ADCY1

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ADCY1
Identifiers
Aliases ADCY1, AC1, DFNB44, adenylate cyclase 1 (brain)
External IDs MGI: 99677 HomoloGene: 41419 GeneCards: ADCY1
RNA expression pattern
PBB GE ADCY1 215348 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001281768
NM_021116

NM_009622

RefSeq (protein)

NP_001268697
NP_066939

NP_033752.1
NP_033752

Location (UCSC) Chr 7: 45.57 – 45.72 Mb Chr 11: 7.06 – 7.18 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Adenylyl cyclase type 1 is an enzyme that in humans is encoded by the ADCY1 gene.[3][4]

This gene encodes a form of adenylyl cyclase expressed in brain. A similar protein in mice is involved in pattern formation of the brain.[4]

Function[edit]

ADCY1 is a calmodulin-sensitive adenylyl cyclase. In terms of function, It may be involved in regulatory processes in the central nervous system; specifically, it may play a role in memory acquisition and learning. It is inhibited by the G protein beta and gamma subunit complex.[5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Villacres EC, Xia Z, Bookbinder LH, Edelhoff S, Disteche CM, Storm DR (May 1993). "Cloning, chromosomal mapping, and expression of human fetal brain type I adenylyl cyclase". Genomics. 16 (2): 473–8. doi:10.1006/geno.1993.1213. PMID 8314585. 
  4. ^ a b "Entrez Gene: ADCY1 adenylyl cyclase 1 (brain)". 
  5. ^ "Gene Cards: ADCY1 Gene". Retrieved 2012-12-30. 

External links[edit]

Further reading[edit]