STAG1

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STAG1
Identifiers
Aliases STAG1, SA1, SCC3A, stromal antigen 1
External IDs MGI: 1098658 HomoloGene: 21191 GeneCards: STAG1
RNA expression pattern
PBB GE STAG1 202294 at fs.png

PBB GE STAG1 202293 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005862

NM_009282

RefSeq (protein)

NP_005853

NP_033308.2
NP_033308

Location (UCSC) Chr 3: 136.34 – 136.75 Mb Chr 9: 100.6 – 100.96 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Cohesin subunit SA-1 is a protein that in humans is encoded by the STAG1 gene.[3][4]

Function[edit]

This gene is a member of the SCC3 family and is expressed in the nucleus. It encodes a component of cohesin, a multisubunit protein complex that provides sister chromatid cohesion along the length of a chromosome from DNA replication through prophase and prometaphase, after which it is dissociated in preparation for segregation during anaphase.[4]

Interactions[edit]

STAG1 has been shown to interact with STAG2.[5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Carramolino L, Lee BC, Zaballos A, Peled A, Barthelemy I, Shav-Tal Y, Prieto I, Carmi P, Gothelf Y, González de Buitrago G, Aracil M, Márquez G, Barbero JL, Zipori D (August 1997). "SA-1, a nuclear protein encoded by one member of a novel gene family: molecular cloning and detection in hemopoietic organs". Gene. 195 (2): 151–9. doi:10.1016/S0378-1119(97)00121-2. PMID 9305759. 
  4. ^ a b "Entrez Gene: STAG1 stromal antigen 1". 
  5. ^ Sumara I, Vorlaufer E, Gieffers C, Peters BH, Peters JM (November 2000). "Characterization of vertebrate cohesin complexes and their regulation in prophase". The Journal of Cell Biology. 151 (4): 749–62. doi:10.1083/jcb.151.4.749. PMC 2169443Freely accessible. PMID 11076961. 

Further reading[edit]

External links[edit]