Bemiparin sodium

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Bemiparin sodium
Clinical data
AHFS/Drugs.com International Drug Names
Legal status
?
Identifiers
CAS number 91449-79-5 N
ATC code B01AB12
Chemical data
Formula ?
Mol. mass 3600 Daltons (average)
 N (what is this?)  (verify)

Bemiparin is an antithrombotic and belongs to the group of low molecular weight heparins (LMWH).[1]

Like semuloparin, bemiparin is classified as an ultra-LMWH because of its low molecular mass of 3600 Daltons on average.[2] (Enoxaparin has 4500 Daltons.) These heparins have lower anti-thrombin activity than classical LMWHs and act mainly on factor Xa, reducing the risk of bleeding.[3]

References[edit]

  1. ^ Chapman TM, Goa KL (2003). "Bemiparin: a review of its use in the prevention of venous thromboembolism and treatment of deep vein thrombosis". Drugs 63 (21): 2357–77. doi:10.2165/00003495-200363210-00009. PMID 14524738. 
  2. ^ Planès, A. (2003). "Review of bemiparin sodium – a new second-generation low molecular weight heparinand its applications in venous thromboembolism". Expert Opinion on Pharmacotherapy 4 (9): 1551–1561. doi:10.1517/14656566.4.9.1551. PMID 12943485.  edit
  3. ^ Jeske, W. P.; Hoppensteadt, D.; Gray, A.; Walenga, J. M.; Cunanan, J.; Myers, L.; Fareed, J.; Bayol, A.; Rigal, H. L. N.; Viskov, C. (2011). "A common standard is inappropriate for determining the potency of ultra low molecular weight heparins such as semuloparin and bemiparin". Thrombosis Research 128 (4): 361–367. doi:10.1016/j.thromres.2011.03.001. PMID 21458847.  edit