Jump to content

Psoralen synthase

From Wikipedia, the free encyclopedia

This is an old revision of this page, as edited by BrownHairedGirl (talk | contribs) at 15:11, 29 September 2019 (replace links to deleted portals: Portal:Molecular and Cellular BiologyPortal:Biology). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Psoralen synthase
Identifiers
EC no.1.14.13.102
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a psoralen synthase (EC 1.14.13.102) is an enzyme that catalyzes the chemical reaction

(+)-marmesin + NADPH + H+ + O2 psoralen + NADP+ + acetone + 2 H2O

The 4 substrates of this enzyme are (+)-marmesin, NADPH, H+, and O2, whereas its 4 products are psoralen, NADP+, acetone, and H2O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and incorporation of one atom o oxygen into the other donor. The systematic name of this enzyme class is (?). This enzyme is also called CYP71AJ1.

References

  • Larbat R, Kellner S, Specker S, Hehn A, Gontier E, Hans J, Bourgaud F, Matern U (January 2007). "Molecular cloning and functional characterization of psoralen synthase, the first committed monooxygenase of furanocoumarin biosynthesis" (PDF). The Journal of Biological Chemistry. 282 (1): 542–54. doi:10.1074/jbc.M604762200. PMID 17068340.{{cite journal}}: CS1 maint: unflagged free DOI (link)