SERPINB13

SERPINB13
Identifiers
Aliases	SERPINB13, HSHUR7SEQ, HUR7, PI13, headpin, serpin family B member 13
External IDs	OMIM: 604445; MGI: 3042250; HomoloGene: 22718; GeneCards: SERPINB13; OMA:SERPINB13 - orthologs
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	106,928,925 bp
RNA expression pattern
	n/a
	Top expressed in
	esophagus; ; lip; ; zone of skin; ; stomach;
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	peptidase inhibitor activity; protease binding; cysteine-type endopeptidase inhibitor activity; serine-type endopeptidase inhibitor activity;
Cellular component	cytoplasm; extracellular exosome; nucleolus; nucleoplasm; extracellular space; cytosol; nuclear speck; lysosomal lumen;
Biological process	negative regulation of peptidase activity; response to UV; regulation of proteolysis; negative regulation of endopeptidase activity; negative regulation of keratinocyte apoptotic process; regulation of keratinocyte differentiation;
	Sources:Amigo / QuickGO
Orthologs
	5275
	241196
	ENSG00000197641
	ENSMUSG00000048775
	Q9UIV8
	Q8CDC0
	NM_001307923; NM_012397
	NM_172852
NP_001294852; NP_036529; NP_001335196; NP_001335197; NP_001335198;
	NP_001335199
	NP_766440
	Wikidata
View/Edit Human	View/Edit Mouse

Serpin B13 is a protein that in humans is encoded by the SERPINB13 gene.^[4]^[5]^[6]

References

^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000048775 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Abts HF, Breuhahn K, Michel G, Kohrer K, Esser P, Ruzicka T (Oct 1997). "Analysis of UVB-modulated gene expression in human keratinocytes by mRNA differential display polymerase chain reaction". Photochem Photobiol. 66 (3): 363–7. doi:10.1111/j.1751-1097.1997.tb03159.x. PMID 9297979.
^ Abts HF, Welss T, Mirmohammadsadegh A, Kohrer K, Michel G, Ruzicka T (Nov 1999). "Cloning and characterization of hurpin (protease inhibitor 13): A new skin-specific, UV-repressible serine proteinase inhibitor of the ovalbumin serpin family". J Mol Biol. 293 (1): 29–39. doi:10.1006/jmbi.1999.3159. PMID 10512713.
^ "Entrez Gene: SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13".

The MEROPS online database for peptidases and their inhibitors: I04.017
SERPINB13+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 18 is a stub. You can help Wikipedia by expanding it.

v t e Serpins
inhibitory	Alpha 1-antichymotrypsin Alpha 1-antitrypsin Alpha 2-antiplasmin Antithrombin C1-inhibitor Heparin cofactor II Protein C inhibitor Plasminogen activator inhibitor-1 Plasminogen activator inhibitor-2 Protein Z-related protease inhibitor SERPINA1 SERPINA2 SERPINA3 SERPINA4 SERPINA5 SERPINA9 SERPINA14 SERPINB1 SERPINB2 SERPINB3 SERPINB4 SERPINB5 SERPINB6 SERPINB7 SERPINB8 SERPINB9 SERPINB10 SERPINB13 SERPINC1 SERPIND1 SERPINE1 SERPINE2 SERPINE2 SERPINF1 SERPING1 SERPINH1 SERPINI1 SERPINI2
Cross class inhibitory	MENT SCCA-1 CrmA
noninhibitory	Heat shock protein 47 Maspin Ovalbumin Transcortin Thyroxine-binding globulin Angiotensinogen PEDF
see also disorders of globin and globulin proteins