Streptococcus
| Streptococcus | |
|---|---|
| |
| Scientific classification | |
| Kingdom: | |
| Phylum: | |
| Class: | |
| Order: | |
| Family: | |
| Genus: | Streptococcus Rosenbach, 1884
|
| Species | |
|
S. agalactiae | |
Streptococcus is a genus of spherical Gram-positive bacteria belonging to the phylum Firmicutes[2] and the lactic acid bacteria group. Cellular division occurs along a single axis in these bacteria, and thus they grow in chains or pairs, hence the name — from Greek στρεπτος streptos, meaning easily bent or twisted, like a chain (twisted chain). Contrast this with staphylococci, which divide along multiple axes and generate grape-like clusters of cells. Streptococci are oxidase- and catalase-negative, and many are facultative anaerobes.
In 1984, many organisms formerly considered Streptococcus were separated out into the genera Enterococcus and Lactococcus.[3]
=
Alpha-hemolytic
Pneumococci
- S. pneumoniae, a leading cause of bacterial pneumonia and occasional etiology of otitis media, sinusitis, meningitis and peritonitis.
The Viridans group: alpha hemolytic
- S. mutans, a contributor to dental caries
- S. mitis, mostly found around cheek region
- S. sanguinis, no preference of locations
- S. salivarius, mostly found on the dorsal side of the tongue
- S. salivarius ssp. thermophilus, used in the manufacture of some cheeses and yogurts
- S. constellatus, occasional human pathogen, notable as colonies grown on blood agar smell strongly of caramel
Beta-hemolytic
Group A
S. pyogenes, also known as Group A Streptococcus (GAS), is the causative agent in Group A streptococcal infections, including streptococcal pharyngitis ("strep throat" AmE), acute rheumatic fever, scarlet fever, acute glomerulonephritis and necrotizing fasciitis. If strep throat is not treated, it can develop into rheumatic fever, a disease that affects the joints and heart valves. Other Streptococcus species may also possess the Group A antigen, but human infections by non-S. pyogenes GAS strains (some S. dysgalactiae subsp. equisimilis and S. anginosus Group strains) appear to be uncommon.
Group A Streptococcus infection is generally diagnosed with a Rapid Strep Test (AmE) or by culture.
Group B
S. agalactiae, or GBS, causes pneumonia and meningitis in neonates and the elderly, with occasional systemic bacteremia. They can also colonize the intestines and the female reproductive tract, increasing the risk for premature rupture of membranes and transmission to the infant. The American College of Obstetricians and Gynecologists, American Academy of Pediatrics and the Centers for Disease Control recommend all pregnant women between 35 and 37 weeks gestation should be tested for GBS. Women who test positive should be given prophylactic antibiotics during labor, which will usually prevent transmission to the infant.[4] In the UK, clinicians have been slow to implement the same standards as the US, Australia and Canada. In the UK, only 1% of maternity units test for the presence of Group B Streptococcus.[5] Although The Royal College of Obstetricians and Gynaecologists issued risk-based guidelines in 2003 (due for review 2006), the implementation of these guidelines has been patchy. Some groups feel that as a result over 75 infants in the UK die each year of GBS related disease and another 600 or so suffer serious infection, most of which could be prevented [6] however this is yet to be substantiated by randomized controlled trial in the UK setting and, given the evidence for the efficacy of testing and treating from other countries, it may be that the large-scale trial necessary would receive neither funding nor ethics approval.[7]
Group C
Includes S. equi, which causes strangles in horses,[8] and S. zooepidemicus - S. equi is a clonal descendent or biovar of the ancestral S. zooepidemicus - which causes infections in several species of mammals including cattle and horses.
The Group D strains include Streptococcus bovis and Streptococcus equinus.
Group G streptococci
These streptococci are usually but not exclusively beta hemolytic. Streptococcus canis is an example of a GGS which is typically found on animals but can cause infection in humans.
Non-hemolytic
Group D (enterococci)
Many former Group D streptococci have been reclassified and placed in the genus Enterococcus (including S. faecalis, S. faecium, S. durans, and S. avium).[9] For example, Streptococcus faecalis is now Enterococcus faecalis.
The remaining non-enterococcal Group D strains include Streptococcus bovis and Streptococcus equinus.
Non-hemolytic streptococci rarely cause illness. However, weakly hemolytic group D beta-hemolytic streptococci and Listeria monocytogenes (which is actually a gram positive bacillus) should not be confused with non-hemolytic streptococci.
Treatment
- See List of antibiotics.
See also
References
- ^ "Result of detail taxonomy information". TXSearch Taxonomy Retrieval. DNA Data Bank of Japan. 19 February 2010. Retrieved 30 March 2010.
- ^ Sherris Medical Microbiology (4th ed.). McGraw Hill. 2004. ISBN 0-8385-8529-9.
{{cite book}}: Unknown parameter|editors=ignored (|editor=suggested) (help) - ^ Facklam R (2002). "What happened to the streptococci: overview of taxonomic and nomenclature changes". Clin. Microbiol. Rev. 15 (4): 613–30. doi:10.1128/CMR.15.4.613-630.2002. PMC 126867. PMID 12364372.
{{cite journal}}: Unknown parameter|month=ignored (help) - ^ Schrag S, Gorwitz R, Fultz-Butts K, Schuchat A (2002). "Prevention of perinatal group B streptococcal disease. Revised guidelines from CDC". MMWR Recomm Rep. 51 (RR-11): 1–22. PMID 12211284.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ Hughes, RG; et al. "Prevention of Early Onset Neonatal Group B Streptococcal Disease". Royal College of Obstetricians and Gynaecologists.
{{cite journal}}: Cite journal requires|journal=(help); Explicit use of et al. in:|author=(help) - ^ "Group B Strep Support Home Page". Group B Strep Support. 2007-01-09.
- ^ "RCOG: Preventing group B streptococcus infection in new born babies". RCOG. 2006-02.
{{cite web}}: Check date values in:|date=(help) - ^ Harrington D, Sutcliffe I, Chanter N (2002). "The molecular basis of Streptococcus equi infection and disease". Microbes Infect. 4 (4): 501–10. doi:10.1016/S1286-4579(02)01565-4. PMID 11932201.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ Ruoff KL (1990). "Recent taxonomic changes in the genus Enterococcus". Eur J Clin Microbiol Infect Dis. 9 (2): 75–9. doi:10.1007/BF01963630. PMID 2108030.
External links
- Streptococcus genomes and related information at PATRIC, a Bioinformatics Resource Center funded by NIAID
- Prevention of Perinatal Group B Streptococcal Disease August 16, 2002 MMWR 2000;49:228-232.
- The Canadian Strep B Foundation
- The UK Group B Strep Support charity