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SNX27

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SNX27
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSNX27, MRT1, MY014, sorting nexin family member 27, sorting nexin 27
External IDsOMIM: 611541; MGI: 1923992; HomoloGene: 12797; GeneCards: SNX27; OMA:SNX27 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_030918
NM_001330723

NM_001082484
NM_029721

RefSeq (protein)

NP_001317652
NP_112180

NP_001075953
NP_083997

Location (UCSC)Chr 1: 151.61 – 151.7 MbChr 3: 94.4 – 94.49 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Sorting nexin family member 27, also known as SNX27, is a human gene.[5]

This gene encodes a member of the sorting nexin family, a diverse group of cytoplasmic and membrane-associated proteins involved in endocytosis of plasma membrane receptors and protein trafficking through these compartments. All members of this protein family contain a phosphoinositide binding domain (PX domain). A highly similar protein in mice is responsible for the specific recruitment of an isoform of the serotonin 5-hydroxytryptamine 4 receptor into early endosomes, suggesting the analogous role for the human protein.[5]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000143376Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028136Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: SNX27 sorting nexin family member 27".

Further reading

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