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List of Grey's Anatomy episodes

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The following is an episode list for the ABC drama Grey's Anatomy. The series began on March 27, 2005 airing in Boston Legal's timeslot to gain viewers from the hit series Desperate Housewives. The show quickly gained more viewers than Boston Legal, took over the time slot, and was picked up for a second season of 27 episodes (5 of which were originally slated to air with the first season) which began airing in September 2005.

As of January 14, 2010, a total of 113 episodes of Grey's Anatomy have been aired, plus four recap specials: "Straight to the Heart" (January 8, 2006, covering the first season and first half of the second season), "Under Pressure" (April 23, 2006, covering the second half of the second season), "Complications of the Heart" (September 21, 2006, covering the first two seasons), and "Every Moment Counts" (April 12, 2007, covering the first three seasons). Episodes 22 and 23 of Season 3 served as a backdoor pilot for the spin-off show Private Practice, featuring Kate Walsh as Dr. Addison Montgomery.

Series overview

Seasons Episodes Premiere Finale U.S. ratings
(rank)
DVD Release
Region 1 Discs Region 2 Discs
1 9 March 27, 2005 May 22, 2005 18.46 mil.[1]
(9th place)
February 14, 2006 2 April 5, 2006 3
2 27 September 25, 2005 May 15, 2006 19.44 mil.[2]
(5th place)
September 12, 2006 6 January 10, 2007 7
3 25 September 21, 2006 May 17, 2007 19.22 mil.[3]
(8th place)
September 11, 2007 7 October 31, 2007 7
4 17 September 27, 2007 May 22, 2008 15.92 mil.[4]
(10th place)
September 9, 2008 5 November 26, 2008 5
5 24 September 25, 2008 May 14, 2009 14.52 mil.[5]
(12th place)
September 15, 2009 7 November 11, 2009 7
6 24 September 24, 2009 May 2010 TBA - 7 - 7

Season 1: 2005

Episode Title Written by Directed by American viewers in millions Original airdate
1-01 (1)"A Hard Day's Night"[6]Shonda RhimesPeter Horton16.25[7]March 27, 2005 (2005-03-27)
Meredith Grey (Ellen Pompeo) enrolls in the surgical residency program at Seattle Grace Hospital, where she will spend the next 7 years. Hours into the program, Meredith discovers that a stranger she had a one-night-stand with is her new boss, Derek Shepherd (Patrick Dempsey). Preston Burke (Isaiah Washington), a cardiothoracic surgeon in the hospital begins to question his abilities, and decides to choose George (T.R. Knight) to perform the first operation, which earns him the nickname 007.
1-02 (2)"The First Cut Is the Deepest"[8]Shonda RhimesPeter Horton17.71[9]April 3, 2005 (2005-04-03)
Meredith looks for roommates to share her mother's house with, while tending to a rape victim and discovering an ailment with a newborn baby. Izzie (Katherine Heigl) helps out a Chinese woman whose daughter is in need, and Shepherd and Burke quarrel over the Chief of Surgery position.
1-03 (3)"Winning a Battle, Losing the War"[10]Shonda RhimesTony Goldwyn17.99[11]April 10, 2005 (2005-04-10)
Competition between the interns ensues after an annual unauthorized bike race causes many injuries. Izzie has trouble locating the family of a near brain-dead man, and Cristina (Sandra Oh) is excited when the patient's family agrees to harvest his organs if he dies, leading Bailey (Chandra Wilson) to lecture her on bedside manner. A patient who is a friend of Dr. Webber flirts with George.
1-04 (4)"No Man's Land"[12]James D. ParriottAdam Davidson19.18[13]April 17, 2005 (2005-04-17)
When a retired nurse at Seattle Grace is admitted, Cristina takes on her case and befriends her. A patient who recognizes Izzie from a modeling photo does not want her to treat him. Meredith and Shepherd treat a construction worker who surprisingly survived his injuries, but have bad news for his wife about his future. Alex (Justin Chambers) humiliates Izzie in front of everyone.
1-05 (5)"Shake Your Groove Thing"[14]Ann HamiltonJohn David Coles17.90[15]April 24, 2005 (2005-04-24)
Izzie plans a party for her old boyfriend, while Meredith believes she may be in trouble when something goes wrong during a procedure. At the party, Bailey spots Shepherd and Meredith together. Cristina and Burke have sex in an on-call room.
1-06 (6)"If Tomorrow Never Comes"[16]Krista VernoffScott Brazil17.88[17]May 1, 2005 (2005-05-01)
When Shepherd picks Meredith to assist in surgery on a patient with Parkinson's disease, Bailey thinks he is showing favoritism and is tough on Meredith. Alex befriends a patient who has a very large tumor, but when he talks about her behind her back, she requests he be removed from her case.
1-07 (7)"The Self-Destruct Button"[18]Kip KoenigDarnell Martin18.86[19]May 8, 2005 (2005-05-08)
Derek spends the night at Meredith's, which they try to keep secret from her other roommates. George suspects an anesthesiologist of drinking before major surgeries but is scolded when he does speak up. Alex treats a man who enjoys being in pain, and Cristina catches the flu.
1-08 (8)"Save Me"[20]Mimi SchmirSarah Pia Anderson18.33[21]May 15, 2005 (2005-05-15)
Alex treats a teenage Orthodox Jew who refuses surgery when she learns the treatment goes against her beliefs. Cristina has trouble relating to a pregnant woman who has terminal cancer and refuses to abort the baby, turning to Meredith for advice. Izzie is mesmerized by a patient who has psychic abilities, and is diagnosed with AVM.
1-09 (9)"Who's Zoomin' Who?"[22]Gabrielle Stanton and Harry Werksman, Jr.Wendey Stanzler22.22[23]May 22, 2005 (2005-05-22)
Meredith is shocked when someone from Derek's past arrives at Seattle Grace. When a number of interns, including George, are diagnosed with STDs, Dr. Webber calls an emergency meeting. Izzie and Cristina want to perform an unauthorized autopsy against the family's wishes.

Season 2: 2005–2006

Episode Title Written by Directed by Viewers (m) Premiere
2-01 (10)"Raindrops Keep Falling On My Head"[24]Stacy McKeePeter Horton18.98[25]September 25, 2005 (2005-09-25)
Joe the bartender finds himself in the need of a very expensive standstill surgery that there is no way he'll be able to afford. Much to Meredith's discomfort, Addison requests her as her intern for the day. Still recovering from surgery, Dr. Webber asks George to be his "eyes and ears", but George finds it difficult to pass on any information. Cristina tells Meredith that she is pregnant without revealing the father. When Preston breaks off their relationship, she decides not to tell him either. Izzie and Alex's personal bond grows closer as he shows a more emotional side of himself.
2-02 (11)"Enough is Enough (No More Tears)"[26]James D. ParriottPeter Horton17.57[27]October 2, 2005 (2005-10-02)
Adele cuts her vacation short to come and care for Dr. Webber who is still recovering from surgery. Cristina and Meredith both express a great deal of bitterness toward their past doctoral flames. After having worked with nurse Olivia all day, George admits that he likes someone else. Alex and Izzie treat the victims from a car crash where the father needs a liver transplant, but his son doesn't want to donate because of the way his father abuses his mother. Bailey treats a man who has swallowed the heads of ten Judy dolls.
2-03 (12)"Make Me Lose Control"[28]Krista VernoffAdam Davidson18.12[29]October 9, 2005 (2005-10-09)
Ellis Grey is brought into the hospital for possible diverticulitis, and her Alzheimer's condition becomes known to everyone. George is assigned to her case, but she refuses him to treat her, thinking he's her ex-husband. Alex and Meredith treat a young patient with extreme blushing. Izzie stands up for her and Alex's blossoming friendship to the others. To Preston's shock, Cristina collapses in the O.R. and Addison has to remove her Fallopian tube, causing her baby to be aborted. Meredith tells Derek that hating him is exhausting and that she doesn't want to do it anymore.
2-04 (13)"Deny, Deny, Deny"[30]Zoanne ClackWendey Stanzler18.28[31]October 16, 2005 (2005-10-16)
Cristina is still recovering from her surgery while receiving a visit from her mother. Not wanting to rest in bed, she uninvited diagnoses Burke and Izzie's patient with Münchhausen's syndrome. Eager to seem fine, Cristina have refused to mourn all day, but in the end, she breaks down. Addison gives Derek divorce papers to sign, but he can't make up his mind. Alex asks Izzie on a date, but finding out that he hasn't passed an exam makes him unable to make the most of it. Bailey treats a longtime patient with cystic fibrosis to whom she's emotionally attached.
2-05 (14)"Bring the Pain"[32]Shonda RhimesMark Tinker18.00[33]October 23, 2005 (2005-10-23)
Meredith and Derek have to use more than medicine when a young Asian woman's traditionalist, religious father forbids her to have a life-saving operation unless a shaman is called upon to "retrieve her souls". Meanwhile, George and Alex are forced to perform surgery in a trapped elevator in an attempt to save a patient’s life in which George shows his potential while Alex shuns the challenge, and it is decision time for Derek and the two women in his life.
2-06 (15)"Into You Like a Train"[34]Krista VernoffJeff Melman16.67[35]October 30, 2005 (2005-10-30)
As Meredith nervously awaits a final decision from Derek, her fear is interrupted when a train crash brings several seriously injured patients to the hospital. The doctors must make a tough decision in order to save at least one of them. Meredith understands that Derek has chosen Addison, and is crushed. Alex fails to notice a woman bleeding internally and she eventually dies from her injuries. As Addison and Izzie work with two pregnant women, Addison sees great potential in Izzie, who must decide whether her loyalty as Meredith’s friend outweighs professional gain.
2-07 (16)"Something to Talk About"[36]Stacy McKeeAdam Davidson18.13[37]November 6, 2005 (2005-11-06)
Cristina, Izzie and Meredith aggressively pursue the case of Shane, a male patient who seems to have a hysterical pregnancy, which fascinates them and the entire medical staff, and also angers Meredith because everyone in the hospital is not respecting the privacy of the patients. In a parallel situation, many hospital workers whisper continuously about Derek and Meredith and give them little privacy as well. A sheltered young patient inspires Alex to better express his feelings for Izzie. The episode ends with Alex arriving at the bar, pulling Izzie backwards and kissing her.
2-08 (17)"Let It Be"[38]Mimi SchmirLesli Linka Glatter19.74[39]November 13, 2005 (2005-11-13)
Derek and Addison Shepherd's professional relationship is challenged when their friends from Manhattan come to Seattle Grace seeking a radical, preemptive operation to avoid breast and ovarian cancer. Meanwhile, George can’t understand why a patient who fell five stories doesn’t seem happy to have survived and an elderly gentleman makes a difficult decision upon learning that his wife has only a few months to live. Cristina and Burke try to have a "normal" date, and Dr. Webber is disappointed by Bailey's fellowship decision -- until he learns her reasons: that she is pregnant.
2-09 (18)"Thanks for the Memories"[40]Shonda RhimesMichael Dinner20.33[41]November 20, 2005 (2005-11-20)
The Thanksgiving holiday is more difficult for the interns and residents than any of them is willing to admit, as Izzie plans a big dinner. George endures the family tradition of hunting turkeys with his father and brothers. Having sneaked off to the hospital instead of helping Izzie out, Meredith treats a patient who's been in a vegetative state for 16 years. Burke helps Izzie to prepare the Thanksgiving meal. Just as Izzie is about to give up on anyone showing up for dinner, Alex, George and Cristina come back, while Meredith celebrates with a one-night-stand at Joe's bar.
2-10 (19)"Much too Much"[42]Gabrielle Stanton and Harry Werksman, Jr.Wendey Stanzler19.59[43]November 27, 2005 (2005-11-27)
Meredith is mortified when her one night stand shows up at the hospital suffering from priapism and needing medical attention. Izzie, Addison and Derek are assigned to a case where a woman carrying quintuplets is overwhelmed by numerous medical issues as she navigates her high-risk pregnancy. Alex’s shortcomings frustrate Izzie, especially when she catches Alex and Olivia having sex. On the other hand, Alex again shows his incompetence in treating one of his patients by administering the wrong dosage. Cristina reluctantly shows Preston where she lives.
2-11 (20)"Owner of a Lonely Heart"[44]Mark WildingDan Minahan20.59[45]December 4, 2005 (2005-12-04)
Cristina has little sympathy for Constance Ferguson, a prison inmate who jeopardizes her health just to get out of solitary confinement. The interns all keep careful watch on the family of premature quintuplets with a variety of serious health challenges. Izzie's anger at Alex reaches boiling point. Addison decides to teach Izzie a very painful lesson which she too once received from the chief, wanting Izzie to know the consequences of being too attached to her patients.
2-12 (21)"Grandma Got Run Over By a Reindeer"[46]Krista VernoffPeter Horton15.70[47]December 11, 2005 (2005-12-11)
A young boy needs a heart transplant but doesn't seem to want it, and an argument over his treatment exposes major philosophical differences between Burke and Cristina. Meanwhile, when the interns rally to help Alex prepare to re-take his exam, Izzie feels betrayed and Meredith has to remind her of the true spirit of the Christmas holiday. Derek performs brain surgery on the patriarch of a mixed Jewish/Christian family who discuss celebrating Chrismukkah, but isn't in a festive mood despite a reconciliation with his wife.
2-13 (22)"Begin the Begin"[48]Kip KoenigJessica Yu18.97[49]January 15, 2006 (2006-01-15)
Dr. Webber enforces an 80 hour per week maximum rule for the interns. Derek wants to enroll Ellis in a experimental treatment for Alzheimer's, but Meredith doesn't want his help and Derek needs Dr. Webber to intervene. Izzie seems to be getting over Alex when she shares an undeniable chemistry with Denny Duquette, a patient awaiting a heart transplant. Bailey goes to retrieve Denny's heart, taking Cristina along for the ride. Meanwhile George and Addison treat Bex, a young teen hermaphrodite.
2-14 (23)"Tell Me Sweet Little Lies"[50]Tony Phelan & Joan RaterAdam Davidson21.04[51]January 22, 2006 (2006-01-22)
The truth is in short supply as Meredith and Cristina lie to each other about the status of their relationships. Cristina is angry with Derek since he has Meredith calling him McDreamy again. Cristina 'kinda' moves in with Burke. George is given the unpleasant task of discharging an elderly patient who refuses to leave the hospital despite no longer being sick. A competitive eater is presented with a tear in the lining of her esophagus. Alex is so nervous about the results of his exam that he eventually asks Izzie to open them for him (he passes).
2-15 (24)"Break on Through"[52]Zoanne ClackDavid Paymer18.44[53]January 29, 2006 (2006-01-29)
Amidst a strike by the nurses, Meredith revives an elderly patient without knowing she's not supposed to. As the patient dies with her friends at her side, Meredith realizes she doesn't want her mother to die alone, and allows the chief to continue visit her, something she initially was upset with. Izzie treats a pregnant teenager with whom she has much in common, and her interfering upsets the patient's mother. Cristina is irritated with the perky new resident, Sydney, and asks for Burke's intervention when Sydney attempts a risky procedure to save a woman's infected leg from amputation.
2-16 (25)"It's the End of the World (1)"[54]Shonda RhimesPeter Horton37.88[55]February 5, 2006 (2006-02-05)
Meredith has a feeling and George and Izzie have to call in Cristina to get her out of bed. A paramedic brings in a man with live ammunition in his chest; her hand is the only thing preventing an explosion. Bailey goes into labor and Derek and Cristina perform surgery on Bailey's husband who crashed the car on his way in. Izzie initiates things with Alex. When the anesthesiologist leaves the paramedic alone in the O.R., she panics and pulls her hand out of the patient - but Meredith takes her place.
2-17 (26)"(As We Know It)"[56]Shonda RhimesPeter Horton25.42[57]February 12, 2006 (2006-02-12)
Without her husband by her side, Bailey refuses to have the baby and George works with Addison to convince her to. Dr. Webber's stress causes an anxiety attack that brings Adele to the hospital. Meredith removes the explosive from the patient, but it explodes and kills Dylan. Preston and Derek overcome their initial rivalry and call each other by their first names. Cristina says "I love you too" to a sleeping Preston. Derek comes visiting Meredith after she nearly dies and Meredith tells him that she can't remember their last kiss.
2-18 (27)"Yesterday"[58]Krista Vernoff (teleplay)
Mimi Schmir (story)
Rob Corn24.36[59]February 19, 2006 (2006-02-19)
Dr. Mark Sloan arrives in Seattle to try to convince Addison to continue their relationship, and is greeted with a punch from Derek, just for flirting with Meredith. Dr. Webber allows Sloan to assist Derek in a risky surgery to fix a teenage patient with facial tumors. Preston learns that Cristina still leases her apartment. Izzie treats a patient with spontaneous orgasms. Meredith goes to see her father for the first time in twenty years and is left unsatisfied with his answers about the past. George finally tells Meredith how he feels about her.
2-19 (28)"What Have I Done to Deserve This?"[60]Stacy McKeeWendey Stanzler24.76[61]February 26, 2006 (2006-02-26)
Following their sexual encounter, Meredith and George avoid each other at work, and George ends up falling down a stairwell and dislocating his shoulder. Frequent heart patient Denny is readmitted and grows closer to Izzie, causing Alex to be jealous. Although Bailey is on maternity leave, Addison asks for her treatment after her exposure and allergic reaction to poison oak. George moves in with Burke and Cristina and catches the eye of ortho resident Dr. Callie Torres.
2-20 (29)"Band-Aid Covers the Bullet Hole"[62]Gabrielle Stanton & Harry Werksman, Jr.Julie Anne Robinson22.51[63]March 12, 2006 (2006-03-12)
After Dr. Bailey is called into surgery, Cristina is forced to watch baby Tucker for the remainder of the day. Meanwhile, George and Meredith are still on the outs as she confides in Derek with her problem. Izzie continues to warm up to Denny who is having problems breathing. George and Callie further their flirtations over a teenaged patient who decides to chop off his own finger after Callie refuses to do it for him. Burke shows a preference for living with George over Cristina, and Addison gets a long-awaited admission from Derek that shows some hope for their marriage after all.
2-21 (30)"Superstition"[64]James D. ParriottTricia Brock21.13[65]March 19, 2006 (2006-03-19)
When a series of deaths occur at Seattle Grace, the uncanny events bring out the doctors' superstitious sides. Four deaths in the morning implies that three more deaths are due for the day. This makes Izzie nervous about Denny's surgery, and a jealous Alex informs Denny of the likelihood of his death, prompting Izzie to completely end their relationship. Meanwhile, Derek and Addison discuss making a more permanent living arrangement, and Dr. Webber treats a former sponsor from his alcoholic's anonymous group. Izzie kisses Denny after he survives his surgery.
2-22 (31)"The Name of the Game"[66]Blythe RobeSeith Mann22.35[67]April 2, 2006 (2006-04-02)
Bailey worries Dr. Webber is mommy-tracking her and becomes Derek's intern for the day. George begins a relationship with Callie and finds her living in the hospital. Meredith takes up knitting -- and a vow of celibacy. Cristina competes with the Chief during classroom exercises. Burke tries to teach Alex a lesson about bedside manners, but it's a lesson that falls on deaf ears. Izzie tries to get George to move back into the house. George discovers that Addison's patient is Meredith's half-sister. Meredith meets Doc's vet, and takes a shine to him.
2-23 (32)"Blues for Sister Someone"[68]Elizabeth KlaviterJeff Melman20.76[69]April 30, 2006 (2006-04-30)
Izzie grills George about the personal details of his life. Addison and Alex treat a Catholic woman who is pregnant with her seventh child and wants Addison to perform a tubal ligation during the caesarean section. Burke performs surgery on his musical hero who wants a pacemaker removed as it has ruined his ability to play the violin. Meredith learns from Denny that life is too short to follow the rules, and decides to abandon her knitting and accept a date with Doc's vet. George moves back in with Izzie and Meredith. Derek finally agrees to have hot sex with Addison.
2-24 (33)"Damage Control"[70]Mimi SchmirTony Goldwyn21.99[71]May 7, 2006 (2006-05-07)
A family is involved in a car accident caused by a surgical intern from another hospital. The young pregnant wife has massive injuries and eventually dies, though Alex performs a Caesarean section to save the baby. Derek is angry at Meredith after he sees her at the vet's. Burke is angry at Cristina after she fell asleep during sex the previous night. George does not stand up for Callie to his roommates and Denny is becoming angry at being stuck in bed with no end in sight.
2-25 (34)"17 Seconds"[72]Mark WildingDan Minahan22.60[73]May 14, 2006 (2006-05-14)
Gunshot victims from a nearby restaurant crowd Seattle Grace and the doctors are fully occupied. Knowing that Derek is mad at Meredith for dating Finn, Addison yells at him in the hallways, not realizing everyone can hear. Meredith asks Callie for advice on bone cancer in dogs. Burke is still angry at Cristina and chooses Alex over her to go with him to retrieve a heart for Denny. When Izzie finds out that Denny is about to not get the heart, she takes the matter in her own hands. As Burke races back to SGH to keep Izzie from doing something drastic, both Burke and Denny wind up in critical situations.
2-26 (35)"Deterioration of the Fight or Flight Response"[74]Tony Phelan and Joan RaterRob Corn22.50[75]May 15, 2006 (2006-05-15)
The interns help Izzie keep Denny alive after she's cut his LVAD wire. Derek must perform surgery on Burke's shoulder and risk doing irreparable damage to the nerves. Cristina freezes in the O.R. during Burke's surgery. The chief discovers his niece's cancer has returned. Alex fights for Denny's heart at Mercy West, eventually offering Dr. Hahn the chance to scrub in at the surgery as Burke has been shot. Before surgery, Denny asks Izzie to marry him. However, after the heart has been inserted, it does not beat and back in Derek's OR, Burke still cannot move his fingers.
2-27 (36)"Losing My Religion (3)"[76]Shonda RhimesMark Tinker22.50[75]May 15, 2006 (2006-05-15)
The interns are pulled into Dr. Webber's office for interrogation regarding the LVAD wire situation. None of them reveal the truth, protecting Izzie. Dr. Webber tells them all that they're off surgery, and they are to give his niece a prom. Burke finds a tremor in his right hand. Meredith and Derek make the decision to put Doc to sleep. Izzie accepts Denny's marriage proposal. During the prom, Derek and Meredith reunite in an exam room. The interns find Izzie lying in bed clinging to Denny, whose heart has stopped. Izzie leaves Seattle Grace, and on her way out confesses to Dr. Webber that she cut the LVAD wire and that she quits the program. Meredith remains torn on who she should follow: Derek or Finn.

Season 3: 2006-2007

Episode Title Written by Directed by Viewers (m) Premiere
3-01 (37)"Time Has Come Today"[77]Shonda RhimesDan Minahan25.41September 21, 2006 (2006-09-21)
The doctors of Seattle Grace help Izzie cope with the loss of her fiancé, Denny, and her decision to quit the internship program. Meredith must decide what the future holds after her hospital liaison with Derek. The Chief is confronted by his wife, Adele (Loretta Devine), after spending the night in his office, and George seeks relationship advice from a surprising source.
3-02 (38)"I Am a Tree"[78]Krista VernoffJeff Melman23.31September 28, 2006 (2006-09-28)
Cristina meets Burke's parents, in the most awkward of circumstances, Izzie begins baking to comfort herself, Addison takes a break from her hospital duties and gets drunk, Richard discovers Callie living in the hospital, and a surgical patient lives what may be her last day to the fullest.
3-03 (39)"Sometimes a Fantasy"[79]Debora CahnAdam Arkin22.46October 5, 2006 (2006-10-05)
Cristina tries to help Preston cope with his hand tremor, Izzie attempts to return to the hospital for the first time since she left the program, Alex deals with a patient who has a long history of injuries and believes she is a super hero, and George and Callie’s relationship moves forward.
3-04 (40)"What I Am"[80]Allan HeinbergDan Lerner22.82October 12, 2006 (2006-10-12)
Addison doubts her abilities as a doctor, Cristina pushes Burke's rehabilitation and Izzie receives the surprise of her life.
3-05 (41)"Oh, the Guilt"[81]Zoanne Clack, Tony Phelan and Joan RaterJeff Melman21.93October 19, 2006 (2006-10-19)
Bailey treats a young mother battling breast cancer, Derek learns more about Mark and Addison's relationship, the interns defend a resident's competence at a hospital staff meeting, and Meredith and Addison examine a couple who find themselves in a rather awkward position.
3-06 (42)"Let the Angels Commit"[82]Stacy McKeeJessica Yu20.96November 2, 2006 (2006-11-02)
Cristina scrubs in on the rare "humpty dumpty" procedure, much to the envy of her fellow doctors, Alex questions his future medical specialty, George and Addison work with a pregnant woman with an unusual dilemma, and Derek receives a surprise visit from his sister.
3-07 (43)"Where the Boys Are"[83]Mark WildingDan Minahan20.57November 9, 2006 (2006-11-09)
The men of Seattle Grace go on a camping trip together, Addison and Callie must team up to work on a patient, Meredith assist Sloan with a procedure unlike any she has experienced, and, suspicious of her recent actions at the hospital, Bailey confronts Cristina.
3-08 (44)"Staring at the Sun"[84]Gabrielle Stanton and Harry Werksman, Jr.Jeff Melman20.96November 16, 2006 (2006-11-16)
The O'Malley Family visits George at the hospital, Meredith is determined to have a more positive outlook on life, Derek and Addison strive for a civil relationship, and Richard endeavors to reunite with his wife, Adele.
3-09 (45)"From a Whisper to a Scream"[85]Kip KoenigJulie Anne Robinson18.46November 23, 2006 (2006-11-23)
A traumatic car accident fills the ER, Cristina has a crisis of conscience about her deceptive teamwork with Burke, and Izzie pushes the boundaries of her probation.
3-10 (46)"Don't Stand So Close to Me"[86]Carolina PaizSeith Mann24.27November 30, 2006 (2006-11-30)
Recent events strain Burke and Cristina's relationship, Meredith's half-sister, Molly, is admitted to the hospital, and Derek and Mark must work together when two close-knit brothers seek medical help.
3-11 (47)"Six Days, Part 1"[87]Krista VernoffGreg YaitanesTBAJanuary 11, 2007 (2007-01-11)
Part one of a two-part episode. After a successful operation on his heart, George's father undergoes surgery for his cancer, Thatcher Grey visits Seattle Grace in order to see his new granddaughter, and Meredith discovers that Derek has trouble sleeping soundly.
3-12 (48)"Six Days, Part 2"[88]Krista VernoffGreg Yaitanes21.89January 18, 2007 (2007-01-18)
Part two of a two-part episode. George and his family must struggle with a difficult decision regarding Harold who is on life support. Meredith learns she shares something in common with her father. Addison regrets an event from her past. Izzie is barred from Heather's surgery after Bailey finds out she paid for the operation.
3-13 (49)"Great Expectations"[89]Eric BuchmanMichael Grossman21.40January 25, 2007 (2007-01-25)
After the Chief announces his retirement, rumors begin to circulate on his departure and successor. Dr. Bailey is ambitious to create a free medical clinic. Two people at the hospital receive an unexpected proposal.
3-14 (50)"Wishin' and Hopin'"[90]Tony Phelan & Joan RaterJulie Anne Robinson23.92February 1, 2007 (2007-02-01)
The race for the Chief's position is on, as the doctors compete for Richard's affections, a surgical patient endangers the lives of those around her, and Meredith's Alzheimer's-stricken mother, Ellis, experiences a change in her medical condition.
3-15 (51)"Walk On Water"[91]Shonda RhimesRob CornTBAFebruary 8, 2007 (2007-02-08)
Part one of a three-part story arc. A mass trauma situation challenges the interns in many different ways. Richard begins a transition while going through a life change, while Cristina struggles to tell Meredith and the others about becoming engaged to Burke.
3-16 (52)"Drowning On Dry Land"[92]Shonda RhimesRob Corn25.59February 15, 2007 (2007-02-15)
Part two of a three-part story arc. Meredith is still under water which no one realizes until Derek finds her coat. Izzie drills holes into a trauma patient's head who is experiencing seizures. George continues to look for a patient's lost son after providing her with false optimism. Alex finds no hope in searching for the pregnant Jane Doe's family as she undergoes surgery.
3-17 (53)"Some Kind of Miracle"[93]Shonda Rhimes and Marti NoxonAdam Arkin27.28February 22, 2007 (2007-02-22)
Part three of a three-part story arc. The interns of Seattle Grace take vigil outside Meredith's hospital room as Bailey and the Chief struggle to revive her. Meanwhile, Meredith is in limbo where she meets up with Denny, Dylan and many other familiar deceased patients from the past. Cristina remedies her grief for Meredith by shopping and Alex continues to bond with the pregnant Jane Doe who remains unclaimed. Ellis Grey goes into cardiac arrest.
3-18 (54)"Scars and Souvenirs"[94]Debora CahnJames Frawley22.38March 15, 2007 (2007-03-15)
The race for chief heats up after a new competitor enters the fray, tensions escalate between Izzie and George, and Callie must reveal a big secret. Meanwhile, Derek treats a patient near and dear to him, while Alex continues his work with Jane Doe.
3-19 (55)"My Favorite Mistake"[95]Chris Van DusenTamra Davis21.89March 22, 2007 (2007-03-22)
George meets his new father-in-law (Hector Elizondo) (and is in no condition to make a good impression), Alex helps Jane Doe determine how the world will see her from now on, the hospital board begins interviewing the candidates for the Chief's position, and Izzie wrestles with a startling revelation.
3-20 (56)"Time After Time"[96]Stacy McKeeChristopher Misiano20.91April 19, 2007 (2007-04-19)
When Izzie's daughter is brought to the hospital for leukemia treatment, Izzie is asked to donate her bone marrow in support. Derek finds that Meredith stands in his way of becoming chief. Marlowe continues to intrude on Burke and Cristina's lives with an impending surgery Burke will perform. Meredith becomes closer to her stepmother (Mare Winningham). Parents claiming to be Ava's come in to identify her but learn she is not theirs.
3-21 (57)"Desire"[97]Mark WildingTom Verica19.75April 26, 2007 (2007-04-26)
As the interns of Seattle Grace cram for their upcoming exam, the attendings vie for the Chief's position by tending to the chairman of the hospital board (Mitch Pileggi) after he is admitted as a patient. Meanwhile, Burke struggles to involve Cristina in the wedding planning, things heat up between Addison and Alex, and Derek questions his relationship with Meredith.
3-22 (58)"The Other Side of This Life, Part 1"[98]Shonda RhimesMichael Grossman20.97May 3, 2007 (2007-05-03)
Part one of a two-hour episode. After things become too complicated in Seattle, Addison travels to Los Angeles to reunite with old friends from medical school. Meanwhile, Derek must perform emergency surgery on Ava/Jane (Elizabeth Reaser) Doe and Cristina plans her wedding with both her mother and Burke's. This double episode is a backdoor pilot for Private Practice.
3-23 (59)"The Other Side of This Life, Part 2"[99]Shonda RhimesMichael Grossman20.97May 3, 2007 (2007-05-03)
Part two of a two-hour episode. After things become too complicated in Seattle, Addison travels to Los Angeles to reunite with old friends from medical school. Meanwhile, Derek must perform emergency surgery on Ava/Jane Doe and Cristina plans her wedding with both her mother and Burke's. This double episode is a backdoor pilot for Private Practice.
3-24 (60)"Testing 1-2-3"[100]Allan HeinbergChristopher Misiano19.07May 10, 2007 (2007-05-10)
The interns take the biggest test of their careers, their first-year medical exams, as the residents attend to three injured mountain climbers. Meanwhile Callie’s suspicions of George and Izzie grow, and Cristina struggles to write her wedding vows.
3-25 (61)"Didn't We Almost Have It All?"[101]Tony Phelan and Joan RaterRob Corn21.53May 17, 2007 (2007-05-17)
Cristina and Burke’s wedding day arrives. Along with the interns’ first exam results, a successor to the Chief is named. Callie and George make a big decision about their relationship. Meredith and Derek call their relationship "Over?".

Season 4: 2007–2008

Episode Title Written by Directed by Premiere Viewers (m)
4-01 (62)"A Change Is Gonna Come"[102]Shonda RhimesRob CornSeptember 27, 2007 (2007-09-27)20.48
Having just returned from her honeymoon with Meredith, Cristina searches for Burke, but he is nowhere to be found. Meredith, Cristina, Izzie and Alex spend their first day as residents with their own groups of interns. Among the interns are George, repeating his intern year after failing his exams, is Lexie Grey, Meredith's half-sister whom she has never met. Now that Derek's relationship with Meredith has reached an emotional impasse, he looks to his fellow doctors for friendship; Bailey wrestles with her place within the hospital now that her former interns report to new Chief Resident Callie; and Richard resumes his position as Chief of Surgery.
4-02 (63)"Love/Addiction"[103]Debora CahnJames FrawleyOctober 4, 2007 (2007-10-04)18.13
The residents and interns treat the victims of a massive explosion at an apartment building, while Alex investigates the cause of the accident, Mama Burke (Diahann Carroll) returns to collect her son's things just as Cristina trades her wedding presents in exchange for surgeries, Lexie tries to have a heart-to-heart with an unwilling Meredith, and while Callie is overwhelmed with her duties as Chief Resident, Bailey searches for an outlet for her pent-up leadership skills.
4-03 (64)"Let the Truth Sting"[104]Mark WildingDan MinahanOctober 11, 2007 (2007-10-11)18.65
Meredith reluctantly helps Lexie with her first surgical procedure, while Lexie helps keep George's "repeater" status a secret from their fellow interns.
4-04 (65)"The Heart of the Matter"[105]Allan HeinbergRandy ZiskOctober 18, 2007 (2007-10-18)17.67
Izzie confides in Alex about George and the reaction is not what she expected, the Chief's niece returns to the hospital where she once had her prom, and Derek teaches Cristina how to be a better resident to her interns.
4-05 (66)"Haunt You Every Day"[106]Krista VernoffBethany RooneyOctober 25, 2007 (2007-10-25)17.97
Halloween is full of surprises for the Seattle Grace doctors when Ava makes an unexpected visit to see Alex, Meredith thinks her deceased mother is haunting her, and Callie reveals George and Izzie's affair to their fellow doctors.
4-06 (67)"Kung Fu Fighting"[107]Stacy McKeeTom VericaNovember 1, 2007 (2007-11-01)18.76
With his marriage in trouble, the Chief turns to his fellow male surgeons for a "gentlemen's evening," Cristina and Izzie heatedly compete for the same surgery, and the doctors treat two injured finalists from a promotional wedding competition.
4-07 (68)"Physical Attraction, Chemical Reaction"[108]Tony Phelan and Joan RaterJeff MelmanNovember 8, 2007 (2007-11-08)19.31
George and Izzie's romantic chemistry is put to the test, Mark develops a crush on a fellow surgeon, and Callie's role as Chief Resident is in jeopardy.
4-08 (69)"Forever Young"[109]Mark WildingRob CornNovember 15, 2007 (2007-11-15)19.61
A schoolbus crash floods Seattle Grace with teenagers, Derek goes out on a date with a fellow doctor, and Meredith sees her father for the first time since her stepmother's death.
4-09 (70)"Crash Into Me, Part 1"[110]Shonda Rhimes and Krista VernoffMichael Grossman and Jessica YuNovember 22, 2007 (2007-11-22)14.11
Part one of a two-part episode. An ambulance crash endangers the lives of the paramedics involved, as Meredith and the Chief work on-site to save them, Bailey treats a patient who refuses her help, and Ava returns for Alex and meets his other girlfriend in the process.
4-10 (71)"Crash Into Me, Part 2"[111]Shonda Rhimes and Krista VernoffJessica YuDecember 6, 2007 (2007-12-06)17.78
Part two of a two-part episode. Meredith furiously works to save the life of a paramedic trapped inside an ambulance, as her sister, Lexie, holds the life of a patient (Seth Green) in her hands, and Derek must rely on the help of a nurse to save a patient's life.
4-11 (72)"Lay Your Hands On Me"[112]Allan HeinbergJohn TerleskyJanuary 10, 2008 (2008-01-10)17.68
Bailey's family faces a medical trauma just as her marriage is falling apart, George receives a very unexpected visit from his mother, and a faith healer wishes to forgo traditional surgery.
4-12 (73)"Where the Wild Things Are"[113]Zoanne ClackRob CornApril 24, 2008 (2008-04-24)16.02
Six weeks have passed since Derek started dating Rose, and the new residents are competing in a surgical contest. George and Lexie move into their new apartment and Lexie begins stealing stuff from the hospital to furnish it. Callie and Erica continue their friendship.
4-13 (74)"Piece of My Heart"[114]Stacy McKeeMark TinkerMay 1, 2008 (2008-05-01)15.11
Addison (Kate Walsh) returns to Seattle Grace to perform an operation and is surprised by all the changes in the lives of her former co-workers; Derek and Meredith's clinical trial has its first patient (Jason O'Mara); Rebecca returns with shocking news for Alex.
4-14 (75)"The Becoming"[115]Tony Phelan and Joan RaterJulie Anne RobinsonMay 8, 2008 (2008-05-08)15.60
A "date and tell" policy is instated at Seattle Grace after the nurses object to Mark's trysts, Cristina has to face her feelings for Burke and Meredith and Derek admit a gay veteran soldier into their clinical trial.
4-15 (76)"Losing My Mind"[116]Debora CahnJames FrawleyMay 15, 2008 (2008-05-15)15.18
Dr. Wyatt (Amy Madigan) refuses to let Meredith give up on therapy, Alex learns the truth about Rebecca's medical condition, the Chief insists that Erica perform a risky surgery on his mentor, and after receiving news of Burke, Cristina continues to do things contrary to her nature, going so far as cleaning her always-messy apartment.
4-16 (77)"Freedom, Part 1"[117]Shonda RhimesRob CornMay 22, 2008 (2008-05-22)18.09
Part one of a two-hour season finale. Meredith and Derek work on their last patient (Jurnee Smollett) in their clinical trial, as the other surgeons try desperately to free a boy from a hardening block of cement. Izzie helps Alex care for Rebecca, and Lexie discovers important information about George's intern status. Callie confronts her feelings about Erica.
4-17 (78)"Freedom, Part 2"[118]Shonda RhimesRob CornMay 22, 2008 (2008-05-22)18.09
Part two of a two-hour season finale. Meredith and Derek work on their last patient in their clinical trial, as the other surgeons try desperately to free a boy from a hardening block of cement. Izzie helps Alex care for Rebecca, and Lexie discovers important information about George's intern status. Callie confronts her feelings about Erica.

Season 5: 2008–2009

Episode Title Written by Directed by Premiere Viewers (m)
5-01 (79)"Dream a Little Dream of Me, Part 1"[119]Shonda RhimesRob CornSeptember 25, 2008 (2008-09-25)18.47
A military doctor piques Cristina's interest -- and she helps him -- and he helps her when she gets stabbed by an icicle. Meredith and Derek attempt to work on their "happily ever after", and the attendings are stressed over Seattle Grace's ranking of #12.
5-02 (80)"Dream a Little Dream of Me, Part 2"[120]Shonda RhimesRob CornSeptember 25, 2008 (2008-09-25)18.47
Alex is offended when Izzie talks to Meredith about how great of a man Alex is. Derek is stabbed with the scalpel in the palm of his hand by Rose, while the Chief is stunned over Mercy West's increase in the number of patients, a deadly ice storm ravages Seattle.
5-03 (81)"Here Comes the Flood"[121]Krista VernoffMichael PressmanOctober 9, 2008 (2008-10-09)14.80
A plumbing leak causes a flood at Seattle Grace, as the Chief tries to implement new teaching policies and George retakes his intern exam. Derek tries to move Izzie and Alex out of Meredith's house.
5-04 (82)"Brave New World"[122]Debora CahnEric StoltzOctober 16, 2008 (2008-10-16)14.80
Meredith freaks out when Derek discovers her mother's old diary in the house, Callie frets as she prepares for her first official date with Erica, and Cristina stumbles into a part of the hospital that neither she nor her fellow residents have seen before.
5-05 (83)"There's No 'I' in Team"[123]Jenna BansRandy ZiskOctober 23, 2008 (2008-10-23)14.45
Bailey heads up a team of surgeons performing a "domino procedure" in which each surgery hinges on the one preceding it. Derek gets sole credit for the brain tumor study he did with Meredith. Lexie goes to great lengths to have George notice her romantically, and Sloan counsels a desperate Callie on the ways of love.
5-06 (84)"Life During Wartime"[124]Mark WildingJim FrawleyOctober 30, 2008 (2008-10-30)15.32
To help Bailey become the best general surgeon at Seattle Grace, the Chief gives her new power, new responsibility, and the challenge of removing a young girl's inoperable tumor. The new head of trauma, Owen Hunt, challenges both the attending doctor's methods and the residents' surgical abilities.
5-07 (85)"Rise Up"[125]William HarperJoanna KernsNovember 6, 2008 (2008-11-06)15.74
The Chief announces to the residents that a solo surgery will be awarded, and the news sends them into a competitive frenzy. Meanwhile Derek turns to Bailey for advice when he feels Cristina is interfering in his relationship with Meredith, and another dark day in Izzie's career rises when Erica discovers a shocking connection between her and a longtime patient.
5-08 (86)"These Ties That Bind"[126]Stacy McKeeEric StoltzNovember 13, 2008 (2008-11-13)14.90
One of Meredith's oldest friends, Sadie (Melissa George), becomes an intern at Seattle Grace, but Mer's friends are less than welcoming to her. Lexie leads her fellow interns in secretive, unorthodox surgical training sessions; and a new surgeon, Virginia Dixon (Mary McDonnell), brings rules and order to the OR.
5-09 (87)"In the Midnight Hour"[127]Tony Phelan and Joan RaterTom VericaNovember 20, 2008 (2008-11-20)15.91
Meredith, Cristina and Bailey come to Lexie and Sadie's rescue when a not-so-routine surgery goes horribly wrong, as Owen and Derek treat a man seriously injured while sleepwalking and Mark comforts the sleepwalker's distraught daughter and has feelings for Lexie.
5-10 (88)"All By Myself"[128]Peter NowalkArlene SanfordDecember 4, 2008 (2008-12-04)15.23
Cristina is awarded the first solo surgery among the residents, but she has to relinquish it and choose her replacement; Mark performs a cutting-edge procedure to restore a patient's speech, impressing Lexie in the process; and Callie cannot figure out if Sadie (Melissa George) is flirting with her or just being friendly.
5-11 (89)"Wish You Were Here"[129]Debora CahnRob CornJanuary 8, 2009 (2009-01-08)13.87
Bailey teams with Seattle Grace's new pediatric surgeon, Dr. Arizona Robbins, to save the life of a young patient near and dear to her heart, as the admittance of a death row inmate (Eric Stoltz) at the hospital stirs anger in Derek and further erodes Meredith and Cristina's friendship; meanwhile, Callie and Sloan work as a team to fight their respective attractions to Sadie and Lexie, and Izzie tells Alex that she is seeing Denny.
5-12 (90)"Sympathy for the Devil"[130]Jenna BansJeannot SzwarcJanuary 15, 2009 (2009-01-15)13.10
Derek's mother, Carolyn (Tyne Daly), makes a surprise visit to Seattle and meets Meredith for the first time, as Mark tries to conceal his relationship with Lexie from her as well; meanwhile, death row inmate William (Eric Stoltz) wishes to donate his organs to Bailey and Arizona's patient, as Owen and Cristina try to go on their first date.
5-13 (91)"Stairway to Heaven"[131]Mark WildingAllison LiddiJanuary 22, 2009 (2009-01-22)14.43
Bailey grows desperate as a patient's condition becomes more and more dire. Everyone in the hospital is stepping up to try to find the boy a new organ donor, including Meredith, who considers a death row patient's wish to die before execution. Meanwhile, an injury leaves Mark in a compromising position in the on-call room and Cristina awkwardly avoids Owen. Izzie is still struggling with Denny as he is constantly reminding her "He is there for her". Izzie has an emotional blow out with Denny and soon understands what he is trying to tell her. She finally comes to the realization that Denny is not here "for her" in the emotional sense, which leaves Izzie reeling when she soon discovers that she is sick. Jeffrey Dean Morgan Guest stars.
5-14 (92)"Beat Your Heart Out"[132]William HarperJulie Anne RobinsonFebruary 5, 2009 (2009-02-05)15.20
Now that Derek has the engagement ring, he searches for the perfect way to propose to Meredith, as Lexie demands that Mark go public with their relationship, and Bailey, encouraged by her work on recent cases and by Dr. Dixon (Mary McDonnell), considers a new direction for her medical career. Dr. Dixon suggests that Dr. Bailey will make a good pediatric surgeon. As Derek finally decides to propose to Meredith, Addison calls him, and he decides to postpone the proposal. Cross-over with Private Practice
5-15 (93)"Before and After"[133]Tony Phelan and Joan RaterDan AttiasFebruary 12, 2009 (2009-02-12)15.70
Addison (Kate Walsh), Naomi (Audra McDonald) and Sam (Taye Diggs) rush the ailing Archer to Seattle Grace and reunite with old friends Derek and Mark to help save his life; meanwhile, Izzie employs her fellow doctors in a medical game designed to help teach the interns, and Owen runs into a significant someone from his past. Cross-over with Private Practice.
5-16 (94)"An Honest Mistake"[134]Peter NowalkRandy ZiskFebruary 19, 2009 (2009-02-19)15.39
Derek's confidence is shaken like never before as he faces off with Addison (Kate Walsh) over what course is best for their dying pregnant patient; Cristina calls the abilities of a renowned surgeon (Faye Dunaway) into question after she botches a standard procedure; and Bailey, who has decided to pursue a fellowship in Pediatric Surgery, is appalled by the Chief's less-than-stellar recommendation letter. Cross-over with Private Practice
5-17 (95)"I Will Follow You Into the Dark"[135]Jenna BansRob CornMarch 12, 2009 (2009-03-12)13.54
Izzie walks the interns through diagnosing Patient X after receiving her troubling test results. Bailey and Meredith perform a surgery where they remove a woman's stomach to protect her from a very invasive form of stomach cancer that runs in her family. Hunt and Karev treat a high school marching band player with seizures. Shepherd has to come to grips with killing one of his patients. Cristina receives some disturbing news from one of her colleagues.
5-18 (96)"Stand By Me"[136]Zoanne ClackJessica YuMarch 19, 2009 (2009-03-19)14.67
After his fellow surgeons try and fail to bring Derek back to work, Meredith must summon the strength to convince him. Meanwhile the hospital is abuzz as Mark attempts a rare face transplant surgery. Cristina, at last awarded her first solo surgery, is more focused on the needs of her friends, and Izzie does her best to keep her medical condition a secret.
5-19 (97)"Elevator Love Letter"[137]Stacy McKeeEd OrnelasMarch 26, 2009 (2009-03-26)16.10
All eyes are on Derek as he is set to perform his first surgery after his breakdown; attention is also set on Izzie, whose medical condition requires her to undergo a difficult surgery; and Owen has another PTSD episode that injures Cristina and traumatizes both of them, throwing the future of their relationship into question. Derek proposes to Meredith in the elevator.
5-20 (98)"Sweet Surrender"[138]Sonay WashingtonTony PhelanApril 23, 2009 (2009-04-23)13.55
As she endures aggressive treatment for her cancer, Izzie throws herself into planning Derek and Meredith's wedding, Callie introduces Arizona as her girlfriend to her disapproving father (Hector Elizondo), George excels in a trauma emergency when Alex freezes, and Owen seeks help with his PTSD from Dr. Wyatt (Amy Madigan). Meanwhile, Bailey learns of the heart-wrenching practices in peds.
5-21 (99)"No Good at Saying Sorry"[139]Krista VernoffTom VericaApril 30, 2009 (2009-04-30)14.12
As preparations continue for Meredith and Derek's wedding, Izzie receives a surprise hospital visit from her handful-of-a-mother, Robbie. Meanwhile, a newly sober Thatcher visits his daughters, Meredith and Lexie, in order to make amends. The Chief and Meredith bitterly fight over a controversial medical case.
5-22 (100)"What a Difference a Day Makes"[140]Shonda RhimesRob CornMay 7, 2009 (2009-05-07)15.33
As Meredith, Derek and all of their friends prepare for the big wedding, a group of college students, injured in a car crash as they were heading to their graduation ceremony, is admitted to the ER. Meanwhile, Izzie fears the worst when she begins experiencing familiar symptoms. It turns out she has another brain tumor, which makes Derek and Meredith give their wedding to Izzie and Alex who get married instead.
5-23 (101)"Here's to the Future"[141]Allan HeinbergBill D'EliaMay 14, 2009 (2009-05-14)15.58
Izzie spends time with a fellow cancer patient and contemplates whether or not to undergo a risky surgery, as Mark is ready to take his relationship with Lexie to the next level and a patient makes Owen reassess his place at Seattle Grace. Izzie's surgery to remove the brain tumor could have dire consequences.
5-24 (102)"Now or Never"[142]Debora CahnRob CornMay 14, 2009 (2009-05-14)17.12
George delivers stunning news to Bailey, sending shock-waves throughout the hospital, and Izzie's friends await her recovery from surgery. Meanwhile Bailey is surprisingly displeased after being accepted into the pediatric fellowship program. The doctors focus on the victim of a near-fatal traffic accident who is disfigured and unable to speak. Meredith discovers it's George, who was hit by a bus while saving the woman who accompanied him to the hospital. Izzie recovers her memory and tells Alex that she loves him before losing consciousness. The episode ends with both George and Izzie flatlining and meeting up with each other in a heaven-like scene, with no definite indication of whether either or both are dead or alive.

Season 6: 2009–2010

Episode Title Written by Directed by Premiere Viewers (m)
6-01 (103)"Good Mourning"[143]Krista VernoffEd OrnelasSeptember 24, 2009 (2009-09-24)[144]17.06
Izzie has a bad wake-up call; George's death. Meredith and the other residents fear to continue with their lives as George's death is a major impact to them all.
6-02 (104)"Goodbye"[145]Krista VernoffBill D'EliaSeptember 24, 2009 (2009-09-24)[144]16.52
Cristina and Owen are finding it difficult to abstain from sex as instructed by Dr. Wyatt. Meredith and Derek consumate their wedding everywhere they go. Izzie mourns her best friend, George, after his death. Richard announces Seattle Grace will be merging with Mercy West.
6-03 (105)"I Always Feel Like Somebody's Watchin' Me"[146]Tony Phelan and Joan RaterMichael PressmanOctober 1, 2009 (2009-10-01)15.70
Bailey and Alex's patient is complicated when her schizophrenic son arrives. The residents and interns of Seattle Grace compete to survive the budget cuts.
6-04 (106)"Tainted Obligation"[147]Jenna BansTom VericaOctober 8, 2009 (2009-10-08)13.79
When Meredith and Lexie's father, Thatcher, returns to the hospital with a failed liver, it's up to Meredith to save his life. Meanwhile, Izzie empathizes with a patient riddled with tumors, as Mark, annoyed with Cristina's competitive zeal, tricks her into assisting on an unusual surgery.
6-05 (107)"Invasion"[148]Mark WildingTony PhelanOctober 15, 2009 (2009-10-15)13.86
The residents of Seattle Grace and Mercy West vie for surgeries and their careers as day one of the hospital merger begins. Meanwhile, Arizona stands by an enraged Callie when her father visits with a priest to attempt to convince her to renounce her homosexuality; Izzie experiences the brunt of the new surgical competition; and an accident derails a patient's upcoming kidney donation, with Dr. Bailey promising to set things right, segueing into a crossover with Private Practice. Izzie is fired and leaves a Dear John letter for Alex and disappears.
6-06 (108)"I Saw What I Saw"William HarperAllison Liddi-BrownOctober 22, 2009 (2009-10-22)15.06
After a burn victim unexpectedly dies in the midst of a chaotic ER, the Chief and board member Jennings interrogate the residents to find the culprit, as all the Mercy West and Seattle Grace residents defend their actions in an effort to save their jobs. April Kepner (Sarah Drew) is fired.
6-07 (109)"Give Peace A Chance"Peter NowalkChandra WilsonOctober 29, 2009 (2009-10-29)13.73
Derek must help the unlikeliest of all; the hospital lab-tech, Isaac, when it turns out that he has an inoperable tumor surrounding his spine. Derek is juggling two things at once when he questions Richard's authority.
6-08 (110)"Invest In Love"Stacy McKeeJessica YuNovember 5, 2009 (2009-11-05)13.92
Arizona is stunned when her longtime patient's parents offer the hospital a donation of twenty-five million dollars, but when her patient's condition worsens, all eyes are on her to save him. Cristina tests her relationship when she blatantly disregards Owen's orders and performs an unauthorised cardiac procedure, then later kisses Mercy Wester Jackson Avery at a surprise party for Arizona. Alex cares for a struggling newborn while Izzie remains missing. In the wake of great grief, Arizona and Callie take their relationship to the next level.
6-09 (111)"New History"Allan HeinbergRob CornNovember 12, 2009 (2009-11-12)14.86
When Owen recruits his fellow Iraqi War vet, Dr. Teddy Altman (Kim Raver), as the new cardiothoracic surgeon, Cristina questions Teddy's abilities in the OR and the nature of their past relationship. Meanwhile Izzie returns to Seattle Grace with her high school mentor (Joel Grey) seeking treatment for his dementia, and the stress of Richard's responsibilities, post-merger, are taking their toll.
6-10 (112)"Holidaze"Krista VernoffRobert BerlingerNovember 19, 2009 (2009-11-19)14.07
As Thanksgiving, Christmas and New Year's pass, Miranda is visited by her father, William, who disapproves of her choices in life. Meanwhile, Mark and Lexie must cope with the shocking arrival of a woman from his past, his "daughter". Thatcher Grey questions the Chief's recent behavior as Meredith comes to his defense. Cristina suspects that there is/was something going on between Owen and Teddy.
6-11 (113)"Blink"Debora CahnRandy ZiskJanuary 14, 2010 (2010-01-14)12.73
Part 1 of a Grey's Anatomy/Private Practice crossover. Mark flies Addison (Kate Walsh) to Seattle to help with a difficult procedure on his pregnant daughter, Sloan,which creates tensions between him and Lexie leading to their break-up. Owen questions Teddy’s motives when she assigns Cristina the lead on a complicated surgery, and Derek’s suspicions are raised when the Chief recruits Bailey to assist with a high profile operation.
6-12 (114)"I Like You So Much Better When You're Naked"Tony Phelan and Joan RaterDonna DeitchJanuary 21, 2010 (2010-01-21)TBA
After learning of Richard's drinking problem, Derek confronts him for the sake of his friend and the hospital, Izzie returns, hoping to reconcile with Alex, and tensions run high between Teddy, Cristina and Owen in the aftermath of Teddy's startling confession.
6-13 (115)"State of Love and Trust"Stacy McKeeJeannot SzwarcFebruary 4, 2010 (2010-02-04)TBA
As Derek begins his role as interim chief, he faces a potential lawsuit when Bailey and Meredith's patient awakens from anesthesia mid-surgery. Meanwhile, Teddy refuses to place Cristina on her service, as Arizona tests Alex out in Pediatrics, and Mark refuses to speak to a heartbroken Lexie. Derek tries to convince Richard to seek treatment for his drinking.
6-14 (116)"TBA"William HarperTBAFebruary 11, 2010 (2010-02-11)TBA
A Valentine's Day-themed episode.
6-15 (117)"Time Warp"TBATBAFebruary 18, 2010 (2010-02-18)TBA
The flashback-heavy hour sheds light on the beginnings of the affair between the Chief (played by J. August Richards) and Ellis (Sarah Paulson) in 1982. In separate 2004 sequences, viewers see Bailey in her pre-”Nazi” days and Callie shortly before she was introduced on the show.[1]
6-16 (118)"TBA"TBATBATBATBA
6-17 (119)"TBA"TBATBATBATBA
6-18 (120)"TBA"TBATBATBATBA
6-19 (121)"TBA"Allan HeinbergTBATBATBA

Specials

Season (No.) Title Until Narrator Original Airdate
2 (1)"Straight to the Heart"2-12 (21)Steven W. Bailey as JoeJanuary 8, 2006 (2006-01-08)
Joe the Bartender narrates a special episode featuring clips from the first two seasons used in order to orient new viewers and recap memorable moments.
2 (2)"Under Pressure"2-22 (31)Steven W. Bailey as JoeApril 23, 2006 (2006-04-23)
A special recap episode detailing the 10 previously aired episodes of the series' second season.
3 (3)"Complications of the Heart"2-27 (36)Steven W. Bailey as JoeSeptember 21, 2006 (2006-09-21)
A special recap episode detailing the remaining episodes of season two with insight on future episodes of season 3. The special also marked the debut of The Fray's music video, "How to Save a Life" with clips from Grey's Anatomy episodes.
3 (4)"Every Moment Counts"3-19 (55)Jeffrey Dean Morgan as Denny DuquetteApril 12, 2007 (2007-04-12)
Jeffrey Dean Morgan, who plays the role of "Denny", hosts a one-hour special which highlights some of the most memorable moments from the last three seasons. The special also included an exclusive, world broadcast premiere "Grey's Anatomy" music video set to singer-songwriter Brandi Carlile's song, "The Story."
4 (5)"Come Rain or Shine: From Grey's Anatomy to Private Practice"3-25 (61)Editors of PeopleSeptember 19, 2007 (2007-09-19)
This episode recaps all of the seasons of Grey's Anatomy, relating Addison's story and previewing her spin-off series Private Practice.

Webisodes

Episode No. Title Original Airdate
1"Seattle Grace: On Call Part 1"November 20, 2009 (2009-11-20)
Documentary style, focused at Joe's Bar. Joe is hosting a New Year's Eve party, and many doctors are there. Charlie has feelings for Reed, but she just thinks of him as a friend. Pierce is there with Graciella, but when Megan and Steve arrive, it's clear that he still has feelings for her.
2"Seattle Grace: On Call Part 2"December 3, 2009 (2009-12-03)
The Seattle Gracer's stand in for Joe's no show band. Megan and Pierce have an argument that ends in tears.
3"Seattle Grace: On Call Part 3"December 10, 2009 (2009-12-10)
The band disbanded, and Steve and Megan are playing at Joe's as a duet. Pierce urges Megan to take a paternity test. Ryan hits on Reed to Charlie's dismay.
4"Seattle Grace: On Call Part 4"December 17, 2009 (2009-12-17)
Reed and Ryan are together. Reed urges Charlie to hook up with Graciella, who is flirting with him. Megan takes the paternity test, but decides not to open it. Pierce finds out Megan took the test from a nurse. He confronts her at Joe's, and Steve overhears.
5"Seattle Grace: On Call Part 5"January 14, 2010 (2010-01-14)
Pierce, Steve, and Megan argue, which ends in a physical fight between Pierce and Steve. Megan finds out the results of the paternity test.
6"Seattle Grace: On Call Part 6"January 21, 2010 (2010-01-21)
TBA

References

  1. ^ "Season Program Rankings from 09/20/04 through 05/22/06". ABC Medianet. May 24, 2005. Retrieved 2009-07-03.
  2. ^ "Season Program Rankings from 09/19/05 through 05/28/06". ABC Medianet. May 28, 2006. Retrieved 2009-07-03.
  3. ^ "Season Program Rankings from 09/18/06 through 06/03/07". ABC Medianet. June 3, 2007. Retrieved 2009-07-03.
  4. ^ "Season Program Rankings from 09/24/07 through 05/25/08". ABC Medianet. May 28, 2008. Retrieved 2009-07-03.
  5. ^ "Season Program Rankings from 09/22/08 through 05/17/09". ABC Medianet. May 19, 2009. Retrieved 2009-07-03.
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  147. ^ "GREY'S ANATOMY: Tainted Obligation (10/8)". 10 October 2009.
  148. ^ "GREY'S ANATOMY: Invasion (10/15)". 10 October 2009.