Ilepcimide

Ilepcimide
Clinical data
ATC code	none;
Identifiers
	IUPAC name (2E)-3-(2H-1,3-Benzodioxol-5-yl)-1-(piperidin-1-yl)prop-2-en-1-one;
CAS Number	23434-86-8 ;
PubChem CID	641115;
ChemSpider	556435 ;
UNII	5ML58O200F;
Chemical and physical data
Formula	C15H17NO3
Molar mass	259.305 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1CCN(CC1)C(=O)/C=C/C2=CC3=C(C=C2)OCO3;
	InChI InChI=1S/C15H17NO3/c17-15(16-8-2-1-3-9-16)7-5-12-4-6-13-14(10-12)19-11-18-13/h4-7,10H,1-3,8-9,11H2/b7-5+ ; Key:BLPUOQGPBJPXRL-FNORWQNLSA-N ;
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Ilepcimide, also known as antiepilepserine, is an anticonvulsant.^[1] It is a piperidine derivative that was first synthesized by Chinese researchers as an analogue of piperine, the main alkaloid and phytochemical of black pepper (and of other plants in the family Piperaceae).

Ilepcimide has serotonergic activity.^[1]^[2]^[3]

References

^ ^a ^b C.R. Ganellin; David J. Triggle (21 November 1996). Dictionary of Pharmacological Agents. CRC Press. p. 1116. ISBN 978-0-412-46630-4. Retrieved 30 November 2012.
^ Liu, G.Q., Algeria, S., Ceci, A., Gerattini, S., Gobi, M. and Murai, S. (1984). "Stimulation of serotonin synthesis in rat brain after antiepilepserine, an antiepileptic piperine derivative". Biochemical Pharmacology. 33: 3883–3886. doi:10.1016/0006-2952(84)90055-8.{{cite journal}}: CS1 maint: multiple names: authors list (link)
^ Yan, Q.S., Mishra, P.K., Burger, R.L., Bettendorf, A.F., Jobe, P.C. and Dailey J.W. (1992). "Evidence that carbamazepine and antiepilepserine may produce a component of their anticonvulsant effects by activating serotonergic neurons in genetically epilepsy-prone rats". J. Pharmacol. Exp. Ther. 261 (2): 652–659.{{cite journal}}: CS1 maint: multiple names: authors list (link)

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