Mooki River at Caroona
|Name origin: Aboriginal: name given to the river by Aboriginal tribes roaming the lower reaches|
|State||New South Wales|
|Region||IBRA: New England Tablelands|
|Part of||Namoi River, Murray–Darling basin|
|Primary source||Liverpool Range|
|- location||south-west of Quirindi|
|- elevation||351 m (1,152 ft)|
|Secondary source||Omaleah Creek and Phillips Creek|
|Mouth||confluence with the Namoi River|
|- location||north-east of Gunnedah|
|- elevation||264 m (866 ft)|
|Length||128 km (80 mi)|
The river rises at the junction of Omaleah Creek and Phillips Creek, and forms below the Liverpool Range, south-west of Quirindi, and flows generally west of north, joined by three minor tributaries, before reaching its confluence with the Namoi River north-east of Gunnedah; descending 88 metres (289 ft) over its 128 kilometres (80 mi) course.
The towns of Quirindi and Werris Creek lie within the basin of the Mooki River, much of which is prime agricultural land. Little natural vegetation remains in the plains but river gums and other trees grow on the banks of the Mooki River. The Kamilaroi Highway and the North-west railway line cross the Mooki River near Breeza.
The earliest recorded exploration of this area is that of John Oxley and his party travelling through here in August 1818. 'Mooki' was the name given to the river by Aboriginal tribes roaming the lower reaches.
Major flooding occurred in and around Gunnedah when the Mooki River flooded in November 2000.