3-Methyluridine

3-Methyluridine
Names
	IUPAC name 3-Methyluridine
	Preferred IUPAC name 1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3-methylpyrimidine-2,4(1H,3H)-dione
	Other names N3-Methyluridine; N-3-Methyluridine
Identifiers
CAS Number	2140-69-4;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:89487;
ChemSpider	29272117;
PubChem CID	99592;
CompTox Dashboard (EPA)	DTXSID201316911 ;
	InChI InChI=1S/C10H14N2O6/c1-11-6(14)2-3-12(10(11)17)9-8(16)7(15)5(4-13)18-9/h2-3,5,7-9,13,15-16H,4H2,1H3/t5-,7-,8-,9-/m1/s1 Key: UTQUILVPBZEHTK-ZOQUXTDFSA-N;
	SMILES CN1C(=O)C=CN(C1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O;
Properties
Chemical formula	C10H14N2O6
Molar mass	258.230 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

The chemical compound 3-methyluridine, also called N3-methyluridine, is a pyrimidine nucleoside (abbreviated m3U). In living organisms it is present as RNA modification which has been detected in 23S rRNA of archaea, 16S and 23S rRNA of eubacteria, and 18S, 25S, and 28S of eukaryotic ribosomal RNAs.^[1]

References

^ Desaulniers, Jean-Paul; Chui, Helen M.-P.; Chow, Christine S. (2005-12-15). "Solution conformations of two naturally occurring RNA nucleosides: 3-methyluridine and 3-methylpseudouridine". Bioorganic & Medicinal Chemistry. 13 (24): 6777–6781. doi:10.1016/j.bmc.2005.07.061. ISSN 0968-0896. PMID 16125393.

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[1] Desaulniers, Jean-Paul; Chui, Helen M.-P.; Chow, Christine S. (2005-12-15). "Solution conformations of two naturally occurring RNA nucleosides: 3-methyluridine and 3-methylpseudouridine". Bioorganic & Medicinal Chemistry. 13 (24): 6777–6781. doi:10.1016/j.bmc.2005.07.061. ISSN 0968-0896. PMID 16125393.

[1]

See also

References