Jump to content

3-hydroxybenzoate 2-monooxygenase

From Wikipedia, the free encyclopedia

This is an old revision of this page, as edited by BrownHairedGirl (talk | contribs) at 08:44, 23 September 2019 (replace link to deleted Portal:Molecular and cellular biology (+aliases) with Portal:Biology). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

3-hydroxybenzoate 2-monooxygenase
Identifiers
EC no.1.14.99.23
CAS no.73507-96-7
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a 3-hydroxybenzoate 2-monooxygenase (EC 1.14.99.23) is an enzyme that catalyzes the chemical reaction

3-hydroxybenzoate + AH2 + O2 2,3-dihydroxybenzoate + A + H2O

The 3 substrates of this enzyme are 3-hydroxybenzoate, an electron acceptor AH2, and O2, whereas its 3 products are 2,3-dihydroxybenzoate, the reduction product A, and H2O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derive from O miscellaneous. The systematic name of this enzyme class is 3-hydroxybenzoate,hydrogen-donor:oxygen oxidoreductase (2-hydroxylating). Other names in common use include 3-hydroxybenzoate 2-hydroxylase, and 3-HBA-2-hydroxylase. This enzyme participates in benzoate degradation via hydroxylation.

References

  • Daumy GO, McColl AS (1982). "Induction of 3-hydroxybenzoate 2-hydroxylase in a Pseudomonas testosteroni mutant". J. Bacteriol. 149 (1): 384–5. PMC 216637. PMID 7054148.