Perazine

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Perazine
Perazine.svg
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ChEBI
CompTox Dashboard (EPA)
ECHA InfoCard100.001.435 Edit this at Wikidata
Chemical and physical data
FormulaC20H25N3S
Molar mass339.498 g/mol g·mol−1
3D model (JSmol)
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Perazine (Taxilan) is a moderate-potency typical antipsychotic of the phenothiazine class. It is quite similar to chlorpromazine, and acts as a dopamine antagonist. A 2014 systematic review compared it with other antipsychotic drugs:

Perazine versus other antipsychotic drugs for schizophrenia[1]
Summary
The number, size and reporting of randomized controlled perazine trials are insufficient to present firm conclusions about the properties of this antipsychotic. It is possible that perazine is associated with a similar risk of extrapyramidal side effects as some atypical antipsychotics but this is based on few comparisons of limited power.[1]


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External links[edit]

  1. ^ a b Leucht, S; Helfer, B; Hartung, B (2014). "Perazine for schizophrenia". Cochrane Database of Systematic Reviews. 1: CD002832.pub2. doi:10.1002/14651858.CD002832.pub3.