Abietadiene hydroxylase
| Abieta-7,13-diene hydroxylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.14.13.108 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Abieta-7,13-diene hydroxylase (EC 1.14.13.108) is an enzyme with systematic name abieta-7,13-diene,NADPH:oxygen oxidoreductase (18-hydroxylating).[1][2] This enzyme catalyses the following chemical reaction
- abieta-7,13-diene + NADPH + H+ + O2 abieta-7,13-dien-18-ol + NADP+ + H2O
Abietadiene hydroxylase is a heme-thiolate protein (P-450).
References
- ^ Funk C, Croteau R (January 1994). "Diterpenoid resin acid biosynthesis in conifers: characterization of two cytochrome P450-dependent monooxygenases and an aldehyde dehydrogenase involved in abietic acid biosynthesis". Archives of Biochemistry and Biophysics. 308 (1): 258–66. doi:10.1006/abbi.1994.1036. PMID 8311462.
- ^ Funk C, Lewinsohn E, Vogel BS, Steele CL, Croteau R (November 1994). "Regulation of Oleoresinosis in Grand Fir (Abies grandis) (Coordinate Induction of Monoterpene and Diterpene Cyclases and Two Cytochrome P450-Dependent Diterpenoid Hydroxylases by Stem Wounding)". Plant Physiology. 106 (3): 999–1005. doi:10.1104/pp.106.3.999. PMC 159624. PMID 12232380.
External links
- Abieta-7,13-diene+hydroxylase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
