Hiking is a popular activity and the best access method to the Grose River in its upper reaches. There are several well maintained walks that follow scenic sections of the river valley. One of the most popular is through the Blue Gum Forest, located at the junction of the Grose River and Govetts Creek.
The Grose Valley is a rugged valley, formed by the Grose River, the headwaters of which are in the Mount Victoria area. The valley is located between the Great Western Highway and Bells Line of Road, the two major routes across the Blue Mountains. The majority of the valley falls within the Blue Mountains National Park. The valley is popular for bushwalking and contains extensive wilderness areas. The river flows to the Nepean-Hawkesbury through an undisturbed environment for all but its final 5 kilometres (3.1 mi). Consequently the Grose has substantial wild river values, as do its major tributaries such as Wentworth Creek and Carmarthen Brook. The river is known habitat for platypus and certain hanging swamps provide habitat for the endangered and endemic Blue Mountains Water Skink (Eulamprus leuraensis). The rocky sandstone complexes of the plateau provide habitat for some specialised and rare native animal species (e.g. the Broad-headed SnakeHoplocephalus bungaroides). Woodland communities are habitat for mammals such as the Red-necked swamp wallaby, Brush-tailed rock wallaby and Eastern pygmy possum.