HLA-DMA

HLA-DMA
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1HDM, 2BC4, 4FQX, 4GBX
Identifiers
Aliases	HLA-DMA, D6S222E, DMA, HLADM, RING6, major histocompatibility complex, class II, DM alpha
External IDs	OMIM: 142855 MGI: 95921 HomoloGene: 4464 GeneCards: HLA-DMA
Gene location (Human)
Chr.	Chromosome 6 (human)
End	32,969,094 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	34,358,075 bp
RNA expression pattern
	Top expressed in
	monocyte; ; lymph node; ; spleen; ; appendix; ; gallbladder; ; upper lobe of left lung; ; right lung; ; duodenum; ; rectum; ; subcutaneous adipose tissue;
	Top expressed in
	spleen; ; thymus; ; blood; ; subcutaneous adipose tissue; ; jejunum; ; Paneth cell; ; sciatic nerve; ; ankle joint; ; lip; ; duodenum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	MHC class II protein complex binding; protein binding;
Cellular component	integral component of membrane; cell surface; endosome; lysosome; extracellular exosome; late endosome membrane; membrane; lysosomal membrane; MHC class II protein complex; intracellular membrane-bounded organelle;
Biological process	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; peptide antigen assembly with MHC class II protein complex; antigen processing and presentation; antigen processing and presentation of exogenous peptide antigen via MHC class II; immune response; immune system process; adaptive immune response;
	Sources:Amigo / QuickGO
Orthologs
	3108
	14998
ENSG00000243215; ENSG00000243719; ENSG00000239463; ENSG00000204257; ENSG00000242361;
	ENSG00000241394; ENSG00000243189; ENSG00000242685
	ENSMUSG00000037649
	P28067
	P28078; Q31621
	NM_006120
	NM_010386; NM_001360530
	n/a
	NP_034516; NP_001347459
	Wikidata
View/Edit Human	View/Edit Mouse

HLA class II histocompatibility antigen, DM alpha chain is a protein that in humans is encoded by the HLA-DMA gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c ENSG00000243719, ENSG00000239463, ENSG00000204257, ENSG00000242361, ENSG00000241394, ENSG00000243189, ENSG00000242685 GRCh38: Ensembl release 89: ENSG00000243215, ENSG00000243719, ENSG00000239463, ENSG00000204257, ENSG00000242361, ENSG00000241394, ENSG00000243189, ENSG00000242685 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000037649 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kelly A, Powis SH, Glynne R, Radley E, Beck S, Trowsdale J (Nov 1991). "Second proteasome-related gene in the human MHC class II region". Nature. 353 (6345): 667–8. doi:10.1038/353667a0. PMID 1922385.
^ "Entrez Gene: HLA-DMA major histocompatibility complex, class II, DM alpha".

v t e Major histocompatibility complex classes
MHC class I	HLA-A HLA-B HLA-C HLA-E HLA-F HLA-G
MHC class II	HLA-DM α β HLA-DO α β HLA-DP α1 β1 HLA-DQ α1 α2 β1 β2 β3 HLA-DR α β1 β3 β4 β5
Other	Human leukocyte antigen Minor histocompatibility antigen Blood transfusion Arrestin Calgranulin Human blood group systems Cell adhesion molecules Cluster of differentiation

References

Further reading