As of 2010, the city has an estimated population of 128,034 and a population density of 10,430 persons per km². The total area is 12.28 km².
Kadoma is located northeast of Osaka on the Keihan Railway, and is connected to Osaka's other northern suburbs by the Osaka Monorail. The city is well-known within Japan as being the site of the headquarters of Matsushita (National/Panasonic).
In 2005, it was planned to merge Kadoma with the neighboring city of Moriguchi, however the plan was cancelled.