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[[Image:Traumatic ulcerative granuloma with stromal eosinophils - alt -- extremely low mag.jpg|thumb|right|Eosinophilic ulcer of the oral mucosa. [[H&E stain]].]]
'''Eosinophilic ulcer of the oral mucosa''' (also known as "Eosinophilic ulcer of the tongue,"<ref name="Bolognia" /> "[[Riga–Fede disease]],"<ref name="Bolognia" /> and "Traumatic eosinophilic granuloma"<ref name="Bolognia">{{cite book |author1=Rapini, Ronald P. |author2=Bolognia, Jean L. |author3=Jorizzo, Joseph L. |title=Dermatology: 2-Volume Set |publisher=Mosby |location=St. Louis |year=2007 |pages= |isbn=1-4160-2999-0 |oclc= |doi= |accessdate=}}</ref>) is a condition characterized by an ulcer with an [[induration|indurated]] and elevated border.<ref name="Andrews">{{cite book |author=James, William D. |title=Andrews' Diseases of the Skin: Clinical Dermatology |publisher=Saunders Elsevier |location= |year=2006 |pages= |isbn=0-7216-2921-0 |oclc= |doi= |accessdate= |last2=Berger |first2=Timothy G. }}</ref>{{rp|803}} The lesion might be tender, fast-growing and the patient often not be aware of any trauma in the area.
'''Eosinophilic ulcer of the oral mucosa''' (also known as '''eosinophilic ulcer of the tongue''',<ref name="Bolognia" /> '''[[Riga–Fede disease]]''',<ref name="Bolognia" /> and '''traumatic eosinophilic granuloma'''<ref name="Bolognia">{{cite book |author1=Rapini, Ronald P. |author2=Bolognia, Jean L. |author3=Jorizzo, Joseph L. |title=Dermatology: 2-Volume Set |publisher=Mosby |location=St. Louis |year=2007 |pages= |isbn=1-4160-2999-0 |oclc= |doi= |accessdate=}}</ref>) is a condition characterized by an ulcer with an [[induration|indurated]] and elevated border.<ref name="Andrews">{{cite book |author=James, William D. |title=Andrews' Diseases of the Skin: Clinical Dermatology |publisher=Saunders Elsevier |location= |year=2006 |pages= |isbn=0-7216-2921-0 |oclc= |doi= |accessdate= |last2=Berger |first2=Timothy G. }}</ref>{{rp|803}} The lesion might be tender, fast-growing and the patient often not be aware of any trauma in the area.


==Definition==
==Definition==

Revision as of 04:48, 5 January 2017

Eosinophilic ulcer of the oral mucosa. H&E stain.

Eosinophilic ulcer of the oral mucosa (also known as eosinophilic ulcer of the tongue,[1] Riga–Fede disease,[1] and traumatic eosinophilic granuloma[1]) is a condition characterized by an ulcer with an indurated and elevated border.[2]: 803  The lesion might be tender, fast-growing and the patient often not be aware of any trauma in the area.

Definition

Traumatic eosinophilic granuloma of the tongue (TEGT) is a reactive condition that commonly occurs on the ventral tongue.

Causes

It is often associated with trauma. However, other causes are suspected, such as drugs, inherent predisposition, immune reaction, or lymphoproliferative disorder.

Differential Diagnosis

Squamouce Cell Carcinoma, Pyogenic granulomas, Lesions of a chronic granulomatous disease and Mesenchymal tumors

Treatment

When the lesion is excised, recurrence often occurs. Palliative care with nonsteroidal anti-inflammatory drugs (NSAIDs) may be used, and topical steroids can be curative. If the lesion does not respond to treatment, biopsy is required.

See also

References

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  1. ^ a b c Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0.
  2. ^ James, William D.; Berger, Timothy G. (2006). Andrews' Diseases of the Skin: Clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.

3. Ficarra G, Prignano F, Romagnoli P. Traumatic eosinophilic granuloma of the oral mucosa: A lymphoproliferative disorder? Oral Oncol.1997;33(5):375-379.