KMUP-1
Appearance
Names | |
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IUPAC name
7-[2-[4-(2-Chlorophenyl)piperazin-1-yl]ethyl]-1,3-dimethylpurine-2,6-dione
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Other names
7-[2-[4-(2-Chlorophenyl)piperazinyl]ethyl]-1,3-dimethylxanthine
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Identifiers | |
3D model (JSmol)
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ChemSpider | |
ECHA InfoCard | 100.211.655 |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C19H23ClN6O2 | |
Molar mass | 402.88 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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KMUP-1 is a xanthine derivative with phosphodiesterase inhibitor activity.[1]
References
- ^ "KMUP-1 suppresses RANKL-induced osteoclastogenesis and prevents ovariectomy-induced bone loss: roles of MAPKs, Akt, NF-κB and calcium/calcineurin/NFATc1 pathways". PLoS ONE. 8 (7): e69468. 2013. doi:10.1371/journal.pone.0069468. PMC 3723916. PMID 23936022.
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: CS1 maint: unflagged free DOI (link)