Isepamicin

Isepamicin
Clinical data
Other names	(2S)-3-Amino-N-[(1R,2S,3S,4R,5S)-5-amino-4-[(3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy-2-[(3R,4R,5R)-3,5-dihydroxy-5-methyl-4-methylaminooxan-2-yl]oxy-3-hydroxycyclohexyl]-2-hydroxypropanamide
AHFS/Drugs.com	International Drug Names
ATC code	J01GB11 (WHO) ;
Identifiers
	IUPAC name (2S)-3-amino-N-((1R,2S,3S,4R,5S)-5-amino-4-[(6-amino-6-deoxy-D-glucopyranosyl)oxy]-2-{[3-deoxy-4-C-methyl-3-(methylamino)-L-arabinopyranosyl]oxy}-3-hydroxycyclohexyl)-2-hydroxypropanamide;
CAS Number	58152-03-7 ;
PubChem CID	3037209;
ChemSpider	2301019 ;
UNII	G7K224460P;
ChEMBL	ChEMBL272080 ;
CompTox Dashboard (EPA)	DTXSID1048380 ;
ECHA InfoCard	100.055.567
Chemical and physical data
Formula	C22H43N5O12
Molar mass	569.609 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C[C@@]1(CO[C@@H]([C@@H]([C@H]1NC)O)O[C@H]2[C@@H](C[C@@H]([C@H]([C@@H]2O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CN)O)O)O)N)NC(=O)[C@H](CN)O)O;
	InChI InChI=1S/C22H43N5O12/c1-22(35)6-36-20(15(33)18(22)26-2)39-17-8(27-19(34)9(28)4-23)3-7(25)16(14(17)32)38-21-13(31)12(30)11(29)10(5-24)37-21/h7-18,20-21,26,28-33,35H,3-6,23-25H2,1-2H3,(H,27,34)/t7-,8+,9-,10+,11+,12-,13+,14-,15+,16+,17-,18+,20+,21+,22-/m0/s1 ; Key:UDIIBEDMEYAVNG-ZKFPOVNWSA-N ;
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Isepamicin (also Isepamycin) is an aminoglycoside antibiotic.

It was patented in 1973 and approved for medical use in 1988.^[1] It has been identified by the World Health Organization as a Critically Important Antimicrobial for human use.^[2]

References

^ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 508. ISBN 9783527607495.
^ "Critically important antimicrobials for human medicine" (PDF). World Health Organization. 2012.

This systemic antibiotic-related article is a stub. You can help Wikipedia by expanding it.

[Fis2006-1] Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 508. ISBN 9783527607495.

[2] "Critically important antimicrobials for human medicine" (PDF). World Health Organization. 2012.

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