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Benzoyl-CoA 2,3-dioxygenase

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Benzoyl-CoA 2,3-dioxygenase
Identifiers
EC no.1.14.12.21
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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NCBIproteins

Benzoyl-CoA 2,3-dioxygenase (EC 1.14.12.21, benzoyl-CoA dioxygenase/reductase, BoxBA, BoxA/BoxB system) is an enzyme with systematic name benzoyl-CoA,NADPH:oxygen oxidoreductase (2,3-hydroxylating).[1][2][3] This enzyme catalyses the following chemical reaction

benzoyl-CoA + NADPH + H+ + O2 2,3-dihydro-2,3-dihydroxybenzoyl-CoA + NADP+

Benzoyl-CoA 2,3-dioxygenase is involved in aerobic benzoate metabolism in Azoarcus evansii.

References

  1. ^ Zaar A, Gescher J, Eisenreich W, Bacher A, Fuchs G (October 2004). "New enzymes involved in aerobic benzoate metabolism in Azoarcus evansii". Molecular Microbiology. 54 (1): 223–38. doi:10.1111/j.1365-2958.2004.04263.x. PMID 15458418.
  2. ^ Gescher J, Zaar A, Mohamed M, Schägger H, Fuchs G (November 2002). "Genes coding for a new pathway of aerobic benzoate metabolism in Azoarcus evansii". Journal of Bacteriology. 184 (22): 6301–15. doi:10.1128/jb.184.22.6301-6315.2002. PMC 151953. PMID 12399500.
  3. ^ Mohamed ME, Zaar A, Ebenau-Jehle C, Fuchs G (March 2001). "Reinvestigation of a new type of aerobic benzoate metabolism in the proteobacterium Azoarcus evansii". Journal of Bacteriology. 183 (6): 1899–908. doi:10.1128/JB.183.6.1899-1908.2001. PMC 95084. PMID 11222587.