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CM156

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This is an old revision of this page, as edited by DMacks (talk | contribs) at 15:08, 21 June 2020 (Remove malformatted |molecular_weight= when infobox can autocalculate it, per Wikipedia talk:WikiProject Pharmacology#Molecular weights in drugboxes (via WP:JWB)). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

CM156
Identifiers
  • 3-[4-(4-cyclohexylpiperazin-1-yl)butyl]-1,3-benzothiazole-2-thione
PubChem CID
ChemSpider
Chemical and physical data
FormulaC21H31N3S2
Molar mass389.62 g·mol−1
3D model (JSmol)
  • c1ccc2c(c1)n(c(=S)s2)CCCCN3CCN(CC3)C4CCCCC4
  • InChI=1S/C21H31N3S2/c25-21-24(19-10-4-5-11-20(19)26-21)13-7-6-12-22-14-16-23(17-15-22)18-8-2-1-3-9-18/h4-5,10-11,18H,1-3,6-9,12-17H2
  • Key:FJGOTAJCEJCFEV-UHFFFAOYSA-N

CM156[1] is a piperazine based chemical compound with nanomolar affinity for both sigma receptor subtypes that has been shown to counteract the deleterious effects of administered cocaine.

See also

References

  1. ^ Xu YT, Kaushal N, Shaikh J, Wilson LL, Mésangeau C, McCurdy CR, Matsumoto RR (May 2010). "A novel substituted piperazine, CM156, attenuates the stimulant and toxic effects of cocaine in mice". The Journal of Pharmacology and Experimental Therapeutics. 333 (2): 491–500. doi:10.1124/jpet.109.161398. PMC 2872963. PMID 20100904.
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