Gingipain

Gingipain is a protease secreted by Porphyromonas gingivalis. Among other functions, they work to degrade cytokines, thereby downregulating the host response in the form of reduced inflammation.^[1]

References

^ Stathopoulou, PG. Epithelial cell pro-inflammatory cytokine response differs across dental plaque bacterial species. J Clin Perio 2010;37:24–29

v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)