"U and Dat" is the second single from E-40's album My Ghetto Report Card. The song features American singers T-Pain and Kandi Girl, and it was produced by Lil Jon. A remix was released in early August with Juelz Santana, Snoop Dogg, and Lil' Flip. It was featured on an Amp'd Mobile commercial. Although it is considered a West Coast hip hop song, the song's beat structure incorporates typical Southern hip hop dance claps as well as Lil Jon's signature crunk synths and whistles. The song peaked at number 13 on the Billboard Hot 100, which remains E-40's highest-charting single as lead artist to date. The track is credited to have popularized the use of T-Pain as a hook singer on hip hop tracks. The song was certified platinum by the Recording Industry Association of America (RIAA) on March 31, 2016.
The music video is set in a nightclub and within a car. Most of the video includes T-Pain and E-40 scouting various women, Kandi Burruss and Ashalee Albar being just to name a few. Kandi's role in the video is to push off men around her.