Timiperone

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Timiperone
Clinical data
Trade namesTolopelon
AHFS/Drugs.comInternational Drug Names
Routes of
administration
By mouth
ATC code
  • none
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
  • 1-(4-fluorophenyl)-4-[4-(2-sulfanylidene-3H-benzimidazol-1-yl)piperidin-1-yl]butan-1-one
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.055.328 Edit this at Wikidata
Chemical and physical data
FormulaC22H24FN3OS
Molar mass397.50 g/mol g·mol−1
3D model (JSmol)
  • C1CN(CCC1N2C3=CC=CC=C3NC2=S)CCCC(=O)C4=CC=C(C=C4)F
  • InChI=1S/C22H24FN3OS/c23-17-9-7-16(8-10-17)21(27)6-3-13-25-14-11-18(12-15-25)26-20-5-2-1-4-19(20)24-22(26)28/h1-2,4-5,7-10,18H,3,6,11-15H2,(H,24,28) ☒N
  • Key:YDLQKLWVKKFPII-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Timiperone, sold under the brand name Tolopelon, is an antipsychotic of the butyrophenone class which is marketed in Japan.[1][2][3] It is similar in chemical structure to benperidol but has a thiourea group instead of a urea group.

References

  1. ^ Index Nominum 2000: International Drug Directory. Taylor & Francis. 2000. pp. 1030–. ISBN 978-3-88763-075-1.
  2. ^ Yamasaki, T; Kojima, H; Tanaka, M; et al. (1981). "Pharmacological studies on timiperone, a new neuroleptic drug Part II: General pharmacological properties". Arzneimittelforschung. 31: 707–15. PMID 6113834.
  3. ^ "Effect of Timiperone, a New Antipsychotic Drug, on the Sleep-Wakefulness Cycle in Cats". The Japanese Journal of Pharmacology. 39 (3): 391–394. 1985.