]] and [[chiropractic medicine]].<ref name=Keating-pathways>{{cite journal |journal= J Manipulative Physiol Ther |date=2003 |volume=26 |issue=5 |pages=300–21 |title= Several pathways in the evolution of chiropractic manipulation |author= Keating JC Jr |doi=10.1016/S0161-4754(02)54125-7 |pmid=12819626}}</ref> Spinal manipulation gained mainstream recognition during the 1980s.<ref>{{cite web |url=http://muaphysicians.com/historical.html |publisher= International MUA Academy of Physicians |title= Manipulation under anesthesia: historical considerations |author= Francis RS |date=2005 |accessdate=2008-07-06}}</ref> Spinal manipulation/adjustment describes techniques where the hands are used to manipulate, [[massage]], [[mobilize]], adjust, stimulate, apply traction to, or otherwise influence the spine and related tissues.<ref name=ACA-SMP>{{cite web |url=http://acatoday.org/pdf/spinal_manipulation_policy.pdf |format=PDF |title= Spinal manipulation policy statement |author= Winkler K, Hegetschweiler-Goertz C, Jackson PS ''et al.'' |accessdate=2008-05-24 |date=2003 |publisher= American Chiropractic Association}}</ref> It is the most common and primary intervention used in chiropractic care;<ref name=NBCE_techniques>{{cite book|title= Job Analysis of Chiropractic|chapter= Professional functions and treatment procedures|year=2005|pages=121–38|author= Christensen MG, Kollasch MW|location= Greeley, CO|publisher= [[National Board of Chiropractic Examiners]]|chapterurl=http://nbce.org/pdfs/job-analysis/chapter_10.pdf|format=PDF|accessdate=2008-08-25|isbn=1-884457-05-3}}{{dead link|date=June 2012}}</ref> In North America, chiropractors perform over 90% of all manipulative treatments<ref>{{cite web |url=http://nccam.nih.gov/health/chiropractic/chiropractic05.pdf |format=PDF |title= About chiropractic and its use in treating low-back pain |accessdate=2008-03-24 |date=2005 |publisher=[[NCCAM]] |archiveurl = http://web.archive.org/web/20080227113930/http://nccam.nih.gov/health/chiropractic/chiropractic05.pdf <!-- Bot retrieved archive --> |archivedate = 2008-02-27}}</ref> with the balance provided by [[osteopathic medicine]], [[physical therapy]] and [[naturopathic medicine]]. [[Manipulation under anesthesia]] or MUA is a specialized manipulative procedure that typically occurs in hospitals administered under general anesthesia.<ref>{{cite journal |journal= J Manipulative Physiol Ther |date=2005 |volume=28 |issue=7 |pages=526–33 |title= Manipulation under anesthesia: a report of four cases |author= Cremata E, Collins S, Clauson W, Solinger AB, Roberts ES |doi=10.1016/j.jmpt.2005.07.011 |pmid=16182028}}</ref> Typically, it is performed on patients who have failed to respond to other forms of treatment.<ref>{{cite journal |journal=J Manipulative Physiol Ther |date=2000 |volume=23 |issue=2 |pages=127–9 |title=Manipulation under joint anesthesia/analgesia: a proposed interdisciplinary treatment approach for recalcitrant spinal axis pain of synovial joint origin |author=Michaelsen MR |doi=10.1016/S0161-4754(00)90082-4 |pmid=10714542 |url=http://www.jmptonline.org/article/S0161-4754(00)90082-4/abstract}}</ref>There has been considerable debate on the safety of spinal manipulation, in particular with the cervical spine.<ref name=Ernst-adverse>{{cite journal |pmid=17606755 |doi=10.1258/jrsm.100.7.330 |laysummary=http://www.medicalnewstoday.com/articles/75754.php |laysource=Med News Today |laydate=2 July 2007 |year=2007 |month=Jul |last1=Ernst |first1=E |title=Adverse effects of spinal manipulation: a systematic review |volume=100 |issue=7 |pages=330–8 |issn=0141-0768 |journal=Journal of the Royal Society of Medicine |pmc=1905885}}</ref> Although serious injuries and fatal consequences can occur and may be under-reported,<ref name=Ernst-death>{{cite journal |journal= Int J Clinical Practice |year=2010 |volume=64 |issue= 8 |pages=1162–1165 |title= Deaths after chiropractic: a review of published cases |author= E Ernst |pmid=20642715 |doi=10.1111/j.1742-1241.2010.02352.x}}</ref> these are generally considered to be rare when spinal manipulation is employed skillfully and appropriately.<ref name=WHO-guidelines/>


===Definitions ===
CCEs in the U.S., Canada, Australia and Europe have joined to form CCE-International (CCE-I) as a model of accreditation standards with the goal of having credentials portable internationally.<ref name=CCEI>{{cite web| url = http://www.cceintl.org/About_Us.html| title = About Us| accessdate = 2010-09-30| publisher = [[Councils on Chiropractic Education International]]}}</ref> Today, there are 18 accredited Doctor of Chiropractic programs in the U.S.,<ref>{{cite web|title=Accredited Doctor of Chiropractic programs|url=http://cce-usa.org/adcp.php|publisher=The Council on Chiropractic Education|accessdate=2008-02-22|archiveurl = http://web.archive.org/web/20080214031937/http://www.cce-usa.org/adcp.php|archivedate = 2008-02-14}}</ref> 2 in Canada,<ref>{{cite web|url=http://chirofed.ca/english/accreditation.html|title=Accreditation of educational programmes|publisher=Canadian Federation of Chiropractic Regulatory and Educational Accrediting Boards|accessdate=2009-06-05 }}</ref> 6 in Australasia,<ref name=CCEA>{{cite web| url = http://www.ccea.com.au/Accreditation/Program%20Accreditation%20Status.htm| title = Program Accreditation Status| accessdate = 2010-09-30| publisher = Council on Chiropractic Education Australasia}}</ref> and 5 in Europe.<ref>{{cite web|url=http://cce-europe.org/institutions.php|title=Institutions holding ''Accredited Status'' with the ECCE|publisher=[[European Council On Chiropractic Education]]|date=2009-07-23|accessdate=2009-07-25 }}{{dead link|date=June 2012}}</ref>
High-velocity low amplitude (HVLA) manipulative therapy is also known as 'adjustment' and Grade V mobilisation<ref>Maitland, G.D. ''Peripheral Manipulation'' 2nd ed. Butterworths, London, 1977.<br>
Maitland, G.D. ''Vertebral Manipulation'' 5th ed. Butterworths, London, 1986.</ref>


===Categories===
Regulatory colleges and chiropractic boards in the U.S., Canada, Mexico, and Australia are responsible for protecting the public, standards of practice, disciplinary issues, quality assurance and maintenance of competency.<ref>{{cite web| url = http://www.chiropracticcanada.ca/en-us/FactsFAQs.aspx| title = Canadian Chiropractic Association FAQs| accessdate = 2010-10-02| publisher = [[Canadian Chiropractic Association]]}}{{dead link|date=January 2013}}</ref><ref>{{cite web| url = http://pacex.fclb.org/Information/FAQ/tabid/364/Default.aspx| title = Federation of Chiropractic Licensing Boards FAQ| accessdate = 2010-10-02| publisher = [[Federation of Chiropractic Licensing Boards]]}}</ref> There are an estimated 49,000 chiropractors in the U.S. (2008),<ref name=BLS/> 6,500 in Canada (2010),<ref>{{cite web| url = http://www.chiropracticcanada.ca/en-us/AboutUs/ChiropracticInCanada.aspx| title = Canadian Chiropractic Association: Chiropractic in Canada| accessdate = 2010-10-02| publisher = [[Canadian Chiropractic Association]]}}</ref> 2,500 in Australia (2000),<ref name=Campbell/> and 1,500 in the UK (2000).<ref>{{cite book|title= The Chiropractic Profession: Its Education, Practice, Research and Future Directions|author= Chapman-Smith D|year=2000|chapter= Current status of the profession|isbn=1-892734-02-8|publisher=[[NCMIC]]|location= West Des Moines, IA}}</ref>
Manual and manipulative techniques can be categorized by different modes depending on therapeutic intent, indications, contraindications and safety.<ref name=CCA>[http://www.ccachiro.org/client/cca/cca.nsf/web/Chapter+10+-+Modes+Of+Care+And+Management!OpenDocument Chapter 10 - Modes Of Care And Management.] Canadian Chiropractic Association</ref> Manual and mechanically-assisted articular manipulative procedures can include:


*HVLA thrust manipulation
A 2008 commentary proposed that the chiropractic profession actively regulate itself to combat abuse, fraud and [[quackery]], which are more prevalent in chiropractic than in other health care professions, violating the [[social contract]] between patients and physicians.<ref name=Murphy-pod/>
*HVLA thrust manipulation with recoil
*LVLA manipulation (mobilization)
*Drop tables and terminal point manipulative thrust
*Flexion-distraction and traction-type tables
*Pelvic blocks
*Instrument assisted manipulative devices


Manual non-articular manipulative procedures can include:
==International reception==
*Reflex and muscle relaxation procedures
{{globalize|section|North America|date=December 2012}}
*Muscle energy techniques
*Myofascial ischemic compression procedures
*Myofascial, and soft tissue manipulative techniques
===Musculoskeletal disorders===
[[Image:Manuellterapi5.jpg|right|450px|thumb|]]
The use of manual and manipulative therapies is a commonly used intervention used by manual medicine practitioners in the treatment of neuromusculoskeletal disorders. Spinal manipulation, in particular, is widely seen as a reasonable treatment option for biomechanical disorders of the spine, such as neck pain and low back pain<ref name="smt and visceral responses">{{cite journal|coauthors=Bolton PS, Budgell B.|title=Visceral responses to spinal manipulation|journal=J Electromyogr Kinesiol.|year=2012|month=Oct|volume=22|issue=5|pages=777-84.|pmid=22440554|accessdate=10 February 2013}}</ref> Manual therapies, including spinal manipulation, commonly used by chiropractors and other manual medicine practitioners are effective for the treatment of spinal pain, including low back pain, neck pain, some forms of headache and a number of extremity joint conditions such as shoulder and hip pain. Specifically, spinal manipulation/mobilization is effective in adults for: acute, subacute, and chronic low back pain; migraine and cervicogenic headache; cervicogenic dizziness; manipulation/mobilization is effective for several extremity joint conditions; and thoracic manipulation/mobilization is effective for acute/subacute neck pain<ref name=Bronfort-Haas>{{cite journal|journal= Chiropractic & Osteopathy|year=2010|volume=18|issue=3|title= Effectiveness of manual therapies: the UK evidence report|author= Bronfort G, Haas M, Evans R, Leininger B, Triano J|doi=10.1186/1746-1340-18-3|pmid=20184717|url=http://chiromt.com/content/18/1/3|pmc=2841070|page= 3}}</ref>and might also be effective for the treatment of lumbar disc herniation with radiculopathy,<ref name="Leininger B, Bronfort G, Evans R, Reiter T 2011 105–25">{{cite journal|journal= Phys Med Rehabil Clin N Am|year=2011|volume=22|issue=1|pages=105–25|title= Spinal manipulation or mobilization for radiculopathy: a systematic review|author= Leininger B, Bronfort G, Evans R, Reiter T|pmid=21292148|doi=10.1016/j.pmr.2010.11.002}}</ref><ref name="Hahne AJ, Ford JJ, McMeeken JM 2010 E488–504">{{cite journal|journal= Spine|year=2010|volume=35|issue=11|pages=E488–504|title= Conservative management of lumbar disc herniation with associated radiculopathy: a systematic review|author= Hahne AJ, Ford JJ, McMeeken JM|pmid=20421859|doi=10.1097/BRS.0b013e3181cc3f56}}</ref> neck pain,<ref name="Gross A, Miller J, D'Sylva J, Burnie SJ, Goldsmith CH, Graham N, Haines T, Brønfort G, Hoving JL 2010 315–333">{{cite journal|journal= Manual Therapy|year= 2010|volume=15|issue=4|pages=315–333|title= Manipulation or mobilisation for neck pain: a Cochrane Review|author= Gross A, Miller J, D'Sylva J, Burnie SJ, Goldsmith CH, Graham N, Haines T, Brønfort G, Hoving JL|pmid=20510644|doi= 10.1016/j.math.2010.04.002 }}</ref> some forms of headache,<ref name="Chaibi A, Tuchin PJ, Russell MB 2011">{{cite journal|journal= J Headache Pain|year=2011|volume= 12|issue= 2|pages= 127–33|title= Manual therapies for migraine: a systematic review|author= Chaibi A, Tuchin PJ, Russell MB|pmid=21298314|doi=10.1007/s10194-011-0296-6|pmc=3072494}}</ref><ref name="Bronfort G, Nilsson N, Haas M et al. 2004 CD001878">{{cite journal|journal= Cochrane Database Syst Rev|year=2004|issue=3|pages=CD001878|title= Non-invasive physical treatments for chronic/recurrent headache|author= Bronfort G, Nilsson N, Haas M ''et al.''|doi=10.1002/14651858.CD001878.pub2|pmid=15266458|editor1-last= Brønfort|editor1-first= Gert}}</ref> and some extremity joint conditions.<ref name="Brantingham JW, Globe G, Pollard H, Hicks M, Korporaal C, Hoskins W 2009 53–71">{{cite journal|author= Brantingham JW, Globe G, Pollard H, Hicks M, Korporaal C, Hoskins W|title= Manipulative therapy for lower extremity conditions: expansion of literature review|journal= J Manipulative Physiol Ther|volume=32|issue=1|pages=53–71|year=2009|pmid=19121464|doi=10.1016/j.jmpt.2008.09.013}}</ref><ref name="pmid21109059">{{Cite pmid|21109059}}</ref>


Investigation of the effectiveness of spinal manipulation for specific musculoskeletal complaints include:
;Australia


*'''[[Low back pain]]'''. Most studies suggest spinal manipulation achieves equivalent or superior improvement in pain and function when compared with other commonly used interventions for short, intermediate, and long-term follow-up.<ref name=Dagenais-2010>{{cite journal|journal= [[Spine J]]|year=2010|volume=10|issue=10|pages=918–940|title= NASS Contemporary Concepts in Spine Care: Spinal manipulation therapy for acute low back pain|author= Dagenais S, Gay RE, Tricco AC, Freeman MD, Mayer JM|doi=10.1016/j.spinee.2010.07.389|pmid=20869008}}</ref> A 2008 review found strong evidence that SM is similar in effect to medical care with exercise.<ref name=Bronfort-2008>{{cite journal|journal= [[Spine J]]|year=2008|volume=8|issue=1|pages=213–25|title= Evidence-informed management of chronic low back pain with spinal manipulation and mobilization|author= Bronfort G, Haas M, Evans R, Kawchuk G, Dagenais S|doi=10.1016/j.spinee.2007.10.023|pmid=18164469}}</ref> A 2008 literature synthesis found good evidence supporting SM for low back pain regardless of duration.<ref name=Lawrence-2008>{{cite journal|title= Chiropractic management of low back pain and low back-related leg complaints: a literature synthesis|author= Lawrence DJ, Meeker W, Branson R ''et al.''|journal= J Manipulative Physiol Ther|volume=31|issue=9|pages=659–74|year=2008|pmid=19028250|doi=10.1016/j.jmpt.2008.10.007}} An earlier, freely readable version is in: {{cite web|title= Chiropractic management of low back pain and low back related leg complaints|author= Meeker W, Branson R, Bronfort G ''et al.''|url=http://ccgpp.org/lowbackliterature.pdf|format=PDF|year=2007|accessdate=2008-11-28|publisher= [[Council on Chiropractic Guidelines and Practice Parameters]]}}</ref> The [[American College of Physicians]] and the [[American Pain Society]] jointly recommended that clinicians consider spinal manipulation for patients who do not improve with self care options.<ref>{{cite journal |journal= Ann Intern Med |date= October 2, 2007 |volume=147 |issue=7 |pages=478–91 |title= Diagnosis and treatment of low back pain: a joint clinical practice guideline from the American College of Physicians and the American Pain Society |author= Chou R |pmid=17909209 |url=http://annals.org/cgi/content/full/147/7/478 |author-separator= , |author2= Qaseem A |author3= Snow V |display-authors= 3 |last4= Casey |first4= D |last5= Cross Jr |first5= JT |last6= Shekelle |first6= P |last7= Owens |first7= DK |author8= Clinical Efficacy Assessment Subcommittee of the American College of Physicians |last9= American College Of |first9= Physicians |doi=10.7326/0003-4819-147-7-200710020-00006}}</ref>
In Australia, most private health insurance funds cover chiropractic care, and the federal government funds chiropractic care when the patient is referred by a medical practitioner.<ref>{{cite journal|journal= BMC Public Health|year=2008|volume=8|page=105|title= Acupuncture, chiropractic and osteopathy use in Australia: a national population survey|author= Xue CC, Zhang AL, Lin V, Myers R, Polus B, Story DF|doi=10.1186/1471-2458-8-105|pmid=18377663|url=http://www.biomedcentral.com/1471-2458/8/105|pmc= 2322980}}</ref>
* '''[[Radiculopathy]]'''. There is moderate quality evidence to support the use of spinal manipulation for the treatment of acute [[Sciatica|lumbar radiculopathy]]<ref name="Leininger B, Bronfort G, Evans R, Reiter T 2011 105–25"/> and acute lumbar [[disc herniation]] with associated radiculopathy.<ref name="Hahne AJ, Ford JJ, McMeeken JM 2010 E488–504"/> The evidence for chronic lumbar spine-related extremity symptoms and cervical spine-related extremity symptoms of any duration is low or very low and no evidence exists for the treatment of thoracic radiculopathy.<ref name="Leininger B, Bronfort G, Evans R, Reiter T 2011 105–25"/>
* '''[[Neck pain]]'''. Manual therapies, including spinal manipulation, has been found to be effective for mechanical neck pain.<ref name=Bronfort-Haas>{{cite journal|journal= Chiropractic & Osteopathy|year=2010|volume=18|issue=3|title= Effectiveness of manual therapies: the UK evidence report|author= Bronfort G, Haas M, Evans R, Leininger B, Triano J|doi=10.1186/1746-1340-18-3|pmid=20184717|url=http://chiromt.com/content/18/1/3|pmc=2841070|page= 3}}</ref> <ref>{{cite journal|coauthors=Hurwitz EL, Carragee EJ, van der Velde G, Carroll LJ, Nordin M, Guzman J, Peloso PM, Holm LW, Côté P, Hogg-Johnson S, Cassidy JD, Haldeman S; Bone and Joint Decade 2000-2010 Task Force on Neck Pain and Its Associated Disorders.|title=Treatment of neck pain: noninvasive interventions: results of the Bone and Joint Decade 2000-2010 Task Force on Neck Pain and Its Associated Disorders.|journal=Spine|year=2008|month=Feb|volume=33|issue=4|pages=123-152|pmid=18204386|accessdate=9 February 2013}}</ref><ref name=Vernon>{{cite journal|journal= [[Eura Medicophys]]|year=2007|volume=43|issue=1|pages=91–118|title= Manual therapy for neck pain: an overview of randomized clinical trials and systematic reviews|author= Vernon H, Humphreys BK|pmid=17369783|url=http://www.minervamedica.it/en/getfreepdf.php?cod=R33Y2007N01A0091|format=PDF}}</ref><ref name=Hurwitz-2008/><ref name=CCA-CFCREAB-CPG/> Thoracic spinal manipulation (TSM) has a therapeutic benefit to some patients with neck pain and therefore TSM or in combination with other interventions is a suitable intervention to use in the treatment of non-specific neck pain.<ref>{{cite journal|coauthors=Huisman PA, Speksnijder CM, de Wijer A.|title=The effect of thoracic spine manipulation on pain and disability in patients with non-specific neck pain: a systematic review.|journal=Disabil Rehabil.|year=2013|month=Jan|pmid=23339721|accessdate=26 January 2013}}</ref>
* '''[[Headache]]''' Spinal manipulation improves migraine and cervicogenic headaches but cautioned type, frequency, dosage, and duration of treatments should be based on guideline recommendations, clinical experience, and findings. Evidence for the use of spinal manipulation as an isolated intervention for patients with tension-type headache remains equivocal.<ref>{{cite journal|coauthors=Bryans R, Descarreaux M, Duranleau M, Marcoux H, Potter B, Ruegg R, Shaw L, Watkin R, White E.|title=Evidence-based guidelines for the chiropractic treatment of adults with headache.|journal=J Manipulative Physiol Ther.|year=2011|month=June|volume=34(5)|issue=5|pages=274-89|pmid=21640251|accessdate=9 February 2013}}</ref> SM might be as effective as [[propranolol]] or [[topiramate]] in the prevention of [[migraine headache]]s,<ref name="Chaibi A, Tuchin PJ, Russell MB 2011"/>
*'''Cervicogenic dizziness''' There is moderate evidence to support the use of manual therapy for cervicogenic dizziness.<ref>{{cite journal|journal=Chiropractic and Manual Therapies|year=2011|volume=19|issue= 1|page=21|title= Manual therapy with and without vestibular rehabilitation for cervicogenic dizziness: a systematic review|author= Lystad RP, Bell G, Bonnevie-Svendsen M, Carter CV|url=http://chiromt.com/content/19/1/21/abstract|doi=10.1186/2045-709X-19-21|pmid=21923933|pmc=3182131 }}</ref>
* '''Extremity conditions'''. Manual mobilizations to an exercise program for the treatment of knee osteoarthritis resulted in better pain relief then a supervised exercise program alone and suggested that manual therapists consider adding manual mobilisation to optimise supervised active exercise programs.<ref>{{cite journal|author= Jansen MJ, Viechtbauer W, Lenssen AF, Hendriks EJ, de Bie RA|title= Strength training alone, exercise therapy alone, and exercise therapy with passive manual mobilisation each reduce pain and disability in people with knee osteoarthritis: a systematic review|journal= J Physiother|volume=57|issue=1|pages=11–20|year=2011|pmid=21402325|doi=10.1016/S1836-9553(11)70002-9}}</ref> There is silver level evidence that manual therapy is more effective than exercise for the treatment of hip osteoarthritis, however this evidence could be considered to be inconclusive.<ref>{{cite journal|journal= Man Ther|year=2011|volume=16|issue=2|pages=109–117|title= Manual therapy for osteoarthritis of the hip or knee - a systematic review|author= French HP, Brennan A, White B, Cusack T|doi= 10.1016/j.math.2010.10.011|pmid=21146444}}</ref> The addition of cervical spine mobilization to a treatment regimen for lateral epicondylosis ([[tennis elbow]]) result in significantly better pain relief and functional improvements in both the short and long-term.<ref>{{cite journal|journal= Journal of Manual & Manipulative Therapy|year=2008|volume=16|issue=4|pages=225–37|title= A Systematic Review of the Effectiveness of Manipulative Therapy in Treating Lateral Epicondylalgia|author= Herd CR, Meserve BB.|doi= 10.1179/106698108790818288|pmid=19771195|pmc= 2716156}}</ref> There is a small amount of research into the efficacy of chiropractic treatment for [[upper limb]]s,<ref>{{cite journal|journal= J Manipulative Physiol Ther|year=2008|volume=31|issue=2|pages=146–59|title= Chiropractic treatment of upper extremity conditions: a systematic review|author= McHardy A, Hoskins W, Pollard H, Onley R, Windsham R|doi=10.1016/j.jmpt.2007.12.004|pmid=18328941}}</ref> limited to low level evidence supporting chiropractic management of [[shoulder pain]]<ref name="pmid21109059"/> and limited or fair evidence supporting chiropractic management of [[human leg|leg]] conditions.<ref name="Brantingham JW, Globe G, Pollard H, Hicks M, Korporaal C, Hoskins W 2009 53–71"/>


===Non-musculoskeletal disorders===
;United Kingdom
The evidence is inconclusive for cervical manipulation/mobilization alone for neck pain of any duration, and for manipulation/mobilization for mid back pain, sciatica, tension-type headache, coccydynia, temporomandibular joint disorders, fibromyalgia, premenstrual syndrome, and pneumonia in older adults. Spinal manipulation is not effective for asthma and dysmenorrhea when compared to sham manipulation, or for Stage 1 hypertension when added to an antihypertensive diet. In children, the evidence is inconclusive regarding the effectiveness for otitis media and enuresis, and it is not effective for infantile colic and asthma when compared to sham manipulation.Massage is effective in adults for chronic low back pain and chronic neck pain. The evidence is inconclusive for knee osteoarthritis, fibromyalgia, myofascial pain syndrome, migraine headache, and premenstrual syndrome. In children, the evidence is inconclusive for asthma and infantile colic.<ref name=Bronfort-Haas>{{cite journal|journal= Chiropractic & Osteopathy|year=2010|volume=18|issue=3|title= Effectiveness of manual therapies: the UK evidence report|author= Bronfort G, Haas M, Evans R, Leininger B, Triano J|doi=10.1186/1746-1340-18-3|pmid=20184717|url=http://chiromt.com/content/18/1/3|pmc=2841070|page= 3}}</ref>

<ref>{{cite journal|journal=Spine|year=2007|volume=32|issue= 19 Suppl|pages=S130–4|title= A systematic literature review of nonsurgical treatment in adult scoliosis|author= Everett CR, Patel RK|doi=10.1097/BRS.0b013e318134ea88|pmid=17728680}}</ref> and no scientific data for [[idiopathic]] adolescent scoliosis.<ref>{{cite journal|journal=[[Scoliosis (journal)|Scoliosis]]|year=2008|volume=3|page=2|title= Manual therapy as a conservative treatment for adolescent idiopathic scoliosis: a systematic review|author= Romano M, Negrini S|doi=10.1186/1748-7161-3-2|pmid=18211702|url=http://scoliosisjournal.com/content/3/1/2|pmc=2262872|issue=1}}</ref>
A 2010 questionnaire presented to UK chiropractors indicated only 45% of chiropractors disclosed with patients the serious risk associated with manipulation of the cervical spine as a direct consequence of the fear that the patient would refuse treatment despite knowing the moral responsibility.<ref>{{Cite pmid|20977721}}</ref>

;United States and Canada

The percentage of the population that utilizes chiropractic care at any given time generally falls into a range from 6% to 12% in the U.S. and Canada,<ref name=Lawrence-Meeker/> with a global high of 20% in [[Alberta]].<ref>{{cite journal|url=http://chiroweb.com/archives/25/06/02.html|title= Chiropractic in Alberta: a model of consumer utilization and satisfaction|journal=Dyn Chiropr|volume=25|issue=6|author=Crownfield PW|year=2007}}</ref>

Chiropractors are the most common CAM providers for children and adolescents, who consume up to 14% of all visits to chiropractors.<ref name=Kemper/> The vast majority who seek chiropractic care do so for relief from back and neck pain and other neuromusculoskeletal complaints;<ref>{{cite journal|journal= [[BMC Health Serv Res]]|year=2006|volume=6|issue=49|title= A comparative analysis of chiropractic and general practitioner patients in North America: Findings from the joint Canada/United States survey of health, 2002–03|author= Hurwitz EL, Chiang LM|doi=10.1186/1472-6963-6-49|pmid=16600038|url=http://www.biomedcentral.com/1472-6963/6/49|page=49|pmc= 1458338}}</ref> most do so specifically for low back pain.<!--<ref name=Lawrence-Meeker/> -->

The largest chiropractic associations in the U.S. and Canada distributed patient brochures which contained unsubstantiated claims.<ref>{{cite journal|author=Grod JP, Sikorski D, Keating JC|title=Unsubstantiated claims in patient brochures from the largest state, provincial, and national chiropractic associations and research agencies|journal=J Manipulative Physiol Ther|volume=24|issue=8|pages=514–9|year=2001|pmid=11677551|doi=10.1067/mmt.2001.118205 }}</ref>

In the U.S., chiropractic is the largest alternative medical profession and chiropractors perform over 90% of all manipulative treatments.<ref name=shekelle>{{cite journal|journal=Ann Intern Med|year=1992|volume=117|title=Spinal manipulation for low-back pain|author=Shekelle PG, Adams AH, Chassin MR, Hurwitz EL, Brook RH|pmid=1388006|pages=590–598|issue=7}}</ref> In studies examining back pain treatments, satisfaction rates among chiropractic patients are typically higher than among medical patients.<ref name=Hertzman>{{cite journal|journal= Am J Public Health |year=2002 |volume=92 |issue=10 |pages=1628–1633 |title=Comparing the Satisfaction of Low Back Pain Patients Randomized to Receive Medical or Chiropractic Care: Results From the UCLA Low-Back Pain Study |author=Hertzman-Miller RP, Morgenstern H, Hurwitz EL, Yu F, Adams AH, Harber P, Kominski GF.|doi= 10.2105/AJPH.92.10.1628|pmid=12356612|pmc= 1447298}}</ref><ref name=Cherkin>{{cite journal|journal= West J Med |year=1989 |volume=150 |issue=3 |pages=351–355 |title= Patient evaluations of low back pain care from family physicians and chiropractors |author=Cherkin DC, MacCornack FA | doi= |pmid=2525303|pmc= 1026476}}</ref><ref name=Carey>{{cite journal|journal= N Engl J Med |year=1995 |volume=333 |issue=14 |pages=913–917 |title= The outcomes and costs of care for acute low back pain among patients seen by primary care practitioners, chiropractors, and orthopedic surgeons. The North Carolina Back Pain Project |author=Carey TS, Garrett J, Jackman A, McLaughlin C, Fryer J, Smucker DR | doi= 10.1056/NEJM199510053331406|pmid=7666878}}</ref> Treatment outcomes are not necessarily better for chiropractic patients than for medical patients;<ref name="Carey"/> the higher satisfaction among chiropractic patients is typically attributed to better communication of advice and information.<ref name=Hertzman/><ref name=Cherkin/><ref name=Carey/> Practitioners such as chiropractors are often used as a complementary form of care to primary medical intervention.<ref name=Lawrence-Meeker>{{cite journal|journal=Chiropr Osteopat|year=2007|volume=15|title=Chiropractic and CAM Utilization: A Descriptive Review|author= Lawrence DJ, Meeker WC|doi=10.1186/1746-1340-15-2|pmid=17241465|url=http://chiroandosteo.com/content/15/1/2|page=2|pmc=1784103|issue=1}}</ref>

Chiropractic is viewed as a marginal healthcare profession.<ref name="V-H"/> Public perception of chiropractic compares unfavorably with mainstream medicine with regard to ethics and honesty: in a 2006 [[Gallup Poll]] of U.S. adults, chiropractors rated last among seven health care professions for level of honesty and ethical standards, with 36% of poll respondents rating chiropractors very high or high; the corresponding ratings for the other professions ranged from 62% for dentists to 84% for nurses.<ref name=Murphy-pod/><ref>{{cite journal|journal=Dyn Chiropr|volume=25|issue=3|year=2007|title= Gallup Poll: Americans have low opinion of chiropractors' honesty and ethics|url=http://dynamicchiropractic.com/mpacms/dc/article.php?id=52038}}</ref><ref>{{cite news|title=USA TODAY/Gallup poll|url=http://usatoday.com/news/polls/tables/live/2006-12-11-ethics.htm|work=USA Today|date=2006-12-11}}</ref>

The 2008 book ''[[Trick or Treatment]]'' states that chiropractors, especially in America, have a reputation for unnecessarily treating patients, and in many circumstances the focus seems to be put on economics instead of health care.<ref name=Trick-or-Treatment>{{cite book|pages=145–90|chapter=The truth about chiropractic therapy|title=Trick or Treatment: The Undeniable Facts about Alternative Medicine|author=Singh S, Ernst E|year=2008|publisher=W.W. Norton|isbn=978-0-393-06661-6 }}</ref> Many chiropractors have sought to address their minor status within the U.S. medical community by attending practice-building seminars to assist chiropractors to persuade their patients of the efficacy of their treatments, increase their revenue, and boost their morale as unorthodox medical practitioners.<ref>{{cite journal|title=Practice-building seminars in chiropractic: a petit bourgeois response to biomedical domination|author=Baer HA|journal=Med Anthropol Q|year=1996|volume=10|issue=1|pages=29–44|pmid=8689442|doi=10.1525/maq.1996.10.1.02a00050 }}</ref> Unsubstantiated claims about the efficacy of chiropractic have continued to be made by individual chiropractors and chiropractic associations.<ref name=Ernst-eval/>

Utilization of chiropractic care is sensitive to the costs incurred by the co-payment by the patient.<ref name=Chapman-Smith>{{cite book|author= Chapman-Smith DA, Cleveland CS III|chapter= International status, standards, and education of the chiropractic profession|pages=111–34|title= Principles and Practice of Chiropractic|edition=3rd|editor= Haldeman S, Dagenais S, Budgell B ''et al.'' (eds.)|publisher=McGraw-Hill|year=2005|isbn=0-07-137534-1}}</ref> The use of chiropractic declined from 9.9% of U.S. adults in 1997 to 7.4% in 2002; this was the largest relative decrease among CAM professions, which overall had a stable use rate.<ref>{{cite journal|author= Tindle HA, Davis RB, Phillips RS, Eisenberg DM|title= Trends in use of complementary and alternative medicine by US adults: 1997–2002|journal= Altern Ther Health Med|volume=11|issue=1|pages=42–9|year=2005|pmid=15712765}}</ref> As of 2007 only 7% of the U.S. population is being reached by chiropractic.<ref>{{cite journal|journal= Dyn Chiropr|volume=25|issue=19|year=2007|author=Stanley, G.|title= The Sustainability of Chiropractic|url=http://www.dynamicchiropractic.com/mpacms/dc/article.php?id=52341 }}</ref> Employment of U.S. chiropractors is expected to increase 14% between 2006 and 2016, faster than the average for all occupations.<ref name=BLS>{{cite web|url=http://www.bls.gov/oco/ocos071.htm|title=Chiropractors|publisher= [[U.S. Bureau of Labor Statistics]]|accessdate=2008-07-05|year=2007}}</ref>

In the U.S., most states require insurers to cover chiropractic care, and most [[HMO]]s cover these services.<ref name=Kemper>{{cite journal|author= Kemper KJ, Vohra S, Walls R; Task Force on Complementary and Alternative Medicine; the Provisional Section on Complementary, Holistic, and Integrative Medicine|title= The use of complementary and alternative medicine in pediatrics|journal=Pediatrics|volume=122|issue=6|pages=1374–86|year=2008|pmid=19047261|doi=10.1542/peds.2008-2173|last5= Provisional Section On Complementary}}</ref> In Canada, there is lack of coverage under the universal public health insurance system.<ref>{{cite journal|journal= Explore (NY)|year=2008|volume=4|issue=1|pages=18–24|title= Developing integrative primary healthcare delivery: adding a chiropractor to the team|author= Garner MJ, Birmingham M, Aker P|doi=10.1016/j.explore.2007.10.003|pmid=18194787}}</ref>

==History==
{{Main|Chiropractic history|Chiropractic controversy and criticism}}
[[Image:Daniel David Palmer.jpg|thumb|upright|alt=Half-length sitting portrait of man in his fifties with large gray beard and moustache, wearing coat and vest|[[Daniel David Palmer|D.D. Palmer]]]]
Chiropractic was founded in 1895 by [[Daniel David Palmer|Daniel David (D.D.) Palmer]] in [[Davenport, Iowa]]. Palmer, a [[Magnetic healing|magnetic healer]], hypothesized that manual manipulation of the spine could cure disease.<ref name=Baer>{{cite journal|journal=Med Anthropol Q|year=1987|volume=1|issue=2|pages=176–93|title=Divergence and convergence in two systems of manual medicine: osteopathy and chiropractic in the United States|author=Baer HA|doi=10.1525/maq.1987.1.2.02a00030 }}</ref> Although initially keeping chiropractic a family secret, in 1898 Palmer began teaching it to a few students at his new [[Palmer School of Chiropractic]]. One student, his son [[Bartlett Joshua Palmer|Bartlett Joshua (B.J.) Palmer]], became committed to promoting chiropractic, took over the Palmer School in 1906, and rapidly expanded its enrollment.<ref name=Martin>{{cite journal|journal=Technol Cult|author=Martin SC|year=1993|volume=34|issue=4|pages=808–34|title=Chiropractic and the social context of medical technology, 1895–1925|doi=10.2307/3106416|pmid=11623404|jstor=3106416}}</ref>

Early chiropractors believed that all disease was caused by interruptions in the flow of [[innate intelligence]], a [[Vitalism|vital]] nervous energy or life force that represented God's presence in man; chiropractic leaders often invoked religious imagery and moral traditions. D.D. and B.J. both seriously considered declaring chiropractic a religion, which might have provided [[Free Exercise Clause of the First Amendment|legal protection under the U.S. constitution]], but decided against it partly to avoid confusion with [[Christian Science]].<ref name=Martin/><ref>{{cite web|url=http://chiro.org/Plus/History/Persons/PalmerDD/PalmerDD's_Religion-of-Chiro.pdf|format=PDF|author= Palmer DD|title= D.D. Palmer's Religion of Chiropractic: Letter to P.W. Johnson, D.C|date=1911-05-04|accessdate=2008-06-29}}</ref> Early chiropractors also tapped into the [[Populism|Populist]] movement, emphasizing craft, hard work, competition, and advertisement, aligning themselves with the common man against intellectuals and [[Trust (19th century)|trusts]], among which they included the [[American Medical Association]] (AMA).<ref name=Martin/>

A longstanding feud between chiropractors and [[medical doctor]]s continued for decades. The AMA labeled chiropractic an "unscientific [[cult]]" in 1966,<ref name=Chiro-PH>{{cite journal|journal= J Manipulative Physiol Ther|year=2008|volume=31|issue=6|pages=397–410|title= Chiropractic and public health: current state and future vision|author= Johnson C, Baird R, Dougherty PE ''et al.''|doi=10.1016/j.jmpt.2008.07.001|pmid=18722194|url=http://jmptonline.org/article/PIIS0161475408001784/fulltext}}</ref> and until 1980 advised its members that it was unethical for medical doctors to associate with "unscientific practitioners".<ref>{{cite journal|journal= [[Am J Public Health]]|year=1989|volume=79|issue=11|pages=1569–70|title= AMA policy on chiropractic|author= Cherkin D|pmid=2817179|pmc=1349822|doi= 10.2105/AJPH.79.11.1569-a}}</ref> This culminated in a landmark 1987 decision, [[Wilk v. American Medical Association|''Wilk v. AMA'']], in which the court found that the AMA had engaged in unreasonable restraint of trade and conspiracy, and which ended the AMA's de facto boycott of chiropractic.<ref name=Cooper/> In 2008 and 2009, chiropractors, including the [[British Chiropractic Association]], used [[libel]] lawsuits and threats of lawsuits against their critics,<ref>{{cite journal|author=Godlee F|title=Keep libel laws out of science|journal=BMJ|volume=339|pages=b2783|year=2009|url=http://www.bmj.com/cgi/content/full/339/jul08_4/b2783|doi=10.1136/bmj.b2783 }}</ref> however, a libel case against science writer [[Simon Singh]] ended with the BCA withdrawing its suit in 2010.<ref>{{cite news|title=Case dropped against Simon Singh|author=Pallab Ghosh|url=http://news.bbc.co.uk/1/hi/sci/tech/8621880.stm|publisher=BBC News|date=2010-04-15}}</ref><ref>{{cite news|publisher=Times Online|url=http://business.timesonline.co.uk/tol/business/law/article7098157.ece|title=Science writer Simon Singh wins bitter libel battle|author=Mark Henderson|location=London|date=2010-04-16}}</ref>

In recent decades chiropractic gained legitimacy and greater acceptance by medical physicians and [[health plan]]s, and enjoyed a strong political base and sustained demand for services. However, its future seemed uncertain: as the number of practitioners grew, [[evidence-based medicine]] insisted on treatments with demonstrated value, [[managed care]] restricted payment, and competition grew from [[massage therapist]]s and other health professions. The profession responded by marketing natural products and devices more aggressively, and by reaching deeper into [[alternative medicine]] and [[primary care]].<ref name=Cooper>{{cite pmid|12669653}}</ref>

==Effectiveness==
{{Split section|date=December 2012}}
Opinions differ as to the effectiveness of chiropractic treatments.

Many studies of treatments used by chiropractors have been conducted, often with conflicting results.<ref name=Ernst-eval/><ref name=Bronfort-Haas/> Manual therapies commonly used by chiropractors are as effective as other manual therapies for the treatment of low back pain,<ref name=Cochrane-2011/><ref name=Dagenais-2010/> and might also be effective for the treatment of lumbar disc herniation with radiculopathy,<ref name="Leininger B, Bronfort G, Evans R, Reiter T 2011 105–25">{{cite journal|journal= Phys Med Rehabil Clin N Am|year=2011|volume=22|issue=1|pages=105–25|title= Spinal manipulation or mobilization for radiculopathy: a systematic review|author= Leininger B, Bronfort G, Evans R, Reiter T|pmid=21292148|doi=10.1016/j.pmr.2010.11.002}}</ref><ref name="Hahne AJ, Ford JJ, McMeeken JM 2010 E488–504">{{cite journal|journal= Spine|year=2010|volume=35|issue=11|pages=E488–504|title= Conservative management of lumbar disc herniation with associated radiculopathy: a systematic review|author= Hahne AJ, Ford JJ, McMeeken JM|pmid=20421859|doi=10.1097/BRS.0b013e3181cc3f56}}</ref> neck pain,<ref name="Gross A, Miller J, D'Sylva J, Burnie SJ, Goldsmith CH, Graham N, Haines T, Brønfort G, Hoving JL 2010 315–333">{{cite journal|journal= Manual Therapy|year= 2010|volume=15|issue=4|pages=315–333|title= Manipulation or mobilisation for neck pain: a Cochrane Review|author= Gross A, Miller J, D'Sylva J, Burnie SJ, Goldsmith CH, Graham N, Haines T, Brønfort G, Hoving JL|pmid=20510644|doi= 10.1016/j.math.2010.04.002 }}</ref> some forms of headache,<ref name="Chaibi A, Tuchin PJ, Russell MB 2011">{{cite journal|journal= J Headache Pain|year=2011|volume= 12|issue= 2|pages= 127–33|title= Manual therapies for migraine: a systematic review|author= Chaibi A, Tuchin PJ, Russell MB|pmid=21298314|doi=10.1007/s10194-011-0296-6|pmc=3072494}}</ref><ref name="Bronfort G, Nilsson N, Haas M et al. 2004 CD001878">{{cite journal|journal= Cochrane Database Syst Rev|year=2004|issue=3|pages=CD001878|title= Non-invasive physical treatments for chronic/recurrent headache|author= Bronfort G, Nilsson N, Haas M ''et al.''|doi=10.1002/14651858.CD001878.pub2|pmid=15266458|editor1-last= Brønfort|editor1-first= Gert}}</ref> and some extremity joint conditions.<ref name="Brantingham JW, Globe G, Pollard H, Hicks M, Korporaal C, Hoskins W 2009 53–71">{{cite journal|author= Brantingham JW, Globe G, Pollard H, Hicks M, Korporaal C, Hoskins W|title= Manipulative therapy for lower extremity conditions: expansion of literature review|journal= J Manipulative Physiol Ther|volume=32|issue=1|pages=53–71|year=2009|pmid=19121464|doi=10.1016/j.jmpt.2008.09.013}}</ref><ref name="pmid21109059">{{Cite pmid|21109059}}</ref> While guidelines issued by the WHO state that chiropractic care may be considered safe when employed skillfully and appropriately,<ref name=WHO-guidelines/> chiropractic spinal manipulation is frequently associated with mild to moderate adverse effects, and with serious or fatal [[Complication (medicine)|complications]] in rare cases.<ref name=Ernst-adverse/><ref name=CCA-CFCREAB-CPG/><ref name=Ernst-death/> The efficacy and cost-effectiveness of maintenance chiropractic care are unproven.<ref name=Leboeuf-Yde-C/>

Many controlled clinical studies of [[spinal manipulation]] have been conducted, but their results often disagree<ref name=Ernst-Canter>{{cite journal|journal= J R Soc Med|year=2006|volume=99|issue=4|pages=192–6|title= A systematic review of systematic reviews of spinal manipulation|author= Ernst E, Canter PH|doi=10.1258/jrsm.99.4.192|pmid=16574972|url=http://www.jrsm.org/cgi/content/full/99/4/192|laysummary=http://news.bbc.co.uk/2/hi/health/4824594.stm|laysource= BBC News|laydate=2006-03-22|pmc= 1420782}}</ref> and they are typically of low methodological quality.<ref><ref{{cite journal|journal=[[Spine (journal)|Spine]]|year=2008|volume=33|issue=8|pages=914–8|title= The use of expertise-based randomized controlled trials to assess spinal manipulation and acupuncture for low back pain: a systematic review|author= Johnston BC, da Costa BR, Devereaux PJ, Akl EA, Busse JW; Expertise-Based RCT Working Group|doi=10.1097/BRS.0b013e31816b4be4|pmid=18404113}}</ref> A 2010 report found that manual therapies commonly used by chiropractors are effective for the treatment of low back pain, neck pain, some kinds of headaches and a number of extremity joint conditions.<ref name=Bronfort-Haas>{{cite journal|journal= Chiropractic & Osteopathy|year=2010|volume=18|issue=3|title= Effectiveness of manual therapies: the UK evidence report|author= Bronfort G, Haas M, Evans R, Leininger B, Triano J|doi=10.1186/1746-1340-18-3|pmid=20184717|url=http://chiromt.com/content/18/1/3|pmc=2841070|page= 3}}</ref>

A 2008 critical review found that with the possible exception of back pain, chiropractic manipulation has not been shown to be effective for any medical condition.<ref name=Ernst-eval>{{cite journal|journal= [[J Pain Symptom Manage]]|year=2008|volume=35|issue=5|pages=544–62|title= Chiropractic: a critical evaluation|author= Ernst E|doi=10.1016/j.jpainsymman.2007.07.004|pmid=18280103 }}</ref> Health claims made by chiropractors regarding use of manipulation for pediatric health conditions are supported by only low levels of scientific evidence<ref name=Kemper/><ref name=Gotlib>{{cite journal|journal= Chiropr Osteopat|year=2008|volume=16|page=11|title= Chiropractic manipulation in pediatric health conditions – an updated systematic review|author= Gotlib A, Rupert R|url=http://chiroandosteo.com/content/16/1/11|doi=10.1186/1746-1340-16-11|pmid=18789139|pmc= 2553791|issue=1}}</ref> that does not demonstrate clinically relevant benefits.<ref>{{cite journal|author=Ernst E|title=Chiropractic manipulation, with a deliberate 'double entendre'|journal=Arch Dis Child|volume=94|issue=6|page=411|year=2009|pmid=19460920|doi=10.1136/adc.2009.158170 }}</ref>

Most research has focused on [[spinal manipulation]] in general,<ref name=ResponseToMeeker>{{cite journal|journal= Ann Intern Med|year=2002|volume=137|issue=8|page=702|title= Chiropractic: in response|author= Meeker WC, Haldeman S|url=http://annals.org/cgi/reprint/137/8/701.pdf|format=PDF }}</ref> rather than solely on chiropractic manipulation.<ref name=Villanueva-Russell/> A 2002 review of [[randomized clinical trial]]s of spinal manipulation<ref name=Meeker-Haldeman>{{cite journal|journal=[[Ann Intern Med]]|year=2002|volume=136|issue=3|pages=216–27|title=Chiropractic: a profession at the crossroads of mainstream and alternative medicine|author=Meeker WC, Haldeman S|pmid=11827498|url=http://www.annals.org/cgi/reprint/136/3/216.pdf|format=PDF }}</ref> was criticized for not making this distinction;<ref>{{cite journal|author= Ernst E|title= Chiropractic|journal= Ann Intern Med|volume=137|issue=8|page=701|year=2002|pmid=12379081|url=http://annals.org/cgi/reprint/137/8/701.pdf|format=PDF }}</ref> however, the review's authors stated that they did not consider this difference to be a significant point as research on spinal manipulation is equally useful regardless of which practitioner provides it.<ref name=ResponseToMeeker/>

There is a wide range of ways to measure treatment outcomes.<ref>{{cite journal|journal=J Manipulative Physiol Ther|year=2008|volume=31|issue=5|pages=355–75|title=Measures in chiropractic research: choosing patient-based outcome assessments|author=Khorsan R, Coulter ID, Hawk C, Choate CG|doi=10.1016/j.jmpt.2008.04.007|pmid=18558278 }}</ref> Chiropractic care, like all medical treatment, benefits from the [[placebo response]].<ref>{{cite journal|journal=Ann Intern Med|year=2002|volume=136|issue=11|pages=817–25|title=The placebo effect in alternative medicine: can the performance of a healing ritual have clinical significance?|author=Kaptchuk TJ|pmid=12044130|url=http://annals.org/cgi/reprint/136/11/817.pdf|format=PDF }}</ref> It is difficult to construct a trustworthy placebo for clinical trials of [[spinal manipulative therapy]] (SMT), as experts often disagree about whether a proposed placebo actually has no effect.<ref>{{cite journal|journal=[[Aust J Physiother]]|year=2006|volume=52|issue=2|pages=135–8|title=Selecting an appropriate placebo for a trial of spinal manipulative therapy|author=Hancock MJ, Maher CG, Latimer J, McAuley JH|pmid=16764551|url=http://ajp.physiotherapy.asn.au/AJP/vol_52/2/AustJPhysiotherv52i2Hancock.pdf|format=PDF|doi=10.1016/S0004-9514(06)70049-6 }}</ref> The efficacy of maintenance care in chiropractic is unknown.<ref name=Leboeuf-Yde-C>{{cite journal|journal=Chiropr Osteopat|year=2008|volume=16|page=3|title=Maintenance care in chiropractic – what do we know?|author=Leboeuf-Yde C, Hestbæk L|doi=10.1186/1746-1340-16-3|pmid=18466623|url=http://chiroandosteo.com/content/16/1/3|pmc=2396648|issue=1}}</ref>

Available evidence covers the following conditions:

* '''[[Low back pain]]'''. Specific guidelines concerning the treatment of nonspecific (i.e., unknown cause) low back pain remain inconsistent between countries.<ref name=Murphy>{{cite journal|journal= J Manipulative Physiol Ther|year=2006|volume=29|issue=7|pages=576–81, 581.e1–2|title= Inconsistent grading of evidence across countries: a review of low back pain guidelines|author= Murphy AYMT, van Teijlingen ER, Gobbi MO|doi=10.1016/j.jmpt.2006.07.005|pmid=16949948|url=http://jmptonline.org/article/S0161-4754(06)00186-2/fulltext}}</ref> A 2011 [[Cochrane review]] found strong evidence that there is no clinically meaningful difference between spinal manipulation and other treatments for reducing pain and improving function for chronic low back pain.<ref name=Cochrane-2011>{{cite journal|journal= [[Cochrane Database Syst Rev]]|year=2011|issue=2|pages=CD008112|title= Spinal manipulative therapy for chronic low-back pain|author= Rubinstein SM, van Middelkoop M, Assendelft WJ, de Boer MR, van Tulder MW|doi=10.1002/14651858.CD008112.pub2|pmid=21328304|volume=|editor1-last= Rubinstein|editor1-first= Sidney M}}</ref> A 2010 Cochrane review found no current evidence to support or refute a clinically significant difference between the effects of combined chiropractic interventions and other interventions for chronic or mixed duration low back pain.<ref>{{cite journal|journal= Cochrane Database Syst Rev|year=2010|issue=4|pages=CD005427|title= Combined chiropractic interventions for low-back pain|author= Walker BF, French SD, Grant W, Green S|doi= 10.1002/14651858.CD005427.pub2|pmid=20393942|volume= 4|editor1-last= Walker|editor1-first= Bruce F}}</ref> A 2010 systematic review found that most studies suggest spinal manipulation achieves equivalent or superior improvement in pain and function when compared with other commonly used interventions for short, intermediate, and long-term follow-up.<ref name=Dagenais-2010>{{cite journal|journal= [[Spine J]]|year=2010|volume=10|issue=10|pages=918–940|title= NASS Contemporary Concepts in Spine Care: Spinal manipulation therapy for acute low back pain|author= Dagenais S, Gay RE, Tricco AC, Freeman MD, Mayer JM|doi=10.1016/j.spinee.2010.07.389|pmid=20869008}}</ref> A 2008 review found strong evidence that SM is similar in effect to medical care with exercise.<ref name=Bronfort-2008>{{cite journal|journal= [[Spine J]]|year=2008|volume=8|issue=1|pages=213–25|title= Evidence-informed management of chronic low back pain with spinal manipulation and mobilization|author= Bronfort G, Haas M, Evans R, Kawchuk G, Dagenais S|doi=10.1016/j.spinee.2007.10.023|pmid=18164469}}</ref> A 2008 literature synthesis found good evidence supporting SM for low back pain regardless of duration.<ref name=Lawrence-2008>{{cite journal|title= Chiropractic management of low back pain and low back-related leg complaints: a literature synthesis|author= Lawrence DJ, Meeker W, Branson R ''et al.''|journal= J Manipulative Physiol Ther|volume=31|issue=9|pages=659–74|year=2008|pmid=19028250|doi=10.1016/j.jmpt.2008.10.007}} An earlier, freely readable version is in: {{cite web|title= Chiropractic management of low back pain and low back related leg complaints|author= Meeker W, Branson R, Bronfort G ''et al.''|url=http://ccgpp.org/lowbackliterature.pdf|format=PDF|year=2007|accessdate=2008-11-28|publisher= [[Council on Chiropractic Guidelines and Practice Parameters]]}}</ref> A 2007 review found good evidence that SM is moderately effective for low back pain lasting more than 4 weeks.<ref>{{cite journal|journal= Ann Intern Med|year=2007|volume=147|issue=7|pages=492–504|title= Nonpharmacologic therapies for acute and chronic low back pain: a review of the evidence for an[American Pain Society/American College of Physicians clinical practice guideline|author= Chou R, Huffman LH; American Pain Society; American College of Physicians|pmid=17909210|url=http://annals.org/cgi/content/full/147/7/492|doi=10.1001/archinte.147.3.492}}</ref> In 2007 the American College of Physicians and the [[American Pain Society]] recommended that clinicians consider the addition of spinal manipulation for patients who do not improve with self care options.<ref>{{cite journal|journal= Ann Intern Med|date= October 2, 2007|volume=147|issue=7|pages=478–91|title= Diagnosis and treatment of low back pain: a joint clinical practice guideline from the American College of Physicians and the American Pain Society|author= Chou R, Qaseem A, Snow V ''et al.''|pmid=17909209|url=http://annals.org/cgi/content/full/147/7/478|doi=10.7326/0003-4819-147-7-200710020-00006}}</ref> Methods for formulating treatment guidelines for low back pain differ significantly between countries, casting some doubt on their reliability.<ref name=Murphy/>

* '''[[Radiculopathy]]'''. There is no overall consensus on the effectiveness of manual therapies for radiculopathies. There is moderate quality evidence to support the use of spinal manipulation for the treatment of acute [[Sciatica|lumbar radiculopathy]]<ref name="Leininger B, Bronfort G, Evans R, Reiter T 2011 105–25"/> and acute lumbar [[disc herniation]] with associated radiculopathy.<ref name="Hahne AJ, Ford JJ, McMeeken JM 2010 E488–504"/> The evidence for chronic lumbar spine-related extremity symptoms and cervical spine-related extremity symptoms of any duration is low or very low and no evidence exists for the treatment of thoracic radiculopathy.<ref name="Leininger B, Bronfort G, Evans R, Reiter T 2011 105–25"/>

* '''[[Whiplash (medicine)|Whiplash]] and other [[neck pain]]'''. There is no overall consensus on the effectiveness of manual therapies for [[neck pain]].<ref name=Vernon>{{cite journal|journal= [[Eura Medicophys]]|year=2007|volume=43|issue=1|pages=91–118|title= Manual therapy for neck pain: an overview of randomized clinical trials and systematic reviews|author= Vernon H, Humphreys BK|pmid=17369783|url=http://www.minervamedica.it/en/getfreepdf.php?cod=R33Y2007N01A0091|format=PDF}}</ref> A 2011 systematic review concluded that thoracic spine manipulation may provide short-term improvement in patients with acute or subacute mechanical neck pain; although the body of literature is still weak.<ref name=Cross>{{cite journal|journal=J Orthop Sports Phys Ther|year=2011|volume=41|issue=9|pages=633–642|title=Thoracic spine thrust manipulation improves pain, range of motion, and self-reported function in patients with mechanical neck pain: a systematic review|author= Cross KM, Kuenze C, Grindstaff TL, Hertel J.|pmid=21885904|doi=10.2519/jospt.2011.3670}}</ref> A 2010 Cochrane review found low evidence that manipulation was more effective than a control for neck pain, and moderate evidence that cervical manipulation and mobilisation produced similar effects on pain, function and patient satisfaction.<ref name="Gross A, Miller J, D'Sylva J, Burnie SJ, Goldsmith CH, Graham N, Haines T, Brønfort G, Hoving JL 2010 315–333"/> A 2010 systematic review found low level evidence that suggests chiropractic care improves cervical range of motion and pain in the management of whiplash.<ref>{{cite journal|journal= Work (A Journal of Prevention, Assessment and Rehabilitation)|year= 2010|volume=35|issue=3|pages=369–394|title= A systematic review of chiropractic management of adults with Whiplash Associated Disorders: recommendations for advancing evidence based practice and research|author= Shaw L, Descarreaux M, Bryans R, Duranleau M, Marcoux H, Potter B, Ruegg R, Watkin R, White E|pmid=20364057|doi= 10.3233/WOR-2010-0996 }}</ref> A 2009 systematic review of controlled clinical trials found no evidence that chiropractic spinal manipulation is effective for whiplash injury.<ref>{{cite journal|journal=Focus Altern Complement Ther|year=2009|volume=14|pages=85–6|title=Chiropractic spinal manipulation for whiplash injury? A systematic review of controlled clinical trials|author=Ernst E|url=http://www.medicinescomplete.com/journals/fact/current/fact1402a05t01.htm }}</ref> A 2008 review found evidence that suggests that manual therapy and exercise are more effective than alternative strategies for patients with neck pain.<ref name=Hurwitz-2008/> A 2007 review found that spinal manipulation and mobilization are effective for neck pain.<ref name=Vernon/> A 2005 review found evidence supporting spinal mobilization, and limited evidence supporting spinal manipulation for whiplash.<ref>{{cite journal|journal= [[Pain Res Manag]]|year=2005|volume=10|issue=1|pages=21–32|title= Treatment of whiplash-associated disorders—part I: non-invasive interventions|author= Conlin A, Bhogal S, Sequeira K, Teasell R|pmid=15782244}}</ref>

* '''[[Headache]]'''. There is no overall consensus on the effectiveness of manual therapies for headaches. Of two systematic reviews published in 2011, one found evidence that spinal manipulation might be as effective as [[propranolol]] or [[topiramate]] in the prevention of [[migraine headache]]s,<ref name="Chaibi A, Tuchin PJ, Russell MB 2011"/> the other concluded that evidence does not support the use of spinal manipulation for the treatment of migraine headaches.<ref>{{cite journal|journal= Cephalalgia|year=2011|volume=31|issue=8|pages=964–970|title=Spinal manipulations for the treatment of migraine: A systematic review of randomized clinical trials|author= Posadzki P, Ernst E|pmid=21511952|doi=10.1177/0333102411405226 }}</ref> A 2004 Cochrane review found evidence that suggests spinal manipulation may be effective for migraine, tension headache and cervicogenic headache.<ref name="Bronfort G, Nilsson N, Haas M et al. 2004 CD001878"/> A 2006 review found inconclusive evidence supporting manual therapies for [[tension headache]].<ref>{{cite journal|journal= [[Clin J Pain]]|year=2006|volume=22|issue=3|pages=278–85|title= Are manual therapies effective in reducing pain from tension-type headache?: a systematic review|author= Fernández-de-las-Peñas C, Alonso-Blanco C, Cuadrado ML, Miangolarra JC, Barriga FJ, Pareja JA|doi=10.1097/01.ajp.0000173017.64741.86|pmid=16514329}}</ref> A 2005 review found that spinal manipulation showed a trend toward benefit in the treatment of tension headache, but the evidence was weak.<ref>{{cite journal|journal=[[Headache (journal)|Headache]]|year=2005|volume=45|issue=6|pages=738–46|title= Physical treatments for headache: a structured review|doi=10.1111/j.1526-4610.2005.05141.x|author= Biondi DM|pmid=15953306}}</ref>

* '''Extremity conditions'''. A 2011 systematic review and meta-analysis concluded that the addition of manual mobilizations to an exercise program for the treatment of knee osteoarthritis resulted in better pain relief then a supervised exercise program alone and suggested that manual therapists consider adding manual mobilisation to optimise supervised active exercise programs.<ref>{{cite journal|author= Jansen MJ, Viechtbauer W, Lenssen AF, Hendriks EJ, de Bie RA|title= Strength training alone, exercise therapy alone, and exercise therapy with passive manual mobilisation each reduce pain and disability in people with knee osteoarthritis: a systematic review|journal= J Physiother|volume=57|issue=1|pages=11–20|year=2011|pmid=21402325|doi=10.1016/S1836-9553(11)70002-9}}</ref> There is silver level evidence that manual therapy is more effective than exercise for the treatment of hip osteoarthritis, however this evidence could be considered to be inconclusive.<ref>{{cite journal|journal= Man Ther|year=2011|volume=16|issue=2|pages=109–117|title= Manual therapy for osteoarthritis of the hip or knee - a systematic review|author= French HP, Brennan A, White B, Cusack T|doi= 10.1016/j.math.2010.10.011|pmid=21146444}}</ref> A 2008 systematic review found that the addition of cervical spine mobilization to a treatment regimen for lateral epicondylosis ([[tennis elbow]]) resulted in significantly better pain relief and functional improvements in both the short and long-term.<ref>{{cite journal|journal= Journal of Manual & Manipulative Therapy|year=2008|volume=16|issue=4|pages=225–37|title= A Systematic Review of the Effectiveness of Manipulative Therapy in Treating Lateral Epicondylalgia|author= Herd CR, Meserve BB.|doi= 10.1179/106698108790818288|pmid=19771195|pmc= 2716156}}</ref> There is a small amount of research into the efficacy of chiropractic treatment for [[upper limb]]s,<ref>{{cite journal|journal= J Manipulative Physiol Ther|year=2008|volume=31|issue=2|pages=146–59|title= Chiropractic treatment of upper extremity conditions: a systematic review|author= McHardy A, Hoskins W, Pollard H, Onley R, Windsham R|doi=10.1016/j.jmpt.2007.12.004|pmid=18328941}}</ref> limited to low level evidence supporting chiropractic management of [[shoulder pain]]<ref name="pmid21109059"/> and limited or fair evidence supporting chiropractic management of [[human leg|leg]] conditions.<ref name="Brantingham JW, Globe G, Pollard H, Hicks M, Korporaal C, Hoskins W 2009 53–71"/>

* '''Other'''. A 2012 systematic review found insufficient low bias evidence to support the use of spinal manipulation as a therapy for the treatment of hypertension.<ref>{{cite journal|journal=J Manipulative Physiol Ther|year=2012|volume=35|issue=3 |pages=235–43|title=Spinal manipulation for the treatment of hypertension: a systematic qualitative literature review|author=Mangum K, Partna L, Vavrek D|url=|doi= 10.1016/j.jmpt.2012.01.005|pmid=22341795|pmc= }}</ref> A systematic review in 2011 found moderate evidence to support the use of manual therapy for cervicogenic dizziness.<ref>{{cite journal|journal=Chiropractic and Manual Therapies|year=2011|volume=19|issue= 1|page=21|title= Manual therapy with and without vestibular rehabilitation for cervicogenic dizziness: a systematic review|author= Lystad RP, Bell G, Bonnevie-Svendsen M, Carter CV|url=http://chiromt.com/content/19/1/21/abstract|doi=10.1186/2045-709X-19-21|pmid=21923933|pmc=3182131 }}</ref> There is very weak evidence for chiropractic care for adult [[scoliosis]] (curved or rotated spine)<ref>{{cite journal|journal=Spine|year=2007|volume=32|issue= 19 Suppl|pages=S130–4|title= A systematic literature review of nonsurgical treatment in adult scoliosis|author= Everett CR, Patel RK|doi=10.1097/BRS.0b013e318134ea88|pmid=17728680}}</ref> and no scientific data for [[idiopathic]] adolescent scoliosis.<ref>{{cite journal|journal=[[Scoliosis (journal)|Scoliosis]]|year=2008|volume=3|page=2|title= Manual therapy as a conservative treatment for adolescent idiopathic scoliosis: a systematic review|author= Romano M, Negrini S|doi=10.1186/1748-7161-3-2|pmid=18211702|url=http://scoliosisjournal.com/content/3/1/2|pmc=2262872|issue=1}}</ref> A 2007 systematic review found that few studies of chiropractic care for nonmusculoskeletal conditions are available, and they are typically not of high quality; it also found that the entire clinical encounter of chiropractic care (as opposed to just SM) provides benefit to patients with cervicogenic dizziness, and that the evidence from reviews is negative, or too weak to draw conclusions, for a wide variety of other nonmusculoskeletal conditions, including [[ADHD]]/[[learning disabilities]], [[dizziness]], [[high blood pressure]], and [[Visual perception|vision]] conditions.<ref>{{cite journal|journal= J Altern Complement Med|year=2007|volume=13|issue=5|pages=491–512|title= Chiropractic care for nonmusculoskeletal conditions: a systematic review with implications for whole systems research|author= Hawk C, Khorsan R, Lisi AJ, Ferrance RJ, Evans MW|doi=10.1089/acm.2007.7088|pmid=17604553}}</ref> Other reviews have found no evidence of significant benefit for [[asthma]],<ref>Asthma:
*{{cite journal|author=Ernst E|title=Spinal manipulation for asthma: a systematic review of randomised clinical trials|journal=Respir Med|volume=103|issue=12|pages=1791–5|year=2009|pmid=19646855|doi=10.1016/j.rmed.2009.06.017 }}
*{{cite journal|author=Hondras MA, Linde K, Jones AP|title=Manual therapy for asthma|journal=Cochrane Database Syst Rev|issue=2|pages=CD001002|year=2005|pmid=15846609|doi=10.1002/14651858.CD001002.pub2|editor1-last=Hondras|editor1-first=Maria A }}
*{{cite journal|author=Kaminskyj A, Frazier M, Johnstone K, Gleberzon BJ|title=Chiropractic care for patients with asthma: A systematic review of the literature|journal=J Can Chiropr Assoc|volume=54|issue=1|pages=24–32|year=2010|pmid=20195423|pmc=2829683|doi=|url=http://www.jcca-online.org/ecms.ashx/PDF/2010/2010-1/jcca-v54-1-024indd.pdf|format=PDF }}
</ref> [[baby colic]],<ref name=Gotlib/><ref>Baby colic:
*{{cite journal|author=Ernst E|title=Chiropractic spinal manipulation for infant colic: a systematic review of randomised clinical trials|journal=Int J Clin Pract|volume=63|issue=9|pages=1351–3|year=2009|pmid=19691620|doi=10.1111/j.1742-1241.2009.02133.x }}
*{{cite book|author=Husereau D, Clifford T, Aker P, Leduc D, Mensinkai S|title=Spinal Manipulation for Infantile Colic|isbn=1-894978-11-0|url=http://cadth.ca/media/pdf/177_spinal_manipulation_tr_e.pdf|format=PDF|accessdate=2008-10-06|location=Ottawa|publisher=Canadian Coordinating Office for Health Technology Assessment|year=2003|series=Technology report no. 42 }}
</ref> [[bedwetting]],<ref>{{cite journal|journal=Cochrane Database Syst Rev|year=2005|issue=2|pages=CD005230|title=Complementary and miscellaneous interventions for nocturnal enuresis in children|author=Glazener CM, Evans JH, Cheuk DK|doi=10.1002/14651858.CD005230|pmid=15846744|editor1-last=Glazener|editor1-first=Cathryn MA }}</ref> [[carpal tunnel syndrome]],<ref>{{cite journal|author=O'Connor D, Marshall S, Massy-Westropp N|title=Non-surgical treatment (other than steroid injection) for carpal tunnel syndrome|journal=Cochrane Database Syst Rev|issue=1|pages=CD003219|year=2003|pmid=12535461|doi=10.1002/14651858.CD003219|editor1-last=O'Connor|editor1-first=Denise }}</ref> [[fibromyalgia]],<ref>Fibromyalgia:
*{{cite journal|journal= [[Curr Pharm Des]]|year=2006|volume=12|issue=1|pages=47–57|title= Complementary and alternative medical therapies in fibromyalgia|author= Sarac AJ, Gur A|pmid=16454724|doi= 10.2174/138161206775193262}}
*{{cite journal|author= Schneider M, Vernon H, Ko G, Lawson G, Perera J|title= Chiropractic management of fibromyalgia syndrome: a systematic review of the literature|journal= J Manipulative Physiol Ther|volume=32|issue=1|pages=25–40|year=2009|pmid=19121462|doi=10.1016/j.jmpt.2008.08.012 }}
*{{cite journal|author=Ernst E|title=Chiropractic treatment for fibromyalgia: a systematic review|journal=Clin Rheumatol|volume= 28|issue= 10|pages= 1175–8|year=2009|pmid=19544042|doi=10.1007/s10067-009-1217-9 }}
</ref> [[gastrointestinal disorders]],<ref>{{cite journal|journal= Can J Gastroenterol|year=2011|volume=25|issue=1|pages=39–49|title= Chiropractic treatment for gastrointestinal problems: A systematic review of clinical trials|author= Ernst E|pmid=21258667|pmc= 3027333}}</ref> kinetic imbalance due to [[Suboccipital muscles|suboccipital]] strain (KISS) in infants,<ref name=Gotlib/><ref>{{cite journal|author= Brand PL, Engelbert RH, Helders PJ, Offringa M|title= [Systematic review of the effects of therapy in infants with the KISS-syndrome (kinetic imbalance due to suboccipital strain)]|language=Dutch|journal= Ned Tijdschr Geneeskd|volume=149|issue=13|pages=703–7|year=2005|pmid=15819137}}</ref> [[menstrual cramps]],<ref>{{cite journal|journal= Cochrane Database Syst Rev|year=2006|issue=3|pages=CD002119|title= Spinal manipulation for primary and secondary dysmenorrhoea|author= Proctor ML, Hing W, Johnson TC, Murphy PA|doi=10.1002/14651858.CD002119.pub3|pmid=16855988|volume= 3|editor1-last= Proctor|editor1-first= Michelle }}</ref> or [[pelvic girdle pain|pelvic and back pain during pregnancy]].<ref>{{cite journal|author= Pennick VE, Young G|title= Interventions for preventing and treating pelvic and back pain in pregnancy|journal= Cochrane Database Syst Rev|issue=2|pages=CD001139|year=2007|pmid=17443503|doi=10.1002/14651858.CD001139.pub2|editor1-last= Pennick|editor1-first= Victoria}}</ref>


===Safety===
===Safety===
The safe application of spinal manipulation requires a thorough medical history, assessment, diagnosis and plan of management. Manipulative therapists, including chiropractors, must rule out [[contraindications]] to HVLA spinal manipulative techniques. Absolute contraindications refers to diagnoses and conditions that put the patient at risk to developing [[adverse events]]. For example, a diagnosis of [[rheumatoid arthritis]] and other conditions that structurally destabilizes joints, is an absolute contraindication of SMT to the upper cervical spine. Relative contraindications, such as [[osteoporosis]] are conditions where increased risk is acceptable in some situations and where mobilization and [[soft-tissue]] techniques would be treatments of choice. Most contraindication apply only to the manipulation of the affected region.<ref name=CCA-CFCREAB-CPG>{{cite journal|journal=J Can Chiropr Assoc|year=2005|volume=49|issue=3|pages=158–209|title= Chiropractic clinical practice guideline: evidence-based treatment of adult neck pain not due to whiplash|author= Anderson-Peacock E, Blouin JS, Bryans R ''et al.''|url=http://jcca-online.org/ecms.ashx/PDF/2005/2005-3/Chiropracticclinicalpracticeguideline-evidence-basedtreatmentofadultneckpainnotduetowhiplash.pdf|format=PDF|pmid=17549134|pmc=1839918 }}<br/>• {{cite journal|journal=J Can Chiropr Assoc|year=2008|volume=52|issue=1|pages=7–8|title=A Clinical Practice Guideline Update from The CCA•CFCREAB-CPG|author= Anderson-Peacock E, Bryans B, Descarreaux M ''et al.''|url=http://jcca-online.org/ecms.ashx/PDF/2008/2008-1/ClinicalPracticeGuidelineUpdatefromTheCCACFCREABCPG.pdf|format=PDF|pmid=18327295|pmc=2258235 }}</ref>
Chiropractic care in general is safe when employed skillfully and appropriately.<!--<ref name=WHO-guidelines/> --> Manipulation is regarded as relatively safe, but as with all therapeutic interventions, complications can arise, and it has known adverse effects, risks and contraindications.<!--<ref name=WHO-guidelines/> --> Absolute [[contraindication]]s to spinal manipulative therapy are conditions that should not be manipulated; these contraindications include [[rheumatoid arthritis]] and conditions known to result in unstable joints.<ref name=WHO-guidelines/>


Adverse events in spinal manipulation studies are believed to be under-reported <ref name=Ernst-2012>{{cite journal|journal=N Z Med J|year=2012|volume=125|issue=1353|pages=87–140|title= Reporting of adverse effects in randomised clinical trials of chiropractic manipulations: a systematic review|author= Ernst E, Posadzki P|pmid=22522273|url=|pmc=}}</ref> and appear to be more common following HVLA manipulation than mobilization.<ref name="Hurwitz EL, Morgenstern H, Vassilaki M, Chiang LM 2005 1477–84">{{cite journal|author=Hurwitz EL, Morgenstern H, Vassilaki M, Chiang LM|title=Frequency and clinical predictors of adverse reactions to chiropractic care in the UCLA neck pain study|journal=[[Spine (journal)|Spine]]|volume=30|issue=13|pages=1477–84|year=2005|month=July|pmid=15990659|doi= 10.1097/01.brs.0000167821.39373.c1|url=}}</ref>
Sustained chiropractic care is promoted as a preventative tool, but unnecessary manipulation could present a risk to patients. Some chiropractors are concerned by the routine unjustified claims chiropractors have made.<ref name=Ernst-eval/>
Mild, frequent and temporary adverse events occur in SMT which include temporary increase in pain, tenderness and stiffness.<ref name=Ernst-adverse/> These events typically dissipates within 24–48 hours <ref name=Gouveia>{{cite journal|author= Gouveia LO, Castanho P, Ferreira JJ|title= Safety of chiropractic interventions: a systematic review|journal=Spine|volume=34|issue=11|pages=E405–13|year=2009|pmid=19444054|doi=10.1097/BRS.0b013e3181a16d63}}</ref> Serious injuries and fatal consequences , especially to SM in the upper cervical region, can occur.<ref>{{cite journal|journal=Spine|year=2007|volume=32|issue=21|pages=2375–8|title= Safety of chiropractic manipulation of the cervical spine: a prospective national survey|author= Thiel HW, Bolton JE, Docherty S, Portlock JC|doi=10.1097/BRS.0b013e3181557bb1|pmid=17906581}}</ref> but are regarded as rare when spinal manipulation is employed skillfully and appropriately.<ref name=CCA-CFCREAB-CPG>{{cite journal|journal=J Can Chiropr Assoc|year=2005|volume=49|issue=3|pages=158–209|title= Chiropractic clinical practice guideline: evidence-based treatment of adult neck pain not due to whiplash|author= Anderson-Peacock E, Blouin JS, Bryans R ''et al.''|url=http://jcca-online.org/ecms.ashx/PDF/2005/2005-3/Chiropracticclinicalpracticeguideline-evidence-basedtreatmentofadultneckpainnotduetowhiplash.pdf|format=PDF|pmid=17549134|pmc=1839918 }}<br/>• {{cite journal|journal=J Can Chiropr Assoc|year=2008|volume=52|issue=1|pages=7–8|title=A Clinical Practice Guideline Update from The CCA•CFCREAB-CPG|author= Anderson-Peacock E, Bryans B, Descarreaux M ''et al.''|url=http://jcca-online.org/ecms.ashx/PDF/2008/2008-1/ClinicalPracticeGuidelineUpdatefromTheCCACFCREABCPG.pdf|format=PDF|pmid=18327295|pmc=2258235 }}</ref>


There is considerable debate regarding the relationship of spinal manipulation to the upper cervical spine and [[stroke]]. Stroke is [[Association (statistics)|statistically associated]] with both general practitioner and chiropractic services in persons under 45 years of age suggesting that these associations are likely explained by preexisting conditions.<ref name=Hurwitz-2008>{{cite journal|journal=Spine|year=2008|volume=33|issue= 4 Suppl|pages=S123–52|title= Treatment of neck pain: noninvasive interventions: results of the Bone and Joint Decade 2000–2010 Task Force on Neck Pain and Its Associated Disorders|author= Hurwitz EL, Carragee EJ, van der Velde G ''et al.''|doi=10.1097/BRS.0b013e3181644b1d|pmid=18204386}}</ref><ref>{{cite journal|author= Paciaroni M, Bogousslavsky J|title= Cerebrovascular complications of neck manipulation|journal= Eur Neurol|volume=61|issue=2|pages=112–8|year=2009|pmid=19065058|doi=10.1159/000180314|url=http://content.karger.com/ProdukteDB/produkte.asp?Aktion=ShowFulltext&ArtikelNr=180314&ProduktNr=223840}}</ref><ref>{{cite journal|last=Cassidy|first=JD|coauthors=Boyle, E; Côté, P; He, Y; Hogg-Johnson, S; Silver, FL; Bondy, SJ|title=Risk of vertebrobasilar stroke and chiropractic care: results of a population-based case-control and case-crossover study.|journal=Spine|date=15|year=2008|month=Feb|volume=33|issue=4 Suppl|pages=S176-83|pmid=18204390|accessdate=2 December 2012}}</ref> Weak to moderately strong evidence supports causation (as opposed to statistical association) between [[cervical manipulation|cervical manipulative therapy]] and vertebrobasilar artery stroke.<ref>{{cite journal|journal=[[The Neurologist|Neurologist]]|year=2008|volume=14|issue=1|pages=66–73|title= Does cervical manipulative therapy cause vertebral artery dissection and stroke?|author= Miley ML, Wellik KE, Wingerchuk DM, Demaerschalk BM|doi=10.1097/NRL.0b013e318164e53d|pmid=18195663}}</ref> A 2012 systematic review determined that there is insufficient evidence to support a strong association or no association between cervical manipulation and stroke.<ref name=Haynes>{{cite journal|journal=International Journal of Clinical Practice|year=2012|volume=66|issue=10|pages=940–947|title= Assessing the risk of stroke from neck manipulation: a systematic review|author= Haynes MJ, Vincent K, Fischhoff C, Bremner AP, Lanlo O, Hankey GJ.|doi=10.1111/j.1742-1241.2012.03004.x|pmid=22994328|url=http://onlinelibrary.wiley.com/doi/10.1111/j.1742-1241.2012.03004.x/full}}</ref>
Relative contraindications are conditions where increased risk is acceptable in some situations and where low-force and soft-tissue techniques are treatments of choice; these contraindications include [[osteoporosis]].<ref name=WHO-guidelines/> Although most contraindications apply only to manipulation of the affected region, some neurological signs indicate referral to [[emergency medical services]]; these include sudden and severe [[headache]] or [[neck pain]] unlike that previously experienced.<ref name=CCA-CFCREAB-CPG>{{cite journal|journal=J Can Chiropr Assoc|year=2005|volume=49|issue=3|pages=158–209|title= Chiropractic clinical practice guideline: evidence-based treatment of adult neck pain not due to whiplash|author= Anderson-Peacock E, Blouin JS, Bryans R ''et al.''|url=http://jcca-online.org/ecms.ashx/PDF/2005/2005-3/Chiropracticclinicalpracticeguideline-evidence-basedtreatmentofadultneckpainnotduetowhiplash.pdf|format=PDF|pmid=17549134|pmc=1839918 }}<br/>• {{cite journal|journal=J Can Chiropr Assoc|year=2008|volume=52|issue=1|pages=7–8|title=A Clinical Practice Guideline Update from The CCA•CFCREAB-CPG|author= Anderson-Peacock E, Bryans B, Descarreaux M ''et al.''|url=http://jcca-online.org/ecms.ashx/PDF/2008/2008-1/ClinicalPracticeGuidelineUpdatefromTheCCACFCREABCPG.pdf|format=PDF|pmid=18327295|pmc=2258235 }}</ref>


===Cost-effectiveness===
Spinal manipulation is associated with frequent, mild and temporary [[Adverse effect (medicine)|adverse effects]],<ref name=Ernst-adverse/><ref name=CCA-CFCREAB-CPG/> including new or worsening pain or stiffness in the affected region.<ref>{{cite journal|journal=Spine|year=2007|volume=32|issue=21|pages=2375–8|title= Safety of chiropractic manipulation of the cervical spine: a prospective national survey|author= Thiel HW, Bolton JE, Docherty S, Portlock JC|doi=10.1097/BRS.0b013e3181557bb1|pmid=17906581}}</ref> They have been estimated to occur in 33% to 61% of patients, and frequently occur within an hour of treatment and disappear within 24 to 48 hours;<ref name=Gouveia>{{cite journal|author= Gouveia LO, Castanho P, Ferreira JJ|title= Safety of chiropractic interventions: a systematic review|journal=Spine|volume=34|issue=11|pages=E405–13|year=2009|pmid=19444054|doi=10.1097/BRS.0b013e3181a16d63}}</ref> adverse reactions appear to be more common following manipulation than mobilization.<ref>{{cite journal|author=Hurwitz EL, Morgenstern H, Vassilaki M, Chiang LM|title=Frequency and clinical predictors of adverse reactions to chiropractic care in the UCLA neck pain study|journal=[[Spine (journal)|Spine]]|volume=30|issue=13|pages=1477–84|year=2005|month=July|pmid=15990659|doi= 10.1097/01.brs.0000167821.39373.c1|url=}}</ref> Chiropractors are more commonly associated with serious manipulation related adverse effects than other professionals.<ref name=Ernst-death/>
Spinal manipulation is generally regarded as cost-effective treatment of musculoskeletal conditions when used alone or in combination with other treatment approaches.<ref>{{cite journal|journal= J Electromyogr Kinesiol|year=2012|volume=|issue=|pages=|title=Spinal manipulation epidemiology: Systematic review of cost effectiveness studies|author= Michaleff ZA, Lin CW, Maher CG, van Tulder MW|doi= 10.1016/j.jelekin.2012.02.011|pmid=22429823|pmc= }}</ref> Evidence supports the cost-effectiveness of using spinal manipulation for the treatment of sub-acute or chronic low back pain whereas the results for acute low back pain were inconsistent.<ref>{{cite journal|journal= European Spine Journal|year=2011|volume=20|issue=7|pages=1024–1038|title=Cost-effectiveness of guideline-endorsed treatments for low back pain: a systematic review|author= Lin CW, Haas M, Maher CG, Machado LA, van Tulder MW|doi=10.1007/s00586-010-1676-3|pmid=21229367|pmc= 3176706 }}</ref>


==Training==
Rarely,<ref name=WHO-guidelines/> spinal manipulation, particularly on the upper spine, can also result in complications that can lead to permanent disability or [[death]]; these can occur in adults<ref name=Ernst-adverse>{{cite journal|journal= [[J R Soc Med]]|year=2007|volume=100|issue=7|pages=330–8|title= Adverse effects of spinal manipulation: a systematic review|author= Ernst E|pmid=17606755|url=http://www.jrsm.org/cgi/content/full/100/7/330|doi=10.1258/jrsm.100.7.330|laysummary=http://www.medicalnewstoday.com/articles/75754.php|laysource= Med News Today|laydate=2007-07-02|pmc= 1905885}}</ref> and children.<ref name=Vohra>{{cite journal|journal=[[Pediatrics (journal)|Pediatrics]]|year=2007|volume=119|issue=1|pages=e275–83|title= Adverse events associated with pediatric spinal manipulation: a systematic review|author= Vohra S, Johnston BC, Cramer K, Humphreys K|doi=10.1542/peds.2006-1392|pmid=17178922|url=http://pediatrics.aappublications.org/cgi/content/full/119/1/e275}}</ref> Estimates vary widely for the [[Incidence (epidemiology)|incidence]] of these complications,<ref name=Gouveia/> and the actual incidence is unknown, due to high levels of underreporting and to the difficulty of linking manipulation to adverse effects such as [[stroke]].<ref name=Ernst-adverse/> Adverse effects are poorly reported in recent studies investigating chiropractic manipulations.<ref name=Ernst-2012>{{cite journal|journal=N Z Med J|year=2012|volume=125|issue=1353|pages=87–140|title= Reporting of adverse effects in randomised clinical trials of chiropractic manipulations: a systematic review|author= Ernst E, Posadzki P|pmid=22522273|url=|pmc=}}</ref>
{{Main|Chiropractic education|List of chiropractic schools}}
The entry criteria, structure, teaching methodology and nature of Chiropractic programs offered at Chiropractic schools vary considerably around the world. To help standardize and ensure quality of Chiropractic education, in 2005 the World Health Organization published guidelines for basic training and safety in Chiropractic. <ref name=WHO>http://www.who.int/medicines/areas/traditional/Chiro-Guidelines.pdf</ref> In general, the World Health Organization lists three potential educational paths involving full‐time chiropractic education across the globe. This includes: 1 – 4 years of pre-requisite training in basic sciences at university level followed by a 4 year full‐time Doctorate program; DC. A 5 year integrated bachelor degree; BSc (Chiro). A 2 - 3 year Masters program following the completion of a bachelor degree; MSc (Chiro)<ref name=WHO-guidelines/> as well MTech (Chiro), a Masters of Technology in Chiropractic.<ref>{{cite web |url=http://www.chiropractic.co.za/index.html?lf=1;pg=14 |title=CASA : Student Info |accessdate=2009-10-19 }}</ref>


Regardless of the model of education utilized, prospective chiropractors without relevant prior health care education or experience, must spend no less than 4200 student/teacher contact hours (or the equivalent) in four years of full‐time education. This includes a minimum of 1000 hours of supervised clinical training.<ref name=WHO-guidelines>{{cite journal |author= World Health Organization |year=2005 |title= WHO guidelines on basic training and safety in chiropractic |url=http://www.who.int/medicines/areas/traditional/Chiro-Guidelines.pdf |format=PDF |accessdate=2008-03-03}}</ref> Health professionals with advanced clinical degrees, such as medical doctors, can meet the educational and clinical requirements to practice as a chiropractor in 2200 hours, which is most commonly done in countries where the profession is in its infancy.<ref name=WHO /> Upon meeting all clinical and didactic requirements of chiropractic school, a degree in chiropractic medicine is granted. However, in order to legally practice, chiropractors, like all [[regulated|self regulated]] health care professionals, must be [[licensed]].
Rate for adverse events varied between 33% and 60.9%. The study reported frequency of serious adverse effect as between strokes 50 per 100,000, 1.46 per 10milloin serious adverse events and death rate of 2.68 per 10 million, though it was determined that there was inadequate data to be conclusive.<ref name=Gouveia/>

Several case reports show temporal associations between interventions and potentially serious complications.<ref name=Hurwitz-2008/> The published medical literature contains reports of 26 deaths since 1934 following chiropractic manipulations and many more seem to remain unpublished.<ref name=Ernst-death/> [[Vertebrobasilar artery stroke]] is [[Association (statistics)|statistically associated]] with chiropractic services in persons under 45 years of age,<ref>{{cite journal|last=Cassidy|first=JD|coauthors=Boyle, E; Côté, P; He, Y; Hogg-Johnson, S; Silver, FL; Bondy, SJ|title=Risk of vertebrobasilar stroke and chiropractic care: results of a population-based case-control and case-crossover study.|journal=Spine|date=15|year=2008|month=Feb|volume=33|issue=4 Suppl|pages=S176-83|pmid=18204390|accessdate=2 December 2012}}</ref> but it is similarly associated with general practitioner services, suggesting that these associations are likely explained by preexisting conditions.<ref name=Hurwitz-2008>{{cite journal|journal=Spine|year=2008|volume=33|issue= 4 Suppl|pages=S123–52|title= Treatment of neck pain: noninvasive interventions: results of the Bone and Joint Decade 2000–2010 Task Force on Neck Pain and Its Associated Disorders|author= Hurwitz EL, Carragee EJ, van der Velde G ''et al.''|doi=10.1097/BRS.0b013e3181644b1d|pmid=18204386}}</ref><ref>{{cite journal|author= Paciaroni M, Bogousslavsky J|title= Cerebrovascular complications of neck manipulation|journal= Eur Neurol|volume=61|issue=2|pages=112–8|year=2009|pmid=19065058|doi=10.1159/000180314|url=http://content.karger.com/ProdukteDB/produkte.asp?Aktion=ShowFulltext&ArtikelNr=180314&ProduktNr=223840}}</ref> Weak to moderately strong evidence supports causation (as opposed to statistical association) between [[cervical manipulation|cervical manipulative therapy]] and vertebrobasilar artery stroke.<ref>{{cite journal|journal=[[The Neurologist|Neurologist]]|year=2008|volume=14|issue=1|pages=66–73|title= Does cervical manipulative therapy cause vertebral artery dissection and stroke?|author= Miley ML, Wellik KE, Wingerchuk DM, Demaerschalk BM|doi=10.1097/NRL.0b013e318164e53d|pmid=18195663}}</ref> A 2012 systematic review determined that there is insufficient evidence to support a strong association or no association between cervical manipulation and stroke.<ref name=Haynes>{{cite journal|journal=International Journal of Clinical Practice|year=2012|volume=66|issue=10|pages=940–947|title= Assessing the risk of stroke from neck manipulation: a systematic review|author= Haynes MJ, Vincent K, Fischhoff C, Bremner AP, Lanlo O, Hankey GJ.|doi=10.1111/j.1742-1241.2012.03004.x|pmid=22994328|url=http://onlinelibrary.wiley.com/doi/10.1111/j.1742-1241.2012.03004.x/full}}</ref>

Chiropractors, like other primary care providers, sometimes employ diagnostic imaging techniques such as [[Radio diagnostics|X-rays]] and [[CT scan]]s that rely on [[ionizing radiation]].<ref name=Bussieres/> Although there is no clear evidence for the practice, some chiropractors may still X-ray a patient several times a year.<ref name=Trick-or-Treatment/> Research suggests that most chiropractors in Canada are taught and follow stringent radiography guidelines,<ref>{{cite journal|journal=Spine|year=2007|volume=32|issue=22|pages=2509–2514|title=Do chiropractors adhere to guidelines for back radiographs? A study of chiropractic teaching clinics in Canada|author= Ammendolia C, Côté P, Hogg-Johnson S, Bombardier C|doi= 10.1097/BRS.0b013e3181578dee|pmid=18090093}}</ref> which were developed to reduce unnecessary radiography.<ref name=Bussieres>{{cite journal|author=Bussières AE, Taylor JAM, Peterson C|title=Diagnostic imaging practice guidelines for musculoskeletal complaints in adults—an evidence-based approach—part 3: spinal disorders|journal=J Manipulative Physiol Ther|volume=31|issue=1|pages=33–88|year=2008|pmid=18308153|doi=10.1016/j.jmpt.2007.11.003|url=http://jmptonline.org/article/S0161-4754(07)00314-4/fulltext }}</ref>

===Risk-benefit===
A 2012 [[systematic review]] concluded that no accurate assessment of risk-benefit exists for cervical manipulation.<ref name=Haynes>{{cite journal|journal=International Journal of Clinical Practice|year=2012|volume=66|issue=10|pages=940–947|title= Assessing the risk of stroke from neck manipulation: a systematic review|author= Haynes MJ, Vincent K, Fischhoff C, Bremner AP, Lanlo O, Hankey GJ.|doi=10.1111/j.1742-1241.2012.03004.x|pmid=22994328|url=http://onlinelibrary.wiley.com/doi/10.1111/j.1742-1241.2012.03004.x/full}}</ref> A 2010 systematic review stated that there is no good evidence to assume that neck manipulation is an effective treatment for any medical condition and suggested a [[precautionary principle]] in healthcare for chiropractic intervention even if a causality with [[vertebral artery dissection]] after neck manipulation were merely a remote possibility.<ref name=Ernst-death>{{cite journal|journal= Int J Clinical Practice|year=2010|volume=64|issue= 8|pages=1162–1165|title= Deaths after chiropractic: a review of published cases|author= E Ernst|pmid=20642715|doi=10.1111/j.1742-1241.2010.02352.x}}</ref> The same review concluded that the risk of death from manipulations to the neck outweighs the benefits.<ref name=Ernst-death/> Chiropractors have criticized this conclusion.<ref name=Ernst-response>{{cite journal|journal= Int J Clin Pract|year=2011|volume=65|issue= 1|page=106|title= Response to critiques of deaths after chiropractic|author= E Ernst|pmid=21155949|doi=10.1111/j.1742-1241.2010.02568.x}}</ref>

A 2009 review evaluating maintenance chiropractic care found that spinal manipulation is routinely associated with considerable harm and no compelling evidence exists to indicate that it adequately prevents symptoms or diseases, thus the risk-benefit is not evidently favorable.<ref>{{cite journal|journal= Prev Med|year=2009|volume=49|issue=2–3|pages=99–100|title= Chiropractic maintenance treatment, a useful preventative approach?|author= Ernst E|doi=10.1016/j.ypmed.2009.05.004|pmid=19465044}}</ref>

A 2008 summary found that the best evidence suggests that chiropractic care is a useful therapy for subjects with neck or low-back pain for which the risks of serious adverse events should be considered negligible.<ref>{{cite journal|doi= 10.1016/j.jmpt.2008.06.001|journal= J Manipulative Physiol Ther|year=2008|volume=31|issue= 6|pages=461–464|title= Adverse events following chiropractic care for subjects with neck or low-back pain: do the benefits outweigh the risks?|author= Rubinstein SM|pmid=18722202 }}</ref> A 2007 systematic review found that with uncertain efficacy and definite risks, the risk-benefit balance of spinal manipulation can't be positive.<ref name=Ernst-adverse/> A 2006 systematic review of systematic reviews found the risk-benefit balance does not favor spinal manipulation over other treatments like [[physical therapy]].<ref name=Ernst-Canter/>

===Cost-effectiveness===
A 2012 systematic review suggested that the use of spine manipulation in clinical practice is a cost-effective treatment when used alone or in combination with other treatment approaches.<ref>{{cite journal|journal= J Electromyogr Kinesiol|year=2012|volume=|issue=|pages=|title=Spinal manipulation epidemiology: Systematic review of cost effectiveness studies|author= Michaleff ZA, Lin CW, Maher CG, van Tulder MW|doi= 10.1016/j.jelekin.2012.02.011|pmid=22429823|pmc= }}</ref> A 2011 systematic review found evidence supporting the cost-effectiveness of using spinal manipulation for the treatment of sub-acute or chronic low back pain; the results for acute low back pain were inconsistent.<ref>{{cite journal|journal= European Spine Journal|year=2011|volume=20|issue=7|pages=1024–1038|title=Cost-effectiveness of guideline-endorsed treatments for low back pain: a systematic review|author= Lin CW, Haas M, Maher CG, Machado LA, van Tulder MW|doi=10.1007/s00586-010-1676-3|pmid=21229367|pmc= 3176706 }}</ref> A 2006 qualitative review found that the research literature suggests that chiropractic obtains at least comparable outcomes to alternatives with potential cost savings.<ref>{{cite journal|journal= J Manipulative Physiol Ther|year=2006|volume=29|issue=9|pages=707–25|title= Health services research related to chiropractic: review and recommendations for research prioritization by the chiropractic profession|author= Mootz RD, Hansen DT, Breen A, Killinger LZ, Nelson C|doi=10.1016/j.jmpt.2006.09.001|pmid=17142165}}</ref>


All Chiropractic Examining Boards require candidates to complete a 12 month clinical internship to obtain licensure. Licensure is granted following successful completion of all state/provincial and national board exams so long as the chiropractor maintains [[malpractice]] insurance. Nonetheless, there still some variations in educational standards internationally depending on admission and graduation requirements. chiropractic medicine is regulated in North America by state/provincial [[statute]]. The regulatory boards are responsible for protecting the public, standards of practice, disciplinary issues, quality assurance and maintenance of competency.<ref>[http://www.ccachiro.org/Client/cca/cca.nsf/web/Facts%20%26%20FAQs?OpenDocument Facts & FAQs<!-- Bot generated title -->]</ref>
A 2006 systematic [[cost-effectiveness]] review found that the reported cost-effectiveness of chiropractic manipulation in the [[United Kingdom]] compared favorably with other treatments for back pain, but that reports were based on data from clinical trials without sham controls and that the specific cost-effectiveness of the treatment (as opposed to [[non-specific effect]]s) remains uncertain.<ref>{{cite journal|journal= [[Evid Based Complement Alternat Med]]|year=2006|volume=3|issue=4|pages=425–32|title= Cost-Effectiveness of Complementary Therapies in the United Kingdom—A Systematic Review†|author= Canter PH, Coon JT, Ernst E|doi=10.1093/ecam/nel044|pmid=17173105|url=http://ecam.oxfordjournals.org/cgi/content/full/3/4/425|pmc= 1697737}}</ref> A 2005 American systematic review of economic evaluations of conservative treatments for low back pain found that significant quality problems in available studies meant that definite conclusions could not be drawn about the most cost-effective intervention.<ref>{{cite journal|journal= [[Best Pract Res Clin Rheumatol]]|year=2005|volume=19|issue=4|pages=671–84|title= What is the most cost-effective treatment for patients with low back pain? a systematic review|author= van der Roer N, Goossens MEJB, Evers SMAA, van Tulder MW|doi=10.1016/j.berh.2005.03.007|pmid=15949783}}</ref> The cost-effectiveness of maintenance chiropractic care is unknown.<ref name=Leboeuf-Yde-C/>


==Ethics and medicolegal issues==
Gleberzon ''et al.'' identify "deliberate fraud" as a notably harmful element of the chiropractic profession, finding that dubious practice techniques can translate into "outlandish billing and utilization rates". Those at the "fringe of ethical behavior" present the profession with a challenge, they believe, and must be weeded out.<ref name="Gleberzon2005">{{cite journal
Chiropractors, like other health care professionals, are self-regulated and have a [[fiduciary]] responsibility to protect the public and ensure competent, professional and ethical behaviour. Chiropractors have been noted to have increased instances of fraud, abuse and quackery compared to other health professions.<ref name=Murphy-pod>{{cite journal|pmid=18759966|doi=10.1186/1746-1340-16-10|url=http://chiroandosteo.com/content/pdf/1746-1340-16-10.pdf|year=2008|month=Aug|last1=Murphy|first1=DR|last2=Schneider|last3=Seaman|last4=Perle|last5=Nelson|title=How can chiropractic become a respected mainstream profession? The example of podiatry|volume=16|page=10|journal=Chiropractic & osteopathy|first2=MJ|first3=DR|first4=SM|first5=CF|pmc=2538524}}</ref> Internal criticism identified dubious practice techniques that promote high-volume treatments (which can increase dependency) and far-reaching and outlandish claims regarding the clinical significance of joint dysfunction/subluxation and its role in health and disease<ref name="Gleberzon2005">{{cite journal
|first1=Brian J.
|first1=Brian J.
|last1=Gleberzon
|last1=Gleberzon
Line 300: Line 150:
|volume=49
|volume=49
|issue=2
|issue=2
}}</ref> As opposed to earlier in its history when founder D.D. Palmer claimed that spinal dysfunction/subluxation was the cause of all disease, modern chiropractic instituions and the international chiropractic educational accrediting agency (CCEI) has disavowed the the monocausal theory of joint dysfunction/subluxation.<ref name="Henderson 2012 632–642">{{cite journal|last=Henderson|first=C.N.R|journal=Journal of Electromyography and Kinesiology|year=2012|month=October|volume=22|issue=5|pages=632–642|accessdate=27 January 2013}}</ref>
}}</ref>


==Public health==
===Regulation===
Since its inception, chiropractic was controversial amongst the established medical orthodoxy. Chiropractors were jailed for "practicing medicine without a license" which the profession designed a legal and political defence against prosecution arguing that chiropractic was "separate and distinct from medicine", asserting that chiropractors "analyzed" rather than "diagnosed", and "adjusted" subluxations rather than "treated" disease.<ref name=History-Primer/> In 1963 the American Medical Association formed a "Committee on Quackery" designed to "contain and eliminate" the chiropractic profession. In 1966, the AMA referred to chiropractic an "unscientific cult" and until 1980 and held that it was unethical for medical doctors to associate themselves with "unscientific practitioners".<ref name=Chiro-PH>{{cite journal |journal= J Manipulative Physiol Ther |year=2008 |volume=31 |issue=6 |pages=397–410 |title= Chiropractic and public health: current state and future vision |author= Johnson C, Baird R, Dougherty PE ''et al.'' |doi=10.1016/j.jmpt.2008.07.001 |pmid=18722194 |url=http://jmptonline.org/article/PIIS0161475408001784/fulltext}}</ref> The 1987, the AMA was found guilty of being engaged in an unlawful conspiracy in restraint of trade "to contain and eliminate the chiropractic profession." <ref name=History-Primer/> In the 1980s, spinal manipulation gained mainstream recognition<ref>{{cite web |url=http://muaphysicians.com/historical.html |publisher= International MUA Academy of Physicians |title= Manipulation under anesthesia: historical considerations |author= Francis RS |year=2005 |accessdate=2008-07-06}}</ref> and has spurred ongoing collaboration into research of manipulative therapies and models of delivery of chiropractic care for musculoskeletal conditions in the mainstream healthcare sector.<ref name="DeVocht-JW">{{cite journal|journal=Clin Orthop Relat Res|year=2006|volume=444|pages=243–9|title=History and overview of theories and methods of chiropractic: a counterpoint|author=DeVocht JW|doi=10.1097/01.blo.0000203460.89887.8d|pmid=16523145 }}</ref><ref>{{cite journal|coauthors=Mior S, Barnsley J, Boon H, Ashbury FD, Haig R.|title=Designing a framework for the delivery of collaborative musculoskeletal care involving chiropractors and physicians in community-based primary care.|journal=J Interprof Care|year=2010|month=Nov|volume=24|issue=6|pages=678–89|pmid=20441400|accessdate=4 February 2013}}</ref><ref>{{cite journal|coauthors=Mior S, Gamble B, Barnsley J, Côté P, Côté E.|title=Changes in primary care physician's management of low back pain in a model of interprofessional collaborative care: an uncontrolled before-after study.|journal=Chiropr Man Therap|year=2013|month=Feb|volume=21|issue=1|accessdate=4 February 2013}}</ref>
{{further2|[[Vaccine controversy#Alternative medicine|Vaccine controversy and alternative medicine]]|[[Water fluoridation controversy]]}}
===Public health===
Some chiropractors oppose [[vaccination]] and [[water fluoridation]], which are common [[public health]] practices.<ref name=Murphy-pod/> Within the chiropractic community there are significant disagreements about vaccination,<ref name=Busse/><ref name=Campbell/> one of the most cost-effective public health interventions available.<ref>{{cite journal|author= Ehreth J|title= The global value of vaccination|journal=Vaccine|volume=21|issue=7–8|pages=596–600|year=2003|pmid=12531324|doi=10.1016/S0264-410X(02)00623-0}}</ref> Most chiropractic writings on vaccination focus on its negative aspects,<ref name=Busse/> claiming that it is hazardous, ineffective, and unnecessary.<!--<ref name=Campbell/> --> Some chiropractors have embraced vaccination, but a significant portion of the profession rejects it, as original chiropractic philosophy traces diseases to causes in the spine and states that vaccines interfere with healing.<ref name=Campbell/>
Public health is becoming an increasingly important topic for chiropractors and what role they may play in the public health arena with recommendations suggesting the natural focus for the chiropractic profession is maintaining spinal and musculoskeletal health, good nutrition and an active lifestyle from childhood and throughout life, thereby promoting general health and freedom from chronic pain, disease and disability.<ref>{{cite journal|last=Johnson|first=C|coauthors=Rubinstein Sm, Cote P, et al. (2012) Chiropractic Care and Public Health: Answering Difficult Questions About Safety, Care Through|title=Chiropractic Care and Public Health: Answering Difficult Questions About Safety, Care Through the Lifespan, and Community Action.|journal=JMPT|year=2012|volume=35|pages=494–513|doi=10.1016/j.jmpt.2012.09.001.|pmid=23069244|accessdate=26 January 2013}}</ref> However, traditionally chiropractic has not endorsed mainstream public health measures such as mandatory [[vaccination]] and [[water fluoridation]] stating the patient should be able to freely choose for themselves.<ref name=Campbell/><ref name=Campbell>{{cite journal|journal=Pediatrics|year=2000|volume=105|issue=4|pages=e43|title= Chiropractors and vaccination: a historical perspective|author= Campbell JB, Busse JW, Injeyan HS|pmid=10742364|url=http://pediatrics.aappublications.org/cgi/content/full/105/4/e43|doi= 10.1542/peds.105.4.e43}}</ref><ref name=Busse>{{cite journal|journal= J Manipulative Physiol Ther|year=2005|volume=28|issue=5|pages=367–73|title= Chiropractic antivaccination arguments|author= Busse JW, Morgan L, Campbell JB|doi=10.1016/j.jmpt.2005.04.011|pmid=15965414|url= http://jmptonline.org/article/S0161-4754(05)00111-9/fulltext}}</ref>
<ref>{{cite journal|journal= Am J Public Health|year=1989|volume=79|issue=10|pages=1405–8|title= Fluoridation referendum in La Crosse, Wisconsin: contributing factors to success|author= Jones RB, Mormann DN, Durtsche TB|pmid=2782512|pmc=1350185|url=http://www.ajph.org/cgi/reprint/79/10/1405.pdf|format=PDF|doi= 10.2105/AJPH.79.10.1405}}</ref>


===Diagnostic imaging===
The extent to which anti-vaccination views sustain the current chiropractic profession is uncertain.<ref name=Busse/> The [[American Chiropractic Association]] and the International Chiropractors Association support individual exemptions to compulsory vaccination laws, and a 1995 survey of U.S. chiropractors found that about a third believed there was no scientific proof that immunization prevents disease.<ref name=Campbell>{{cite journal|journal=Pediatrics|year=2000|volume=105|issue=4|pages=e43|title= Chiropractors and vaccination: a historical perspective|author= Campbell JB, Busse JW, Injeyan HS|pmid=10742364|url=http://pediatrics.aappublications.org/cgi/content/full/105/4/e43|doi= 10.1542/peds.105.4.e43}}</ref> The [[Canadian Chiropractic Association]] supports vaccination;<ref name=Busse>{{cite journal|journal= J Manipulative Physiol Ther|year=2005|volume=28|issue=5|pages=367–73|title= Chiropractic antivaccination arguments|author= Busse JW, Morgan L, Campbell JB|doi=10.1016/j.jmpt.2005.04.011|pmid=15965414|url= http://jmptonline.org/article/S0161-4754(05)00111-9/fulltext}}</ref> a survey in Alberta in 2002 found that 25% of chiropractors advised patients for, and 27% against, vaccinating themselves or their children.<ref>{{cite journal|author= Russell ML, Injeyan HS, Verhoef MJ, Eliasziw M|title= Beliefs and behaviours: understanding chiropractors and immunization|journal=Vaccine|volume=23|issue=3|pages=372–9|year=2004|pmid=15530683|doi=10.1016/j.vaccine.2004.05.027}}</ref>
Chiropractors employ diagnostic imaging techniques such as [[Radio diagnostics|X-rays]] and [[CT scan]]s to assist in the management of patient care. External and internal criticism regarding the frequency and inappropriate use of X-Rays, such as full spine radiographs, resulted in the development of evidence-based general practice guidelines in 2007 to improve patient safety by eliminating unnecessary exposure to radiation.<ref name=Bussieres>{{cite journal|author=Bussières AE, Taylor JAM, Peterson C|title=Diagnostic imaging practice guidelines for musculoskeletal complaints in adults—an evidence-based approach—part 3: spinal disorders|journal=J Manipulative Physiol Ther|volume=31|issue=1|pages=33–88|year=2008|pmid=18308153|doi=10.1016/j.jmpt.2007.11.003|url=http://jmptonline.org/article/S0161-4754(07)00314-4/fulltext }}</ref><ref>{{cite journal|journal=Spine|year=2007|volume=32|issue=22|pages=2509–2514|title=Do chiropractors adhere to guidelines for back radiographs? A study of chiropractic teaching clinics in Canada|author= Ammendolia C, Côté P, Hogg-Johnson S, Bombardier C|doi= 10.1097/BRS.0b013e3181578dee|pmid=18090093}}</ref>


===Safety===
Early opposition to water fluoridation included chiropractors, some of whom continue to oppose it as being incompatible with chiropractic philosophy and an infringement of personal freedom. Other chiropractors have actively promoted fluoridation, and several chiropractic organizations have endorsed scientific principles of public health.<ref>{{cite journal|journal= Am J Public Health|year=1989|volume=79|issue=10|pages=1405–8|title= Fluoridation referendum in La Crosse, Wisconsin: contributing factors to success|author= Jones RB, Mormann DN, Durtsche TB|pmid=2782512|pmc=1350185|url=http://www.ajph.org/cgi/reprint/79/10/1405.pdf|format=PDF|doi= 10.2105/AJPH.79.10.1405}}</ref>
There has been considerable debate on the safety of spinal manipulation, the core clinical act of chiropractors, in particular with the cervical spine.<ref name=Ernst-adverse/> Adverse events in SM studies are believed to be under-reported <ref name=Ernst-2012>{{cite journal|journal=N Z Med J|year=2012|volume=125|issue=1353|pages=87–140|title= Reporting of adverse effects in randomised clinical trials of chiropractic manipulations: a systematic review|author= Ernst E, Posadzki P|pmid=22522273|url=|pmc=}}</ref> and appear to be more common following HVLA manipulation than mobilization.<ref name="Hurwitz EL, Morgenstern H, Vassilaki M, Chiang LM 2005 1477–84"/>

Although serious injuries and fatal consequences can occur and may be under-reported,<ref name=Ernst-death/> these are generally considered to be rare when spinal manipulation is employed skillfully and appropriately.<ref name=WHO-guidelines/> There is ongoing research investigating upper cervical manipulation and incidence of stroke.<ref name=Haynes>{{cite journal|journal=International Journal of Clinical Practice|year=2012|volume=66|issue=10|pages=940–947|title= Assessing the risk of stroke from neck manipulation: a systematic review|author= Haynes MJ, Vincent K, Fischhoff C, Bremner AP, Lanlo O, Hankey GJ.|doi=10.1111/j.1742-1241.2012.03004.x|pmid=22994328|url=http://onlinelibrary.wiley.com/doi/10.1111/j.1742-1241.2012.03004.x/full}}</ref>
In addition to traditional chiropractic opposition to water fluoridation and vaccination, chiropractors' attempts to establish a positive reputation for their public health role are also compromised by their reputation for recommending repetitive lifelong chiropractic treatment.<ref name=Murphy-pod/>

==Controversy and criticism==
{{Main|Chiropractic controversy and criticism}}
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Throughout its history chiropractic has been the subject of internal and external controversy and criticism.<ref name=Kaptchuk-Eisenberg>{{cite journal|pmid=9818801|year=1998|month=Nov|last1=Kaptchuk|first1=TJ|last2=Eisenberg|title=Chiropractic: origins, controversies, and contributions|volume=158|issue=20|pages=2215–24|issn=0003-9926|journal=Archives of Internal Medicine|url=http://archinte.ama-assn.org/cgi/pmidlookup?view=long&pmid=9818801|doi=10.1001/archinte.158.20.2215|first2=DM}}{{dead link|date=June 2012}}</ref><ref name=Jaroff>{{cite news|last=Jaroff|first=Leon|title=Back Off, Chiropractors!|url=http://www.time.com/time/columnist/jaroff/article/0,9565,213482,00.htm|date=27 February 2002|work=[[Time (magazine)|Time]]|accessdate=7 June 2009}}</ref> According to [[Daniel D. Palmer]], the founder of chiropractic, [[vertebral subluxation|subluxation]] is the sole cause of disease and manipulation is the cure for all diseases of the human race.<ref name=Ernst-eval>{{cite journal|pmid=18280103|year=2008|month=May|last1=Ernst|first1=E|title=Chiropractic: a critical evaluation|volume=35|issue=5|pages=544–62|issn=0885-3924|doi=10.1016/j.jpainsymman.2007.07.004|journal=Journal of pain and symptom management}}</ref> A critical evaluation stated "Chiropractic is rooted in mystical concepts. This led to an internal conflict within the chiropractic profession, which continues today."<ref name=Ernst-eval/> Chiropractors, including D.D. Palmer, were [[jail]]ed for [[Practicing medicine without license|practicing medicine without a license]].<ref name=Ernst-eval/> For most of its existence, chiropractic has battled with [[mainstream medicine]], sustained by [[antiscientific]] and [[pseudoscientific]] ideas such as subluxation.<ref name=History-Primer>{{cite web|title= Chiropractic history: a primer|author= [[Joseph C. Keating, Jr.]], Cleveland CS III, Menke M|url=http://data.memberclicks.com/site/ahc/ChiroHistoryPrimer.pdf|format=PDF|year=2005|accessdate=2008-06-16|publisher= Association for the History of Chiropractic|quote=A significant and continuing barrier to scientific progress within chiropractic are the anti-scientific and pseudo-scientific ideas (Keating 1997b) which have sustained the profession throughout a century of intense struggle with political medicine. Chiropractors' tendency to assert the meaningfulness of various theories and methods as a counterpoint to allopathic charges of quackery has created a defensiveness which can make critical examination of chiropractic concepts difficult (Keating and Mootz 1989). One example of this conundrum is the continuing controversy about the presumptive target of DCs' adjustive interventions: subluxation (Gatterman 1995; Leach 1994).}}</ref> Chiropractic has been controversial, though to a lesser extent than in past years.<ref name="DeVocht-JW">{{cite journal|journal=Clin Orthop Relat Res|year=2006|volume=444|pages=243–9|title=History and overview of theories and methods of chiropractic: a counterpoint|author=DeVocht JW|doi=10.1097/01.blo.0000203460.89887.8d|pmid=16523145 }}</ref> The American Medical Association has long been particularly critical, as indicated by a 1966 targeting of chiropractors described as a "national campaign against medical quackery."<ref>http://news.google.com/newspapers?id=_hcfAAAAIBAJ&sjid=F5sEAAAAIBAJ&pg=6974,3060990&dq=chiropractor+quack&hl=en</ref>

Chiropractic authors have stated that fraud, abuse and [[quackery]] are more prevalent in chiropractic than in other health care professions.<ref name=Murphy-pod>{{cite journal|pmid=18759966|doi=10.1186/1746-1340-16-10|url=http://chiroandosteo.com/content/pdf/1746-1340-16-10.pdf|year=2008|month=Aug|last1=Murphy|first1=DR|last2=Schneider|last3=Seaman|last4=Perle|last5=Nelson|title=How can chiropractic become a respected mainstream profession? The example of podiatry|volume=16|page=10|journal=Chiropractic & osteopathy|first2=MJ|first3=DR|first4=SM|first5=CF|pmc=2538524}}</ref> Unsubstantiated claims about the efficacy of chiropractic have continued to be made by individual chiropractors and chiropractic associations.<!-- <ref name=Ernst-eval/> --> The core concept of traditional chiropractic, [[vertebral subluxation]], is not based on [[sound science]].<!-- <ref name=Ernst-eval/> --> The biomechanical listing systems taught in chiropractic college technique offerings have been criticized as inaccurate, inadequate and invalid.<ref name=Harrison3dlistpart1>{{cite journal|last=Harrison|first=DE|title=Three-dimensional spinal coupling mechanics: Part I. A review of the literature.|journal=J Manipulative Physiol Ther.|year=1998|month=Feb|volume=21|issue=2|pages=101–13|pmid=9502066}}</ref> A critical evaluation found that research has not demonstrated that [[spinal manipulation]], the main treatment method employed by chiropractors, is [[Efficacy#Healthcare|effective]] for any medical condition, with the possible exception of treatment for [[back pain]].,<ref name=Ernst-eval/> whereas, another review found manual therapies in general to be effective for back pain, neck pain, some forms of headaches and some extremity joint conditions.<ref name="Bronfort-Haas"/> Although rare,<ref name=WHO-guidelines>[http://www.who.int/medicines/areas/traditional/Chiro-Guidelines.pdf WHO guidelines on basic training and safety in chiropractic - 2005]</ref> spinal manipulation, particularly on the upper spine, can also result in complications that can lead to permanent disability or death; these can occur in adults<ref name=Ernst-adverse>{{cite journal|pmid=17606755|doi=10.1258/jrsm.100.7.330|laysummary=http://www.medicalnewstoday.com/articles/75754.php|laysource=Med News Today|laydate=2 July 2007|year=2007|month=Jul|last1=Ernst|first1=E|title=Adverse effects of spinal manipulation: a systematic review|volume=100|issue=7|pages=330–8|issn=0141-0768|journal=Journal of the Royal Society of Medicine|pmc=1905885}}</ref> and children.<ref name=Vohra>{{cite journal|doi=10.1542/peds.2006-1392|pmid=17178922|year=2007|month=Jan|last1=Vohra|first1=S|last2=Johnston|last3=Cramer|last4=Humphreys|title=Adverse events associated with pediatric spinal manipulation: a systematic review|volume=119|issue=1|pages=e275–83|issn=0031-4005|journal=Pediatrics|url=http://pediatrics.aappublications.org/cgi/pmidlookup?view=long&pmid=17178922|first2=BC|first3=K|first4=K}}</ref>


==References==
==References==
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{{Chiropractic}}
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[[Category:Medicine]]
[[Category:Alternative medicine]]
[[Category:Alternative medicine]]
[[Category:Chiropractic]]
[[Category:Chiropractic]]
[[Category:Manipulative therapy]]
[[Category:Healthcare occupations]]
[[Category:Healthcare occupations]]
[[Category:Therapy]]
[[Category:Therapy]]
[[Category:Physical exercise]]
[[Category:Manipulative therapy]]


[[ar:معالجة يدوية]]
[[ar:معالجة يدوية]]

Revision as of 01:54, 11 February 2013


Chiropractic is health care profession concerned with the structural diagnosis, treatment and prevention of disorders of the neuromusculoskeletal system and the effects of these disorders on general health. There is an emphasis on manual and manipulative therapy and its role in joint dysfunction/subluxation . Currently, chiropractic medicine is regulated and practiced in over 100 countries, however chiropractors are most prevalent in North America, Australia and parts of Europe.[1] The majority of mainstream health care and governmental organizations classify chiropractic as traditional/complementary alternative medicine[2] Most people who seek chiropractic care do so for primarily for low back pain and other neuromusculoskeletal complaints.[3]

Chiropractic was founded in 1895 by magnetic healer, D.D. Palmer, in Davenport, Iowa, United States. Chiropractic theory on spinal joint dysfunction/subluxation and its putative role in non-musculoskeletal disease has been a source of controversy since its inception in 1895. The controversy is due in part to chiropractic's vitalistic and metaphysical origins, and use of terminology that is not always amenable to scientific investigation. Far reaching claims and lack of scientific evidence supporting spinal joint dysfunction/subluxation as the sole cause of disease has led to a critical evaluation of a central tenet of chiropractic and the appropriateness of the profession's role in treating a broad spectrum of disorders that are unrelated to the neuromusculoskeletal system.[4] Although there is external and internal debate within the chiropractic profession regarding the clinical significance of joint dysfunction/subluxation,[5] the manipulable lesion remains inextricably linked to the profession as basis for spinal manipulation.[6]

Manual and conservative therapies commonly used by chiropractors are effective for the treatment of low back pain,[7][8] and might also be effective for the treatment of lumbar disc herniation with radiculopathy,[9][10] neck pain,[11] some forms of headache,[12][13] and some extremity joint conditions.[14][15] There is insufficient evidence or known mechanisms for effects of chiropractic manipulation on non-musculoskeletal conditions.[16] The efficacy and cost-effectiveness of maintenance chiropractic care are unknown. [17] A 2011 study, however, demonstrated that maintenance spinal manipulative therapy is effective for the treatment of chronic nonspecific low back pain.[18] There has been considerable debate over the safety of the core clinical act of chiropractors: spinal manipulation, particularly with the cervical spine.[19] Although serious injuries and fatal consequences can occur and may be under-reported,[20] these are generally considered to be rare when spinal manipulation is employed skillfully and appropriately.[1]


Scope of practice

Chiropractors emphasize the conservative management of the neuromusculoskeletal system without the use of medicines or surgery [1] with an emphasis on the spinal manipulation.[21] Chiropractors are generally regarded as primary contact, portal of entry health care providers. Although chiropractors have many attributes of primary care providers, chiropractic has more attributes of a limited medical specialty like dentistry or podiatry.[22] Chiropractors are licensed to communicate a neuromusculoskeletal diagnosis and order X-rays and may use broad diagnostic methods including skeletal imaging, observational and tactile assessments as well as orthopedic and neurological evaluation.[1] A chiropractor may also refer a patient to an appropriate specialist, or co-manage with another health care provider.[22] Common patient management involves spinal manipulation (SM) and other manual therapies to the joints and soft tissues, rehabilitative exercises, health promotion, electrical modalities, complementary procedures, and lifestyle counseling.[23] When indicated chiropractors may also refer a patient to an appropriate specialist, or co-manage with another health care provider.[22]

Due to the historical differences in philosophy and treatment approaches, there are range of 'broad' and 'narrow' scopes of practice for American chiropractors which tend to reflect 'straight' or 'mixer' underpinnings. [24] A focus on evidence-based research has also raised concerns that the resulting practice guidelines could limit the scope of chiropractic practice to treating backs and necks.[25] however the majority of chiropractors currently view themselves as "back/neck pain musculoskeletal specialists[26] The vast majority who seek chiropractic care do so for relief from back and neck pain and other neuromusculoskeletal complaints;[27]most do so specifically for low back pain.[3] Although it is generally accepted that chiropractic care is appropriate for musculoskeletal complaints, there is considerable debate on their role in treating visceral disorders..[28] Certain jurisdictions allows the practice animal chiropractic, whereby licensed chiropractors and veterinarians practice manual and manipulative therapies on animals for musculoskeletal disorders.[29] Increasing evidence-based practice and aligning with conventional medicine has been suggested to obtain more university affiliation and access to hospitals and long-term facilities; aligning with the CAM movement could bring more patients looking for nonmedical approaches.[30] In 2005, the World Health Organization developed chiropractic guidelines on basic training and safety to help standardize formal accreditation and licensure of chiropractors in countries where they remain unregulated. ,[1]. Currently, chiropractic medicine is regulated and practiced in over 100 countries, however chiropractors are most prevalent in North America, Australia and parts of Europe. The majority of mainstream health care and governmental organizations classify chiropractic as traditional or complementary alternative medicine[2]

History

Upon its founding 1895, chiropractic's early philosophy was rooted in vitalism, naturalism, magnetism, spiritualism and other constructs that were not amenable to the scientific method. Chiropractic's founder, D.D. Palmer, attempted to merge science and metaphysics.[31] In 1896, D.D. Palmer's first descriptions and underlying philosophy of chiropractic was strikingly similar to Andrew Still's principles of osteopathy established a decade earlier.[32] Both described the body as a "machine" whose parts could be manipulated to produce a drugless cure. Both professed the use of spinal manipulation on joint dysfunction/subluxation to improve health. Palmer drew further distinctions by noting that he was the first to use short-lever HVLA manipulative techniques using the spinous process and transverse processes as mechanical levers. Additionally he described the effects of chiropractic spinal manipulation was mediated by the nervous system in contrast to osteopathy who believed the effects were attributed to the supremacy of the circulatory system. [33] Palmer initially denied being trained by osteopathic medicine founder A.T. Still. But Palmer's papers, held at the Palmer College of Chiropractic, indicate that he wrote in 1899:

"Some years ago I took and expensive course in Electropathy, Cranial Diagnosis, Hydrotherapy, Facial Diagnosis. Later I took Osteopathy [which] gave me such a measure of confidence as to almost feel it unnecessary to seek other sciences for the mastery of curable disease. Having been assured that the underlying philosophy of chiropractic is the same as that of osteopathy...Chiropractic is osteopathy gone to seed."[31]

Despite their similarities, osteopathic practitioners sought to differentiate themselves by seeking licensure to regulate the profession calling chiropractic a "bastardized form of osteopathy"[32] In 1907 in a test of the new osteopathy law, a Wisconsin based chiropractor was charged with practicing osteopathic medicine without a license. Ironically the Palmers legal defence of chiropractic consisted of the first chiropractic textbook 'Modernized Chiropractic' published in 1906, written by "mixer" chiropractors Longworthy, Smith et al. who the Palmers despised. Although the chiropractors won their first test case in Wisconsin in 1907, prosecutions instigated by state medical boards became increasingly common and in many cases were successful. In response, chiropractors conducted political campaigns to secure separate licensing statutes, eventually succeeding in all fifty states, from Kansas in 1913 through Louisiana in 1974.[34] In this regard, chiropractic is unique with CAM disciplines in North America having achieved regulation in all American states and Canadian provinces.[26] By embracing both vitalism and materialism the philosophy of chiropractic has produced a diverse and eclectic mix of chiropractors which despite their emphasis of manual therapy they may vary on their perceived scope of practice, interventions and their role in the health care system.[35]

Philosophy

The philosophy of chiropractic shares both vitalistic and mechanistic viewpoints and embrace naturalistic principles that suggest decreased "host resistance" of the body facilitates the disease process and that natural interventions are preferable towards strengthening the host in its effort to optimize function and return to homeostasis.[36] The chiropractor's purpose is to foster the establishment and maintenance of an organism-environment dynamic that is the most conducive to functional well-being of the person as a whole.[36] Chiropractic care primarily emphasizes manipulation and other manual therapies as an alternative to medications and surgery.[37] The relationship between structure, especially the spine, and function as modulated by the nervous system, is central to chiropractic and its approach to the restoration and preservation of health. Chiropractors examine the biomechanics of the spine and other structures of the neuromusculoskeletal and its role in health and disease.[38] It is hypothesized that significant neurophysiological consequences may occur as a result of mechanical spinal functional disturbances, described by chiropractors as the vertebral subluxation complex[39] Most practitioners currently accept the importance of scientific research into chiropractic.[35] Foundational concepts of the philosophy of chiropractic include:

  • Vitalism accepts that all living organisms are sustained by a vital force that is both different from, and greater than, physical and chemical forces. Contemporary is it is referred to as "vis medicatrix naturae" (the healing power of nature).
  • Holism postulates that health is related to the balanced integration of the individual in all aspects and levels of being: body, mind and spirit, including interpersonal relationships and the interplay between lifestyle, environment, and health.
  • Naturalism states a preference for natural remedies. This is bound up with a set of philosophical principles which may be expressed as the body is built on nature’s order, it has natural ability to heal itself, that this is reinforced by the use of natural remedies, that it should not be tampered with unnecessarily through the use of drugs or surgery
  • Humanism is based on the postulate that individuals have immutable rights, for example the right to dignity. In CAM there is extensive concern about dehumanizing procedures and the dehumanizing institutions that have been created for the ill. Partly it is recognition of the personal, social and spiritual aspects of health and a move away from simply the biology of health.
  • Therapeutic Conservatism is the use therapies that have a low level of side effects and it tends to accept that the least care is the best care. This in some ways is derived from earlier principles. if the body is capable of healing itself, the role of the therapy is simply to initiate the process.[39]

"Straight" chiropractic

Half-length sitting portrait of man in his fifties with large gray beard and moustache, wearing coat and vest

Also known as 'subluxation-based' and 'principled chiropractic', chiropractors educated from this paradigm espouse traditional Palmer principles and philosophy. Historically straight chiropractors regarded spinal joint dsyfunction/subluxation as the primary cause of "dis-ease" and could be corrected via specific chiropractic adjustments. This monocausal view of disease has been abandoned by the profession [40] preferring a holistic view of subluxation that is viewed as theoretical construct in a"web of causation" along with other determinants of health.[6] Palmerian philosophy focused on metaphysical constructs such as Innate Intelligence and Universal Intelligence to explain the effects of the chiropractic adjustment, whose intent was the reduce/correct spinal subluxations and improving the functioning of the nervous system. The subluxation was said to be "the cause of 95 percent of all diseases... the other five percent is caused by displaced joints other than those of the vertebral column."[41] Misalignment of the vertebrae was believed to be cause impingement of the nerve root, a theory which has long been debunked[42] Subluxation-based chiropractors view traditional chiropractic lexicon such as "analysis" and "adjustment" and as a critical distinction of chiropractic despite lack of prevalence of these terms in the chiropractic literature[43] Subluxation-based chiropractors have been criticized both internally and externally for far-reaching claims of "killer" subluxations, pseudoscientific reasoning,[32] dogmatic approaches [44] unethical business practices that invoke religious themes and high-volume treatments for a variety of conditions that lack supportive scientific evidence.[45] This metaphysical and dogmatic and singular approach to chiropractic care has been criticized for failing to engage in critical and rational thinking and embracing evidence-based medicine.[46] Straight chiropractors use a subluxation-based model as opposed to the patient-centered model now favored in health care.[36] Although they are the minority within the profession, they are considered to have a disproportionate influence as "purists".[47]

"Mixer" chiropractic

Mixers form the majority of chiropractors and attempt to combine the materialistic reductionism of science with the metaphysics of their predecessors and with the holistic paradigm of wellness;[36] While D.D. Palmer considered vertebral misalignment to be the hallmark feature of subluxation, mixer pioneer Solon Langworthy asserted that intervertebral hypomobility, not misalignment, was subluxation’s cardinal biomechanical feature. This contrasting mechanistic emphasis, intervertebral misalignment vs. hypomobility, formed one the basis for a heated polemic in the profession. Although both misalignment and hypomobility are currently recognized as biomechanical features of subluxation, hypomobility has garnered much more attention in recent years.[6][48] Mixers were disdained by the Palmers who disapproved of their use of instrumentation and mixing chiropractic diagnostic and treatment approaches with osteopathic, naturopathic and allopathic viewpoints.[47] By embracing a mechanistic viewpoint, mixers are able balance the vitalistic notions with critical reasoning skills that led to legitimate scientific investigation of chiropractic principles. Mechanistic underpinnings have led to testable hypotheses that structure affects function via the nervous system by the scientific study of joint dysfunction (subluxation) and the biological mechanisms underlying manipulative therapies[35] Scientific chiropractors suggests that a mechanistic view will allow chiropractic care to become integrated into the wider health care community.[44] In contrast to subluxation-based chiropractors, evidence-based chiropractors favor and incorporate mainstream medical diagnostic and treatment approaches such as exercise, nutritional supplementation, rehabilitation, self-care, physiotherapeutic modalities, and other natural approaches. A majority of mixers retain belief that spinal dysfunction/subluxation may be involved in somato-visceral disorders. This group may represent the 'silent majority' of centrists who embrace evidence-based medicine but feel comfortable retaining elements of the subluxation complex that have not been validated through empirical evidence.[49]

Investigations

Spinal dysfunction/subluxation

Spinal dysfunction dubbed subluxation by chiropractors, is hypothesized to interfere with optimal biomechanics (structure) thereby altering proper neurological function. Chiropractic theory suggests spinal dysfunction/subluxation may contribute to neuromusculoskeletal and visceral disorders via aberrant spinal segmental and suprasegmental reflexes.[50]Chiropractors suggest spinal manipulation normalizes spine biomechanics, and as a consequence, normalizes afferent input to the central nervous system resulting in optimized neurological function and improved health outcomes.[51]

Chiropractic emphasis on mechanical joint dysfunction/subluxation and it's putative role in non-musculoskeletal disease has been a source of controversy since its inception in 1895 due its vitalistic and metaphysical origins which used terminology that was not amenable to scientific investigation. Far reaching claims and lack of scientific evidence supporting spinal joint dysfunction as the sole cause of disease has led to a critical evaluation of a central tenet of chiropractic and the appropriateness of the profession's role in treating a broad spectrum disorders that are not related to the neuromusculoskeletal system.[52] Today the monocausal view of disease has been abandoned by the profession [53]preferring a holistic view of subluxation that is viewed as theoretical construct in a "web of causation" along with other determinants of health.[6] Although there is external and internal debate within the chiropractic profession regarding the clinical significance of joint dysfunction/subluxation[54] the manipulable lesion remains inextricably linked to the profession as basis for spinal manipulation.[6]

Definitions

According to the ICD-10 the chiropractic subluxation is a biomechanical lesion or dysfunction in a joint or motion segment in which alignment, movement integrity and/or physiological function are altered, although contact between joint surfaces remains intact. It is essentially a functional entity, which may influence biomechanical and neural integrity.[55] It is also referred to as joint dysfunction, fixation, hypomobility, segmental and somatic dysfunction.

Theory

Although many theories have been put forth to explain the putative effects of subluxation that are reported in clinical practice, they may be broadly classified into three mechanism-oriented categories that are not mutually exclusive [56]

1. Encroachment of the intervertebral foramen (IVF) or spinal canal, the oldest and most widely known of these theories, proposes that subluxations cause bulging intervertebral discs, hypertrophied facet joint capsules, or enlarged intra-foraminal ligaments that encroach on pressure-sensitive IVF contents (e.g., dorsal root ganglia, nerve roots, and associated vascular elements) or the spinal canal and its contents (spinal cord, nerve roots and vascular plexus). Narrowing of the spinal canal and intervertebral foramen has been demonstrated in association with vertebral misalignments [57] Cadaveric and animal studies have shown that intervertebral foramen encroachment can produce sufficient pressure on neural contents to retard axoplasmic flow and the latency and amplitude of action potential transmission [58][59] Vertebral canal and IVF stenosis, with encroachment upon neural structures can occur as a result of vertebral subluxation with osseous degeneration and/or soft-tissue changes; such as disc thinning and bulging; ligament laxity, fibrosis, bucking; and joint capsule hypertrophy [60][61] In an examination of the degenerative effects of experimentally induced intervertebral hypomobility in the rat it was observed substantial increased zygapophysial articular cartilage erosion and hypertrophic spur formation associated with hypomobile vertebrae.[62]

2. Altered afferent input from spinal and paraspinal tissues is thought to attend subluxations and produce lasting and far-reaching effects via neuroplastic changes in the peripheral and central nervous systems.This widely held chiropractic theory posits that long-term changes in intervertebral mobility or alignment provides altered afferent input to the central nervous system, causing neuroplastic changes that impact biological function [56][63][64] This theory is generally extended to explain that spinal manipulation normalizes spine biomechanics, and as a consequence, normalizes afferent input to the central nervous system – resulting in normalized neurological function and improved health outcomes.

3. Dentate ligament mediated cord distortion has been proposed as a mechanism by which misaligned cervical vertebrae can directly stress sensitive brainstem and upper cervical cord structures, thereby disrupting critical neural processes. This theory is especially interesting to chiropractors that limit spinal manipulation to the upper cervical region.[65] Recently several investigators have reported a connective tissue bridge between the rectus capitus posterior minor (RCPm) and the spinal dura in the region of the posterior atlanto-occipital membrane [66][67] It has been proposed that this connective tissue bridge has two important physiological roles. It may prevent brain stem compression that could occur as a result of dural infolding during cervical flexion and extension and it may also stabilize the cranio-cervical region[67] In addition, a pathophysiological role has been proposed. It is thought that RCPm mediated tension on the pain sensitive posterior cerebro-spinal dura may be a primary mechanism for the etiology of cervicogenic headache.[68] Chiropractors are also interested in the reflex effects of spinal dysfunction with regards to the autonomic nervous system. recent neuroscience research supports a neurophysiologic rationale for the concept that aberrant stimulation of spinal or paraspinal structures may lead to segmentally organized reflex responses of the autonomic nervous system, which in turn may alter visceral function."[69]

Evidence-based practice guidelines

With growing mainstream acceptance of spinal manipulation in the 1980s[70]the 1990s resulted in a growing scholarly interest in chiropractic, which helped efforts to improve service quality and establish clinical guidelines. In the current advent of the evidence-based medicine era, chiropractic scholars have generated evidence-based systematic reviews and practice guidelines with respect to the management of acute/chronic low back pain,[71][72] thoracic pain, neck pain,[73] headache,[74] radiography,[75] [76] [77] and upper/lower extremity conditions.[78][79] tendinopathy[80] myofascial pain/trigger points,[81] and non-musculoskeletal conditions.[82]

Treatment

Manual and manipulative therapy

The medicinal use of spinal manipulation can be traced back over 3000 years to ancient Chinese writings. Hippocrates, the "father of medicine" used manipulative techniques[83] as did the ancient Egyptians and many other cultures. A modern re-emphasis on manipulative therapy occurred in the late 19th century in North America with the emergence of the osteopathic medicine and chiropractic medicine.[84] Spinal manipulation gained mainstream recognition during the 1980s.[85] Spinal manipulation/adjustment describes techniques where the hands are used to manipulate, massage, mobilize, adjust, stimulate, apply traction to, or otherwise influence the spine and related tissues.[86] It is the most common and primary intervention used in chiropractic care;[87] In North America, chiropractors perform over 90% of all manipulative treatments[88] with the balance provided by osteopathic medicine, physical therapy and naturopathic medicine. Manipulation under anesthesia or MUA is a specialized manipulative procedure that typically occurs in hospitals administered under general anesthesia.[89] Typically, it is performed on patients who have failed to respond to other forms of treatment.[90]There has been considerable debate on the safety of spinal manipulation, in particular with the cervical spine.[19] Although serious injuries and fatal consequences can occur and may be under-reported,[20] these are generally considered to be rare when spinal manipulation is employed skillfully and appropriately.[1]

Definitions

High-velocity low amplitude (HVLA) manipulative therapy is also known as 'adjustment' and Grade V mobilisation[91]

Categories

Manual and manipulative techniques can be categorized by different modes depending on therapeutic intent, indications, contraindications and safety.[92] Manual and mechanically-assisted articular manipulative procedures can include:

  • HVLA thrust manipulation
  • HVLA thrust manipulation with recoil
  • LVLA manipulation (mobilization)
  • Drop tables and terminal point manipulative thrust
  • Flexion-distraction and traction-type tables
  • Pelvic blocks
  • Instrument assisted manipulative devices

Manual non-articular manipulative procedures can include:

  • Reflex and muscle relaxation procedures
  • Muscle energy techniques
  • Myofascial ischemic compression procedures
  • Myofascial, and soft tissue manipulative techniques

Musculoskeletal disorders

The use of manual and manipulative therapies is a commonly used intervention used by manual medicine practitioners in the treatment of neuromusculoskeletal disorders. Spinal manipulation, in particular, is widely seen as a reasonable treatment option for biomechanical disorders of the spine, such as neck pain and low back pain[93] Manual therapies, including spinal manipulation, commonly used by chiropractors and other manual medicine practitioners are effective for the treatment of spinal pain, including low back pain, neck pain, some forms of headache and a number of extremity joint conditions such as shoulder and hip pain. Specifically, spinal manipulation/mobilization is effective in adults for: acute, subacute, and chronic low back pain; migraine and cervicogenic headache; cervicogenic dizziness; manipulation/mobilization is effective for several extremity joint conditions; and thoracic manipulation/mobilization is effective for acute/subacute neck pain[94]and might also be effective for the treatment of lumbar disc herniation with radiculopathy,[9][10] neck pain,[11] some forms of headache,[12][13] and some extremity joint conditions.[14][15]

Investigation of the effectiveness of spinal manipulation for specific musculoskeletal complaints include:

  • Low back pain. Most studies suggest spinal manipulation achieves equivalent or superior improvement in pain and function when compared with other commonly used interventions for short, intermediate, and long-term follow-up.[8] A 2008 review found strong evidence that SM is similar in effect to medical care with exercise.[95] A 2008 literature synthesis found good evidence supporting SM for low back pain regardless of duration.[96] The American College of Physicians and the American Pain Society jointly recommended that clinicians consider spinal manipulation for patients who do not improve with self care options.[97]
  • Radiculopathy. There is moderate quality evidence to support the use of spinal manipulation for the treatment of acute lumbar radiculopathy[9] and acute lumbar disc herniation with associated radiculopathy.[10] The evidence for chronic lumbar spine-related extremity symptoms and cervical spine-related extremity symptoms of any duration is low or very low and no evidence exists for the treatment of thoracic radiculopathy.[9]
  • Neck pain. Manual therapies, including spinal manipulation, has been found to be effective for mechanical neck pain.[94] [98][99][100][101] Thoracic spinal manipulation (TSM) has a therapeutic benefit to some patients with neck pain and therefore TSM or in combination with other interventions is a suitable intervention to use in the treatment of non-specific neck pain.[102]
  • Headache Spinal manipulation improves migraine and cervicogenic headaches but cautioned type, frequency, dosage, and duration of treatments should be based on guideline recommendations, clinical experience, and findings. Evidence for the use of spinal manipulation as an isolated intervention for patients with tension-type headache remains equivocal.[103] SM might be as effective as propranolol or topiramate in the prevention of migraine headaches,[12]
  • Cervicogenic dizziness There is moderate evidence to support the use of manual therapy for cervicogenic dizziness.[104]
  • Extremity conditions. Manual mobilizations to an exercise program for the treatment of knee osteoarthritis resulted in better pain relief then a supervised exercise program alone and suggested that manual therapists consider adding manual mobilisation to optimise supervised active exercise programs.[105] There is silver level evidence that manual therapy is more effective than exercise for the treatment of hip osteoarthritis, however this evidence could be considered to be inconclusive.[106] The addition of cervical spine mobilization to a treatment regimen for lateral epicondylosis (tennis elbow) result in significantly better pain relief and functional improvements in both the short and long-term.[107] There is a small amount of research into the efficacy of chiropractic treatment for upper limbs,[108] limited to low level evidence supporting chiropractic management of shoulder pain[15] and limited or fair evidence supporting chiropractic management of leg conditions.[14]

Non-musculoskeletal disorders

The evidence is inconclusive for cervical manipulation/mobilization alone for neck pain of any duration, and for manipulation/mobilization for mid back pain, sciatica, tension-type headache, coccydynia, temporomandibular joint disorders, fibromyalgia, premenstrual syndrome, and pneumonia in older adults. Spinal manipulation is not effective for asthma and dysmenorrhea when compared to sham manipulation, or for Stage 1 hypertension when added to an antihypertensive diet. In children, the evidence is inconclusive regarding the effectiveness for otitis media and enuresis, and it is not effective for infantile colic and asthma when compared to sham manipulation.Massage is effective in adults for chronic low back pain and chronic neck pain. The evidence is inconclusive for knee osteoarthritis, fibromyalgia, myofascial pain syndrome, migraine headache, and premenstrual syndrome. In children, the evidence is inconclusive for asthma and infantile colic.[94] [109] and no scientific data for idiopathic adolescent scoliosis.[110]

Safety

The safe application of spinal manipulation requires a thorough medical history, assessment, diagnosis and plan of management. Manipulative therapists, including chiropractors, must rule out contraindications to HVLA spinal manipulative techniques. Absolute contraindications refers to diagnoses and conditions that put the patient at risk to developing adverse events. For example, a diagnosis of rheumatoid arthritis and other conditions that structurally destabilizes joints, is an absolute contraindication of SMT to the upper cervical spine. Relative contraindications, such as osteoporosis are conditions where increased risk is acceptable in some situations and where mobilization and soft-tissue techniques would be treatments of choice. Most contraindication apply only to the manipulation of the affected region.[101]

Adverse events in spinal manipulation studies are believed to be under-reported [111] and appear to be more common following HVLA manipulation than mobilization.[112] Mild, frequent and temporary adverse events occur in SMT which include temporary increase in pain, tenderness and stiffness.[19] These events typically dissipates within 24–48 hours [113] Serious injuries and fatal consequences , especially to SM in the upper cervical region, can occur.[114] but are regarded as rare when spinal manipulation is employed skillfully and appropriately.[101]

There is considerable debate regarding the relationship of spinal manipulation to the upper cervical spine and stroke. Stroke is statistically associated with both general practitioner and chiropractic services in persons under 45 years of age suggesting that these associations are likely explained by preexisting conditions.[100][115][116] Weak to moderately strong evidence supports causation (as opposed to statistical association) between cervical manipulative therapy and vertebrobasilar artery stroke.[117] A 2012 systematic review determined that there is insufficient evidence to support a strong association or no association between cervical manipulation and stroke.[118]

Cost-effectiveness

Spinal manipulation is generally regarded as cost-effective treatment of musculoskeletal conditions when used alone or in combination with other treatment approaches.[119] Evidence supports the cost-effectiveness of using spinal manipulation for the treatment of sub-acute or chronic low back pain whereas the results for acute low back pain were inconsistent.[120]

Training

The entry criteria, structure, teaching methodology and nature of Chiropractic programs offered at Chiropractic schools vary considerably around the world. To help standardize and ensure quality of Chiropractic education, in 2005 the World Health Organization published guidelines for basic training and safety in Chiropractic. [121] In general, the World Health Organization lists three potential educational paths involving full‐time chiropractic education across the globe. This includes: 1 – 4 years of pre-requisite training in basic sciences at university level followed by a 4 year full‐time Doctorate program; DC. A 5 year integrated bachelor degree; BSc (Chiro). A 2 - 3 year Masters program following the completion of a bachelor degree; MSc (Chiro)[1] as well MTech (Chiro), a Masters of Technology in Chiropractic.[122]

Regardless of the model of education utilized, prospective chiropractors without relevant prior health care education or experience, must spend no less than 4200 student/teacher contact hours (or the equivalent) in four years of full‐time education. This includes a minimum of 1000 hours of supervised clinical training.[1] Health professionals with advanced clinical degrees, such as medical doctors, can meet the educational and clinical requirements to practice as a chiropractor in 2200 hours, which is most commonly done in countries where the profession is in its infancy.[121] Upon meeting all clinical and didactic requirements of chiropractic school, a degree in chiropractic medicine is granted. However, in order to legally practice, chiropractors, like all self regulated health care professionals, must be licensed.

All Chiropractic Examining Boards require candidates to complete a 12 month clinical internship to obtain licensure. Licensure is granted following successful completion of all state/provincial and national board exams so long as the chiropractor maintains malpractice insurance. Nonetheless, there still some variations in educational standards internationally depending on admission and graduation requirements. chiropractic medicine is regulated in North America by state/provincial statute. The regulatory boards are responsible for protecting the public, standards of practice, disciplinary issues, quality assurance and maintenance of competency.[123]

Ethics and medicolegal issues

Chiropractors, like other health care professionals, are self-regulated and have a fiduciary responsibility to protect the public and ensure competent, professional and ethical behaviour. Chiropractors have been noted to have increased instances of fraud, abuse and quackery compared to other health professions.[46] Internal criticism identified dubious practice techniques that promote high-volume treatments (which can increase dependency) and far-reaching and outlandish claims regarding the clinical significance of joint dysfunction/subluxation and its role in health and disease[124] As opposed to earlier in its history when founder D.D. Palmer claimed that spinal dysfunction/subluxation was the cause of all disease, modern chiropractic instituions and the international chiropractic educational accrediting agency (CCEI) has disavowed the the monocausal theory of joint dysfunction/subluxation.[6]

Regulation

Since its inception, chiropractic was controversial amongst the established medical orthodoxy. Chiropractors were jailed for "practicing medicine without a license" which the profession designed a legal and political defence against prosecution arguing that chiropractic was "separate and distinct from medicine", asserting that chiropractors "analyzed" rather than "diagnosed", and "adjusted" subluxations rather than "treated" disease.[34] In 1963 the American Medical Association formed a "Committee on Quackery" designed to "contain and eliminate" the chiropractic profession. In 1966, the AMA referred to chiropractic an "unscientific cult" and until 1980 and held that it was unethical for medical doctors to associate themselves with "unscientific practitioners".[125] The 1987, the AMA was found guilty of being engaged in an unlawful conspiracy in restraint of trade "to contain and eliminate the chiropractic profession." [34] In the 1980s, spinal manipulation gained mainstream recognition[126] and has spurred ongoing collaboration into research of manipulative therapies and models of delivery of chiropractic care for musculoskeletal conditions in the mainstream healthcare sector.[127][128][129]

Public health

Public health is becoming an increasingly important topic for chiropractors and what role they may play in the public health arena with recommendations suggesting the natural focus for the chiropractic profession is maintaining spinal and musculoskeletal health, good nutrition and an active lifestyle from childhood and throughout life, thereby promoting general health and freedom from chronic pain, disease and disability.[130] However, traditionally chiropractic has not endorsed mainstream public health measures such as mandatory vaccination and water fluoridation stating the patient should be able to freely choose for themselves.[131][131][132] [133]

Diagnostic imaging

Chiropractors employ diagnostic imaging techniques such as X-rays and CT scans to assist in the management of patient care. External and internal criticism regarding the frequency and inappropriate use of X-Rays, such as full spine radiographs, resulted in the development of evidence-based general practice guidelines in 2007 to improve patient safety by eliminating unnecessary exposure to radiation.[134][135]

Safety

There has been considerable debate on the safety of spinal manipulation, the core clinical act of chiropractors, in particular with the cervical spine.[19] Adverse events in SM studies are believed to be under-reported [111] and appear to be more common following HVLA manipulation than mobilization.[112] Although serious injuries and fatal consequences can occur and may be under-reported,[20] these are generally considered to be rare when spinal manipulation is employed skillfully and appropriately.[1] There is ongoing research investigating upper cervical manipulation and incidence of stroke.[118]

References

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