Haplogroup L4a (mtDNA)

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Haplogroup L4a
Possible place of origin Africa
Ancestor L4
Descendants L4a
Defining mutations 195C, 3357, 5460, 10373, 11253, 11344, 11485, 12414, 13174, 14302, 16260

In human genetics, Haplogroup L4a is a human mitochondrial DNA (mtDNA) haplogroup. It is a small African haplogroup.[1] It was once called L7 and considered its own branch of L. It was determined to be a subclade of L4 and renamed L4a by Behar et al. in The dawn of human matrilineal diversity.[2]

Origin[edit]

Distribution[edit]

Tree[edit]

This phylogenetic tree of haplogroup L4a subclades is based on the paper by Mannis van Oven and Manfred Kayser Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation[3] and subsequent published research.

    • L4
      • L4a
        • L4a1
          • L4a1a
        • L4a2

See also[edit]

Phylogenetic tree of human mitochondrial DNA (mtDNA) haplogroups

  Mitochondrial Eve (L)    
L0 L1–6
L1 L2 L3   L4 L5 L6
  M   N  
CZ D E G Q   O A S   R   I W X Y
C Z B F R0   pre-JT P  U
HV JT K
H V J T

References[edit]

  1. ^ Haplogroups L7.
  2. ^ Behar, M.; Villems, R.; Soodyall, H.; Blue-Smith, J.; Pereira, L.; Metspalu, E.; Scozzari, R.; Makkan, H.; Tzur, S.; Comas, D.; Bertranpetit, J.; Quintana-Murci, L.; Tyler-Smith, C.; Wells, R. S.; Rosset, S.; Genographic, C. (May 2008). "The Dawn of Human Matrilineal Diversity". American Journal of Human Genetics. 82 (5): 1130–1140. doi:10.1016/j.ajhg.2008.04.002. ISSN 0002-9297. PMC 2427203Freely accessible. PMID 18439549. 
  3. ^ Van Oven, Mannis; Kayser, Manfred (February 2009). "Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation". Human Mutation. 30 (2): E386–94. doi:10.1002/humu.20921. PMID 18853457. Retrieved 2009-05-20. 

External links[edit]