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SNX21

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SNX21
Identifiers
AliasesSNX21, C20orf161, PP3993, SNX-L, dJ337O18.4, sorting nexin family member 21, SNXL
External IDsMGI: 1917729; HomoloGene: 43132; GeneCards: SNX21; OMA:SNX21 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001042632
NM_001042633
NM_033421
NM_152897

NM_133924
NM_001399716

RefSeq (protein)

NP_001036097
NP_001036098
NP_219489
NP_690857

NP_598685
NP_001386645

Location (UCSC)Chr 20: 45.83 – 45.84 MbChr 2: 164.63 – 164.64 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Sorting nexin-21 is a protein that in humans is encoded by the SNX21 gene.[5][6][7]

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members. The specific function of this protein has not been determined. Multiple transcript variants encoding distinct isoforms have been identified for this gene.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000124104Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000050373Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Worby CA, Dixon JE (Dec 2002). "Sorting out the cellular functions of sorting nexins". Nat Rev Mol Cell Biol. 3 (12): 919–31. doi:10.1038/nrm974. PMID 12461558. S2CID 36361630.
  6. ^ Zeng W, Yuan W, Wang Y, Jiao W, Zhu Y, Huang C, Li D, Li Y, Zhu C, Wu X, Liu M (Dec 2002). "Expression of a novel member of sorting nexin gene family, SNX-L, in human liver development". Biochem Biophys Res Commun. 299 (4): 542–8. doi:10.1016/S0006-291X(02)02695-5. PMID 12459172.
  7. ^ a b "Entrez Gene: SNX21 sorting nexin family member 21".

Further reading

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