Butirosin

From Wikipedia, the free encyclopedia
Butirosin
INN: Butirosin
Butirosin A structure.svg
Butirosin B structure.svg
Butirosin A (top) and butirosin B (bottom)
Clinical data
Other namesAmbutyrosin; Butyrosin
Drug classAminoglycoside antibiotic
Identifiers
CAS Number
UNII
ChEBI
CompTox Dashboard (EPA)
Chemical and physical data
3D model (JSmol)
  • C1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1NC(=O)[C@@H](CCN)O)O)O[C@@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CN)O)O)N)N

Butirosin is an aminoglycoside antibiotic complex which is active against both Gram-positive and Gram-negative bacteria.[1] It is a mixture with butirosin A (80-85%) and butirocin B being the major components.[2]

References[edit]

  1. ^ Heifetz CL, Fisher MW, Chodubski JA, DeCarlo MO (August 1972). "Butirosin, a new aminoglycosidic antibiotic complex: antibacterial activity in vitro and in mice". Antimicrobial Agents and Chemotherapy. 2 (2): 89–94. doi:10.1128/aac.2.2.89. PMC 444273. PMID 4670492.
  2. ^ Elks J (2014). The Dictionary of Drugs. Springer. p. 198.