WNT5B

WNT5B
Identifiers
Aliases	WNT5B, Wnt family member 5B
External IDs	OMIM: 606361; MGI: 98959; HomoloGene: 22530; GeneCards: WNT5B; OMA:WNT5B - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	1,647,212 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	119,521,308 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; periodontal fiber; ; prostate; ; muscle layer of sigmoid colon; ; minor salivary glands; ; palpebral conjunctiva; ; tibia; ; ventricular zone; ; olfactory zone of nasal mucosa; ; testicle;
	Top expressed in
	epithelium of lens; ; renal corpuscle; ; lamina propria of urethra; ; primitive streak; ; adventitia of seminal vesicle; ; aortic valve; ; adrenal medulla; ; internal carotid artery; ; vas deferens; ; conjunctival fornix;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	frizzled binding; signaling receptor binding;
Cellular component	endocytic vesicle membrane; endoplasmic reticulum lumen; plasma membrane; extracellular region; cell surface; Golgi lumen; extracellular exosome; extracellular space; extracellular matrix; collagen-containing extracellular matrix;
Biological process	cellular response to retinoic acid; cell fate commitment; chondrocyte differentiation; positive regulation of cell migration; wound healing; multicellular organism development; neuron differentiation; positive regulation of fat cell differentiation; fat cell differentiation; negative regulation of canonical Wnt signaling pathway; lens fiber cell development; Wnt signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	81029
	22419
	ENSG00000111186
	ENSMUSG00000030170
	Q9H1J7
	P22726
	NM_030775; NM_032642
	NM_001271757; NM_001271758; NM_009525
	NP_110402; NP_116031
	NP_001258686; NP_001258687; NP_033551
	Wikidata
View/Edit Human	View/Edit Mouse

Protein Wnt-5b is a protein that in humans is encoded by the WNT5B gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000111186 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000030170 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Saitoh T, Katoh M (Jul 2001). "Molecular cloning and characterization of human WNT5B on chromosome 12p13.3 region". Int J Oncol. 19 (2): 347–51. doi:10.3892/ijo.19.2.347. PMID 11445850.
^ Cite error: The named reference entrez was invoked but never defined (see the help page).

v t e Signaling pathway: Wnt signaling pathway
Ligand	WNT1 WNT2 WNT2B WNT3 WNT3A WNT4 WNT5A WNT5B WNT6 WNT7A WNT7B WNT8A WNT8B WNT9A WNT9B WNT10A WNT10B WNT11 WNT16
Receptor	Frizzled LRP5 LRP6
Second messenger	Dishevelled GSK-3 APC Beta-catenin

References

Further reading