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| verifiedrevid = 413604671
| verifiedrevid = 438956231
| IUPAC_name = 3-aminopropyl(diethoxymethyl)phosphinic acid
| IUPAC_name = 3-aminopropyl(diethoxymethyl)phosphinic acid
| image = CGP-35348_structure.png
| image = CGP-35348_structure.png
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| ATC_supplemental =
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| PubChem = 107699
| PubChem = 107699
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank =
| DrugBank =
| chemical_formula =
| chemical_formula =

Revision as of 19:10, 10 September 2011

CGP-35348
Identifiers
  • 3-aminopropyl(diethoxymethyl)phosphinic acid
CAS Number
PubChem CID
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC8H20NO4P
Molar mass225.222 g/mol g·mol−1
3D model (JSmol)
  • CCOC(OCC)P(=O)(CCCN)O
  (verify)

CGP-35348 is a compound used in scientific research which acts as an antagonist at GABAB receptors.[1][2][3]

References

  1. ^ Carter LP, Chen W, Coop A, Koek W, France CP (2006). "Discriminative stimulus effects of GHB and GABA(B) agonists are differentially attenuated by CGP35348". European Journal of Pharmacology. 538 (1–3): 85–93. doi:10.1016/j.ejphar.2006.03.039. PMID 16647701. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  2. ^ Nasrallah FA, Griffin JL, Balcar VJ, Rae C (2007). "Understanding your inhibitions: modulation of brain cortical metabolism by GABA(B) receptors". Journal of Cerebral Blood Flow and Metabolism. 27 (8): 1510–20. doi:10.1038/sj.jcbfm.9600453. PMID 17293844. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  3. ^ Koek W, Mercer SL, Coop A, France CP (2009). "Behavioral effects of gamma-hydroxybutyrate, its precursor gamma-butyrolactone, and GABA(B) receptor agonists: time course and differential antagonism by the GABA(B) receptor antagonist 3-aminopropyl(diethoxymethyl)phosphinic acid (CGP35348)". The Journal of Pharmacology and Experimental Therapeutics. 330 (3): 876–83. doi:10.1124/jpet.109.151845. PMID 19564487. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)