Jump to content

Calpain small subunit 1

From Wikipedia, the free encyclopedia

This is an old revision of this page, as edited by Mssewalim (talk | contribs) at 20:47, 23 September 2018. The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Calpain small subunit 1
Identifiers
Aliases
External IDsGeneCards: [1]; OMA:- orthologs
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n
a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Calpain small subunit 1, also known as CAPN4, is a protein that in humans is encoded by the CAPNS1 gene.[1][2][3]

Template:PBB Summary

Functions

Myotonic dystrophy

This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy.[3]

Biomarker

Elevated expression of Capn4 has been found to be associated with progression of various cancers such as hepatocellular and renal carcinoma. [4]

References

  1. ^ Miyake S, Emori Y, Suzuki K (Jan 1987). "Gene organization of the small subunit of human calcium-activated neutral protease". Nucleic Acids Res. 14 (22): 8805–17. doi:10.1093/nar/14.22.8805. PMC 311912. PMID 3024120.
  2. ^ Ohno S, Emori Y, Suzuki K (Sep 1986). "Nucleotide sequence of a cDNA coding for the small subunit of human calcium-dependent protease". Nucleic Acids Res. 14 (13): 5559. PMC 311560. PMID 3016651.
  3. ^ a b "Entrez Gene: CAPNS1 calpain, small subunit 1".
  4. ^ Zhuang Q (Apr 2014). "Capn4 mRNA level is correlated with tumour progression and clinical outcome in clear cell renal cell carcinoma". J Int Med Res. 42: 282–91. doi:10.1177/0300060513505524. PMID 24514433.

Further reading

Template:PBB Further reading

Template:PBB Controls


Stub icon

This article on a gene on human chromosome 19 is a stub. You can help Wikipedia by expanding it.

Retrieved from "https://en.wikipedia.org/w/index.php?title=Calpain_small_subunit_1&oldid=860899974"