Oxipurinol
Appearance
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Names | |
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Preferred IUPAC name
1,2-Dihydropyrazolo[4,3-e]pyrimidine-4,6-dione | |
Systematic IUPAC name
1H,2H,4H,5H,6H-pyrazolo[3,4-d]pyrimidine-4,6-dione | |
Other names
1H,2H,5H-pyrazolo[3,4-d]pyrimidine-4,6-dione
Alloxanthine | |
Identifiers | |
3D model (JSmol)
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139956 | |
ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.017.792 |
EC Number |
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KEGG | |
MeSH | Oxypurinol |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C5H4N4O2 | |
Molar mass | 152.11086 |
Appearance | white crystals |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Oxypurinol is an inhibitor of xanthine oxidase. It is an active metabolite of allopurinol and it is cleared renally. In cases of renal disease, this metabolite will accumulate to toxic levels. By inhibiting xanthine oxidase, it reduces uric acid production. High serum uric acid levels may result in gout, kidney stones, and other medical conditions.
References