Diprophylline

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Diprophylline
Diprophylline.svg
Clinical data
Trade names Lufyllin
AHFS/Drugs.com Consumer Drug Information
MedlinePlus a682494
Pregnancy
category
  • US: C (Risk not ruled out)
Routes of
administration
By mouth
ATC code
Legal status
Legal status
Identifiers
Synonyms 7-(2,3-Dihydroxy-propyl)theophylline
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
ECHA InfoCard 100.006.843
Chemical and physical data
Formula C10H14N4O4
Molar mass 254.24 g/mol
3D model (JSmol)
  (verify)

Diprophylline (INN)[1] or dyphylline (USAN) (trade names Dilor, Lufyllin), is a xanthine derivative with bronchodilator and vasodilator effects. It is used in the treatment of respiratory disorders like asthma, cardiac dyspnea, and bronchitis. It acts as an adenosine receptor antagonist and phosphodiesterase inhibitor.[2][3]

See also[edit]

References[edit]

  1. ^ "International Non-Proprietary Names. Recommended International Non-Proprietary Names (Rec. I.N.N.): List 1" (PDF). World Health Organization. 1955. p. 188. 
  2. ^ Schwabe, U; Ukena, D; Lohse, MJ (September 1985). "Xanthine Derivatives as Antagonists at A1 and A2 Adenosine Receptors". Naunyn-Schmiedeberg's Archives of Pharmacology. 330 (3): 212–21. PMID 2997628. doi:10.1007/bf00572436. 
  3. ^ Iancu, L; Shneur, A; Cohen, H (1979). "Trials with Xanthine Derivatives in Systemic Treatment of Psoriasis". Dermatologica. 159 (1): 55–61. PMID 225216. doi:10.1159/000250562.