Sodium picosulfate
 | |
| Clinical data | |
|---|---|
| Routes of administration | Oral |
| ATC code | |
| Identifiers | |
| |
| CAS Number | |
| PubChem CID | |
| ChemSpider | |
| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.030.097 |
| Chemical and physical data | |
| Formula | C18H13NNa2O8S2 |
| Molar mass | 481.409 g/mol g·mol−1 |
| 3D model (JSmol) | |
| |
| |
| (verify) | |
Sodium picosulfate (INN, also known as sodium picosulphate) is a contact laxative used as a treatment for constipation or to prepare the large bowel before colonoscopy or surgery. It is sold under the trade names Laxoberal, Picolax, Picoprep,[1] Guttalax and several others.
Effects
Orally administered sodium picosulfate is generally used for emergency evacuation of the bowel, usually for patients who are preparing to undergo a colonoscopy. It works very quickly, so access to a toilet at all times is recommended. It starts off by making bowel movements looser and more frequent, but within an hour or so of taking it the patient should experience diarrhoea.
The most common side effects of picosulfate are abdominal cramps and diarrhoea.
The use of sodium picosulfate has also been associated with certain electrolyte disturbances, such as hyponatremia and hypokalemia.[2]
References
- ^ Picoprep study at ingentaconnect 'Picoprep-3 Is a Superior Colonoscopy Preparation to Fleet: A Randomized, Controlled Trial Comparing the Two Bowel Preparations' study at St George Hospital, Sydney, NSW, Australia
- ^ ADRAC (2002). "Electrolyte disturbances with sodium picosulfate bowel cleansing products". Aust Adv Drug React Bull. 21 (1).
{{cite journal}}: Unknown parameter|month=ignored (help) Free full text from the Australian Therapeutic Goods Administration
Brand Picofast (Sodium Picosulphate) Marketed by Gennext Lifesciences in INDIA.
Kreative Organics in India is an API manufacturer for Sodium Picosulphate
 | This drug article relating to the gastrointestinal system is a stub. You can help Wikipedia by expanding it. |