Talk:Eucalyptol

Toxicity

Does anyone have data on the toxicity and biopharmacology of Eucalyptol? —Preceding unsigned comment added by 203.214.95.150 (talk) 00:40, 18 October 2007 (UTC)

"Eucalyptus oil" is not "Eucalyptol"

I notice that Eucalyptus oil has been redirected to Eucalyptol. Eucalyptol or cineole is the major isolate of standard Eucalyptus oil, but the two are not the same. "Eucalyptus oil" is a generic name for oils specifically from Eucalyptus species only. It would be like saying that citronella oil is the same citronellal - which they are not. So I propose that we separate "Eucalyptus oil" and "Eucalyptol" into seperate headings. John Moss (talk) 11:00, 30 May 2008 (UTC)

WikiProject Food and drink tagging

This article talk page was automatically added with {{WikiProject Food and drink}} banner as it falls under Category:Food or one of its subcategories. If you find this addition an error, Kindly undo the changes and update the inappropriate categories if needed. The bot was instructed to tag these articles upon consensus from WikiProject Food and drink. You can find the related request for tagging here. Maximum and careful attention was done to avoid any wrongly tagging any categories , but mistakes may happen... If you have concerns, please inform on the project talk page -- TinucherianBot (talk) 01:05, 4 July 2008 (UTC)

Please do not auto-direct the topic of....

Martindale: The Extra Pharmacopoeia to other pages, as it is an unique book--222.67.204.146 (talk) 10:44, 5 July 2009 (UTC)

MSDS reference contains no mention of what it's supposed to reference

The MSDS reference is provided as a citation for the claim that it is a reproductive hazard for males and females, yet in the MSDS itself the only hazards it lists are eye/skin irritant. The reference does not support the claim.... 128.163.8.163 (talk) 17:28, 27 September 2012 (UTC)

Assessment comment

The comment(s) below were originally left at Talk:Eucalyptol/Comments, and are posted here for posterity. Following several discussions in past years, these subpages are now deprecated. The comments may be irrelevant or outdated; if so, please feel free to remove this section.

I am creating a talk page here because we need to find a way to handle non-technical but legal terms such as VOC (Volatile Organic Compound) for which there is a seperate existing article and ensure that any VOC's or chemicals that would be regarded as VOC's such as the terpenes get associated by some agreed mechanism that is simple and clear to non-chemists and non-specialists. I also would like to raise the issue of "Flashpoint" and "LD50" being consistently included in the chemical articles but absolutely for those that come into household use and may be searched for. The eucalyptus oil fractions would be a classic case in my experience. Commonly found in households, often appear to be used without any knowledge of potential outcomes or flammability. If this is already dealt with and I have missed it please point it out gently.Celsius100 (talk) 03:16, 14 October 2009 (UTC)

Last edited at 03:16, 14 October 2009 (UTC). Substituted at 14:44, 29 April 2016 (UTC)

External links modified

Hello fellow Wikipedians,

I have just modified one external link on Eucalyptol. Please take a moment to review my edit. If you have any questions, or need the bot to ignore the links, or the page altogether, please visit this simple FaQ for additional information. I made the following changes:

• Added archive https://web.archive.org/web/20090411071437/http://www.pharmacopoeia.co.uk:80/pdf/2009_index.pdf to http://www.pharmacopoeia.co.uk/pdf/2009_index.pdf

When you have finished reviewing my changes, please set the checked parameter below to true or failed to let others know (documentation at {{Sourcecheck}}).

This message was posted before February 2018. After February 2018, "External links modified" talk page sections are no longer generated or monitored by InternetArchiveBot. No special action is required regarding these talk page notices, other than regular verification using the archive tool instructions below. Editors have permission to delete these "External links modified" talk page sections if they want to de-clutter talk pages, but see the RfC before doing mass systematic removals. This message is updated dynamically through the template {{source check}} (last update: 5 June 2024).

• If you have discovered URLs which were erroneously considered dead by the bot, you can report them with this tool.
• If you found an error with any archives or the URLs themselves, you can fix them with this tool.

Cheers.—InternetArchiveBot (Report bug) 00:42, 21 July 2016 (UTC)

Eucalyptus was used as as decongestant plus

Cough drops used to contain eucalyptus oil as.decongestant but the menthol was cough suppressant and analgesic. Reaction with water & sulfuric acid gave "Terpin Hydrate" which was the distinctive taste of traditional Codeine cough syrup. And I assume the reason for removing Eucalyptus oil from cough drops is its a common allergen. Shjacks45 (talk) 10:50, 4 July 2019 (UTC)

Tea tree oil citation

Here’s a citation for its presence in Melaleuca alternifolia https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1360273/ … sorry I don’t have time to figure out all the proper formatting just now. — AlexBayleaf 58.96.87.140 (talk) 09:28, 3 July 2022 (UTC)

Revert struggle on biosynthesis

The biosynthesis of eucalytol can be described concisely. Linalyl pyrophosphate, which the editor refuses to link, converts to eucalytol as mediated by an enzyme cineole synthase. Its not complicated, in fact kind of routine: linalyl pyrophosphate is a common precursor to many terpenes and terpenoids.

Like almost all terpene conversions, the synthase mediates the formation and rearragement of carbocations. That is the "magic" of terpene biosyntheses. Racemic eucalytol is produced. One editor seeks to depict the proposed pathway for each enantiomer, which is redundant and the resulting image is difficult to read. The same editors wishes to describe the excruciating details of conformational changes and the hydrolysis of the ultimate carbocation. A number terpene and terpenoid biosyntheses are described in this encyclopedia, and we rarely describe conformational manipulations by the protein because that is what enzymes do. The hydrolysis of carbo cations (R₃C⁺ + H₂O → R₃COH + H⁺ is routine. The referencing is redundant. So that is my case:

1. cropped image
2. acknowledge the role of linalyl pyrophosphate with link to linalool
3. omit or compress discussion of conformational changes
4. omit or compress description of hydrolysis of carbocation
5. simplify referencing

I have tried to engage the editor on their talk page without any response. --Smokefoot (talk) 13:28, 10 June 2023 (UTC)

I agree with Smokefoot. The version here is concise and clear, with the appropriate biosynthesis image. Zefr (talk) 14:06, 10 June 2023 (UTC)

I think that A365J has misinterpreted the source reference. That article refers to a deuterium-labelling experiment designed to distinguish between two possible mechanisms: both alternatives are shown in File:Eucalyptol synthesis altered versionxyz.gif as uploaded by them but, unhelpfully, without the H_R and H_S of the original scheme 1 in the source. The authors of the article conclude that the right-hand alternative in their Scheme 1 is the true mechanism. Eucalyptol has a plane of symmetry, so there are not two enantiomers to discuss unless (as the source reports) one deliberately uses isotopic labelling to break the symmetry. The version of the article linked above by Zefr is fine but could be improved by a simpler diagram in .svg format, as recommended in MOS:CSDG. I'll provide my own version later. Mike Turnbull (talk) 14:36, 10 June 2023 (UTC)

Good pt about the product being achiral. For some reason the author wanted to show the two enantiomeric precursors though.--Smokefoot (talk) 15:34, 10 June 2023 (UTC)

I've added a new diagram, which I hope everyone can agree is acceptable and shows the key parts of the mechanism. Mike Turnbull (talk) 15:49, 10 June 2023 (UTC)