X-His dipeptidase

From Wikipedia, the free encyclopedia
  (Redirected from Carnosinase)
Jump to: navigation, search
Xaa-His dipeptidase
Identifiers
EC number 3.4.13.3
CAS number 9027-21-8
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Xaa-His dipeptidase (EC 3.4.13.3, aminoacylhistidine dipeptidase, carnosinase, homocarnosinase, dipeptidase M) is an enzyme.[1][2][3][4] This enzyme catalyses the following chemical reaction

Hydrolysis of Xaa!His dipeptides

This mammalian cytosolic enzyme also acts on anserine and homocarnosine.

References[edit]

  1. ^ Hanson, H.T. and Smith, E.L. (1949). "Carnosinase: an enzyme of swine kidney". J. Biol. Chem. 179: 789–801. 
  2. ^ Rosenberg, A. (1960). "The activation of carnosinase by divalent ions". Biochim. Biophys. Acta 45: 297–316. doi:10.1016/0006-3002(60)91454-2. PMID 13743376. 
  3. ^ Lenney, J.F., Kan, S.C., Siu, K. and Sugiyama, G.H. (1977). "Homocarnosinase: a hog kidney dipeptidase with a broader specificity than carnosinase". Arch. Biochem. Biophys. 184 (1): 257–266. doi:10.1016/0003-9861(77)90349-6. PMID 21630. 
  4. ^ Lenney, J.F. (1990). "Separation and characterization of 2 carnosine-splitting cytosolic dipeptidases from hog kidney (carnosinase and nonspecific dipeptidase)". Biol. Chem. Hoppe-Seyler 371: 433–440. doi:10.1515/bchm3.1990.371.1.433. PMID 2378680. 

External links[edit]