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User:David Hedlund

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— Wikipedian  —
Name in real life David Hedlund
Nationality Sweden
Country  Sweden
Languages Native Swedish. Basic knowledge of English.
Time zone UTC+01:00
Ethnicity Sweden
Race White
Account statistics
Joined 2009-09-25T20:41:42
Additional information
Committed identity


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User:UBX/create userbox

Crypto key.svg This user has committed identity.
See this userbox's invocation.
Symbol support vote.svg This user has contributed to 0 Good Articles on Wikipedia.
Quality, not quantity. This user believes that a user's edit count does not necessarily reflect on the value of their contributions to Wikipedia.
6028 This user is ranked 6028 on the list of Wikipedians by number of edits.
Babel user information
en-1 This user has basic knowledge of English.
sv-N Den här användaren har svenska som modersmål.
Users by language
Wikipedia-logo.png This user has been a member of Wikipedia since 25 September 2009.
Flag of Sweden.svg This user is a citizen of Sweden
Klok.svg It is approximately 9:57 AM in this user's locale. (Purge to update.)
{{Wiki}} This user is just starting to learn to write in the MediaWiki language.
wiki-2 This user is an intermediate Wikipedia editor.
HTML-3 This user is an advanced HTML user.
Mandelbrot sequence small.gif Go slowly insane as you sit and stare...

Amanita Muscaria (scaled).jpg This user contributes to the WikiProject Psychoactive and Recreational Drugs.

C2H5OH This user believes alcohol is dangerous, and as such does not drink it. However, if this user does not believe alcohol is dangerous, this user absolutely hates alcohol.
Anticannabis.jpg This user abstains from
all forms of cannabis.
DIN 4844-2 D-P001.svg This user abstains from
all forms of tobacco.
Coffee cup icon.svg This user limits caffeine consumption
to less than 500 mg per day.
Psychoactive Drugs.jpg This user is against the War on Drugs.
No Facebook.svg This user does not "Like" Facebook.
Nuvola apps emacs.png This user contributes using GNU/Linux, and disagrees with those who call it simply "Linux". Tux.svg
Free and open-source software logo (2009).svg This user supports free software.
FF This user thanks Richard Stallman and Creative Commons for letting Wikipedia become CC / GFDL dual licensed.
Free software logos This user uses
free software only.
Copyleft.svg This user prefers and supports Copyleft licensing.
PD-icon.svg This user is against DRM.
Demarchy.png This user abstains from voting.
Smiley in training.png This user is undergoing rigorous training.
Wikipedia-logo-v2.svg This user believes in the right of every human being to have access to Wikipedia.
Blue ribbon.svg This user is a member of Wikipedians against censorship.
Template icon This user is a template maker
Nuvola apps package toys svg.svg This user uses HotCat.
Penicillin core.svg This user contributes to the
Pharmacology WikiProject.
⚕ This user is a member of WikiProject Medicine.
Nuvola filesystems folder yellow.png This user is a member of WikiProject Categories.


Wiki Project Med Foundation logo.svg The Cure Award
In 2013 you were one of the top 300 medical editors across any language of Wikipedia. Thank you so much for helping bring free, complete, accurate, up-to-date medical information to the public. We really appreciate you and the vital work you do!

My contributions[edit]

Pages started[edit]


  1. 2011 Sangrampur methanol tragedy
  2. 25B-NBF
  3. 25C-NB3OMe
  4. 25C-NB4OMe
  5. 25C-NBF
  6. 25G-NBOMe
  7. 25H-NBOMe
  8. 25I-NB3OMe
  9. 25I-NB4OMe
  10. 25iP-NBOMe
  11. 3 A.M. Vodka
  12. College student alcoholism
  13. Comparison of web search engines
  14. Ledol
  15. Legality of Bitcoins by country
  16. List of amylase induced fermentations
  17. List of methanol poisoning incidents
  18. Long-term impact of alcohol on the brain
  19. Nihamanchi
  20. Parakaria
  21. PornMD
  22. XHamster


A depressogenic substance (or depressogen) is one that causes or can cause depression, usually as a side effect.[1] They are the functional opposites of antidepressants.[2]

Examples of drugs commonly associated with depressogenic effects include some anticonvulsants such as the barbiturates (e.g. phenobarbital), benzodiazepines (e.g. diazepam), vigabatrin, and topiramate, corticosteroids like dexamethasone and prednisone, cytokines like interferon-α and interleukin-2, certain antihypertensives such as amiodarone, clonidine, methyldopa, reserpine, and tetrabenazine (used as an antipsychotic/antihyperkinetic),[3][4] and agents with antiandrogen, antiestrogen, and/or anti-neurosteroid activities such as GnRH agonists (e.g., leuprolide, goserelin), anastrozole (an aromatase inhibitor), finasteride (a 5α-reductase inhibitor),[5] and clomiphene (a SERM), as well as others including flunarizine, mefloquine, and efavirenz.[1] Another notable agent is rimonabant, a cannabinoid receptor antagonist marketed as an anti-obesity agent which was withdrawn shortly after its introduction due to the incidence of severe psychiatric side effects associated with its use including depression, anxiety, and suicidal ideation.[6]

Examples of endogenous compounds that have been implicated in stress and depression include corticotropin-releasing hormone (CRH),[7][8] cytokines (e.g., interferon-α, interleukin-2),[9] tachykinins (e.g., substance P),[7] glucocorticoids (e.g., cortisol, cortisone),[7][8] and dynorphin.[10]

See also[edit]


  1. ^ a b Celano CM, Freudenreich O, Fernandez-Robles C, Stern TA, Caro MA, Huffman JC (2011). "Depressogenic effects of medications: a review". Dialogues in Clinical Neuroscience. 13 (1): 109–25. PMC 3181967Freely accessible. PMID 21485751. 
  2. ^ Belmaker RH (August 2008). "The future of depression psychopharmacology". CNS Spectrums. 13 (8): 682–7. PMID 18704023. 
  3. ^ Beers MH, Passman LJ (December 1990). "Antihypertensive medications and depression". Drugs. 40 (6): 792–9. PMID 2078996. doi:10.2165/00003495-199040060-00003. 
  4. ^ Kenney C, Hunter C, Mejia N, Jankovic J (2006). "Is history of depression a contraindication to treatment with tetrabenazine?". Clinical Neuropharmacology. 29 (5): 259–64. PMID 16960470. doi:10.1097/01.WNF.0000228369.25593.35. 
  5. ^ Finn DA, Beadles-Bohling AS, Beckley EH, et al. (2006). "A new look at the 5alpha-reductase inhibitor finasteride". CNS Drug Reviews. 12 (1): 53–76. PMID 16834758. doi:10.1111/j.1527-3458.2006.00053.x. 
  6. ^ Moreira FA, Crippa JA (June 2009). "The psychiatric side-effects of rimonabant". Revista Brasileira De Psiquiatria (São Paulo, Brazil : 1999). 31 (2): 145–53. PMID 19578688. doi:10.1590/s1516-44462009000200012. 
  7. ^ a b c Norman TR, Burrows GD (February 2007). "Emerging treatments for major depression". Expert Review of Neurotherapeutics. 7 (2): 203–13. PMID 17286553. doi:10.1586/14737175.7.2.203. 
  8. ^ a b Stokes PE, Sikes CR (February 1988). "The hypothalamic-pituitary-adrenocortical axis in major depression". Neurologic Clinics. 6 (1): 1–19. PMID 2837631. 
  9. ^ Gibb J, Audet MC, Hayley S, Anisman H (2009). "Neurochemical and behavioral responses to inflammatory immune stressors". Frontiers in Bioscience (Scholar Edition). 1: 275–95. PMID 19482702. doi:10.2741/e26. 
  10. ^ Knoll AT, Carlezon WA (February 2010). "Dynorphin, stress, and depression". Brain Research. 1314: 56–73. PMC 2819644Freely accessible. PMID 19782055. doi:10.1016/j.brainres.2009.09.074. 


Top edited articles[edit]

My top contributions.[1]

Top 10 by added text[edit]

Major improved articles[edit]

Article Before Useful state
Alcoholic beverage [2] [3]

Important edits[edit]
Article Revision links Edit summary Edit
Alcohol [4] Major copyedit Studies have found trace quantities of endogenous alcohols of healthy volunteers from exhaled breath with a mean of 450 ppb methanol[1] and 244 ppb ethanol.[2] The mean endogenous methanol in humans of 0.45 g/d may be metabolized from pectin found in fruit; One kilos of apple produces up to 1.4 gram methanol.[3] However, methanol should never consumed on its own as it is poisonous to the central nervous system, and may cause blindness, coma, and death. These studies are not guidelines that consumption of alcohol found in alcoholic beverages are healthy.
Cannabidiol [5][6][7] CBD does not induce the psychoactive high typically associated with recreational marijuana strains that are high in THC, not even in high doses.[4][5][6][7]
Cannabidiol [8] Hemp Industries Association said in 2014 that hemp seed oil is less than 25 parts per million CBD, thus hemp oil is not a source of CBD Which could be used in epilepsy treatments.[8]
Microchip implant (human) [9] Major copyedit

And it will cause all, the small and the great, and the poor, and the free and the bond to have a mark on their right hand or on their foreheads and it will bring it about that no one may be able to buy or sell, except him who has the mark, either the name of the beast or the number of its name.

— Apocalypse 13:16-17, Confraternity Edition Bible 1941
National Security Agency [10] Improved source Linus Torvalds, the founder of Linux kernel joked during a LinuxCon keynote 18 September 2013, that the NSA, who is the founder of SELinux, wanted a backdoor in the kernel.[9] However later, Linus father, Member of the European Parliament (MEP), revealed that the NSA actually did this.[10]

When my oldest son [Linus Torvalds] was asked the same question: “Has he been approached by the NSA about backdoors?” he said “No”, but at the same time he nodded. Then he was sort of in the legal free. He had given the right answer, [but] everybody understood that the NSA had approached him.

— Nils Torvalds, LIBE Committee Inquiry on Electronic Mass Surveillance of EU Citizens - 11th Hearing, 11 November 2013[11]
Richard Stallman [11][12] Major copyedit Stallman admire whistleblower Julian Assange[12], and Edward Snowden[13] who he advocate in hes email signature after Snowden leaked the PRISM scandal in 2013 that can be found in several mailing-lists:

To any NSA and FBI agents reading my email: please consider whether defending the US Constitution against all enemies, foreign or domestic, requires you to follow Snowden's example.

— Richard Stallman

Important articles[edit]

Drug research aimed to develop non-recreational drugs from typical recreational drugs.


  • User:Northamerica1000
    • This user has contributed to 27 Good Articles on Wikipedia.
    • This user has created 1,001 of the 5,390,134 articles on the English Language Wikipedia


User boxes[edit]

User page design center[edit]




Autoformat tool for citations[edit]

Please stop adding bare URLs to Wikipedia.

You will notice the autoformat tool for citations when you are in an edit window, that up at the top there is a toolbar. On the right, it says "Cite" and there is a little triangle next to it. If you click the triangle, another menu appears below. On the left side of the new menu bar, you will see "Templates". If you select (for example) "Cite journal", you can fill in the "doi" or the "PMID" field, and then if you click the little magnifying glass next to the field, the whole thing will auto-fill. Then you click the "insert" button at the bottom, and it will insert a ref like this (I changed the ref tags so it shows):

(ref) Huhtaniemi, I (2014). "Late-onset hypogonadism: current concepts and controversies of pathogenesis, diagnosis and treatment.". Asian journal of andrology. 16 (2): 192–202. PMID 24407185.  (/ref)

That takes about 10 seconds, if even that. As you can see there are templates for books, news, and websites, as well as journal articles, and each template has at least one field that you can use to autofill the rest. The autofill isn't perfect and I usually have to manually fix some things before I click "insert" but it generally works great and saves a bunch of time.

The PMID parameter is the one we care about the most on articles about health.

One thing the autofill doesn't do, is add the PMC field if it is there (PMC is a link to a free fulltext version of the article). you can add that after you insert the citation, or -- while you have the "cite journal" template open -- you can click the "show/hide extra fields" button at the bottom, and you will see the PMC field on the right, near the bottom. If you add the PMC number there that will be included, like this (again I have changed the ref tags):

(ref) Huhtaniemi, I (2014). "Late-onset hypogonadism: current concepts and controversies of pathogenesis, diagnosis and treatment.". Asian journal of andrology. 16 (2): 192–202. PMC 3955328Freely accessible. PMID 24407185.  (/ref)

The autofill also doesn't add the URL if there is a free fulltext that is not in PMC. You can add that manually too, after you autofill with PMID

  Thanks. Jytdog (talk) 04:17, 7 May 2017 (UTC)

This is a Wikipedia user page.

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Wikimedia Foundation
  1. ^
  2. ^
  3. ^
  4. ^ Grotenhermen, Franjo; Russo, Ethan; Zuardi, Antonio Waldo (1 January 2017). "Even High Doses of Oral Cannabidol Do Not Cause THC-Like Effects in Humans: Comment on Merrick et al. Cannabis and Cannabinoid Research 2016;1(1):102–112; DOI: 10.1089/can.2015.0004". Cannabis and Cannabinoid Research. 2 (1): 1–4. doi:10.1089/can.2016.0036. 
  5. ^ Kogan, NM; Melamed, E; Wasserman, E; Raphael, B; Breuer, A; Stok, KS; Sondergaard, R; Escudero, AV; Baraghithy, S; Attar-Namdar, M; Friedlander-Barenboim, S; Mathavan, N; Isaksson, H; Mechoulam, R; Müller, R; Bajayo, A; Gabet, Y; Bab, I (October 2015). "Cannabidiol, a Major Non-Psychotropic Cannabis Constituent Enhances Fracture Healing and Stimulates Lysyl Hydroxylase Activity in Osteoblasts.". Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 30 (10): 1905–13. PMID 25801536. 
  6. ^ Costa, B; Trovato, AE; Comelli, F; Giagnoni, G; Colleoni, M (5 February 2007). "The non-psychoactive cannabis constituent cannabidiol is an orally effective therapeutic agent in rat chronic inflammatory and neuropathic pain.". European journal of pharmacology. 556 (1-3): 75–83. PMID 17157290. 
  7. ^ Rimmerman, N; Juknat, A; Kozela, E; Levy, R; Bradshaw, HB; Vogel, Z (August 2011). "The non-psychoactive plant cannabinoid, cannabidiol affects cholesterol metabolism-related genes in microglial cells.". Cellular and molecular neurobiology. 31 (6): 921–30. PMID 21533611. 
  8. ^ Jones, Whitney. "Hemp Oil Not a Source of CBD Which Could Be Used in Epilepsy Treatments". 
  9. ^
  10. ^
  11. ^
  12. ^
  13. ^