Kallistatin

SERPINA4
Identifiers
Aliases	SERPINA4, KAL, KLST, KST, PI-4, PI4, kallistatin, serpin family A member 4
External IDs	OMIM: 147935; HomoloGene: 48412; GeneCards: SERPINA4; OMA:SERPINA4 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	94,569,913 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; body of pancreas; ; gallbladder; ; islet of Langerhans; ; corpus epididymis; ; caput epididymis; ; body of stomach; ; seminal vesicula; ; tail of epididymis; ; tibialis anterior muscle;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	peptidase inhibitor activity; serine-type endopeptidase inhibitor activity;
Cellular component	extracellular exosome; platelet dense granule lumen; extracellular space; extracellular region;
Biological process	negative regulation of peptidase activity; platelet degranulation; negative regulation of endopeptidase activity;
	Sources:Amigo / QuickGO
Orthologs
	5267
	n/a
	ENSG00000100665
	n/a
	P29622
	n/a
	NM_006215; NM_001289032; NM_001289033
	n/a
	NP_001275961; NP_001275962; NP_006206
	n/a
	Wikidata
View/Edit Human

Kallistatin is a protein that in humans is encoded by the SERPINA4 gene.^[3]^[4]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000100665 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Chai KX, Chen LM, Chao J, Chao L (Dec 1993). "Kallistatin: a novel human serine proteinase inhibitor. Molecular cloning, tissue distribution, and expression in Escherichia coli". J Biol Chem. 268 (32): 24498–505. PMID 8227002.
^ "Entrez Gene: SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4".

The MEROPS online database for peptidases and their inhibitors: I04.003
SERPINA4+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article on a gene on human chromosome 14 is a stub. You can help Wikipedia by expanding it.

v t e Serpins
inhibitory	Alpha 1-antichymotrypsin Alpha 1-antitrypsin Alpha 2-antiplasmin Antithrombin C1-inhibitor Heparin cofactor II Protein C inhibitor Plasminogen activator inhibitor-1 Plasminogen activator inhibitor-2 Protein Z-related protease inhibitor SERPINA1 SERPINA2 SERPINA3 SERPINA4 SERPINA5 SERPINA9 SERPINA14 SERPINB1 SERPINB2 SERPINB3 SERPINB4 SERPINB5 SERPINB6 SERPINB7 SERPINB8 SERPINB9 SERPINB10 SERPINB13 SERPINC1 SERPIND1 SERPINE1 SERPINE2 SERPINE2 SERPINF1 SERPING1 SERPINH1 SERPINI1 SERPINI2
Cross class inhibitory	MENT SCCA-1 CrmA
noninhibitory	Heat shock protein 47 Maspin Ovalbumin Transcortin Thyroxine-binding globulin Angiotensinogen PEDF
see also disorders of globin and globulin proteins