Dinoflagellate luciferase
| Dinoflagellate luciferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.13.12.18 | ||||||||
| CAS no. | 303183-71-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Dinoflagellate luciferase (EC 1.13.12.18, Gonyaulax luciferase) is a specific luciferase, an enzyme with systematic name dinoflagellate-luciferin:oxygen 132-oxidoreductase.[1][2][3][4][5][6] This enzyme catalyses the following chemical reaction
- dinoflagellate luciferin + O2 oxidized dinoflagellate luciferin + H2O + hnu
Dinoflagellate luciferase is a single protein with three luciferase domains.
References
- ^ Dunlap, J.C.; Hastings, J.W. (1981). "The biological clock in Gonyaulax controls luciferase activity by regulating turnover". J. Biol. Chem. 256 (20): 10509–10518. PMID 7197271.
- ^ Morse, D.; Pappenheimer, A.M.; Jr.; Hastings, J.W. (1989). "Role of a luciferin-binding protein in the circadian bioluminescent reaction of Gonyaulax polyedra". J. Biol. Chem. 264 (20): 11822–11826. PMID 2745419.
- ^ Bae, Y.M.; Hastings, J.W. (1994). "Cloning, sequencing and expression of dinoflagellate luciferase DNA from a marine alga, Gonyaulax polyedra". Biochim. Biophys. Acta. 1219 (2): 449–456. doi:10.1016/0167-4781(94)90071-x. PMID 7918642.
- ^ Li, L. (2000). "Gonyaulax luciferase: gene structure, protein expression, and purification from recombinant sources". Methods Enzymol. 305: 249–258. doi:10.1016/s0076-6879(00)05492-6. PMID 10812605.
- ^ Morse, D.; Mittag, M. (2000). "Dinoflagellate luciferin-binding protein". Methods Enzymol. 305: 258–276. doi:10.1016/s0076-6879(00)05493-8. PMID 10812606.
- ^ Schultz, L.W.; Liu, L.; Cegielski, M.; Hastings, J.W. (2005). "Crystal structure of a pH-regulated luciferase catalyzing the bioluminescent oxidation of an open tetrapyrrole". Proc. Natl. Acad. Sci. USA. 102: 1378–1383. doi:10.1073/pnas.0409335102. PMC 547824. PMID 15665092.
External links
- Dinoflagellate+luciferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)