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Symbol Nucleoporin
Pfam PF03177
InterPro IPR004870

The nucleoporins are a family of proteins which are the constituent building blocks of the nuclear pore complex.[1] The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the cell nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. Nuclear pores in turn allow the transport of water-soluble molecules across the nuclear envelope.

The proteins involved are named for their molecular weight (in kilo Daltons), and include the following:


  1. ^ Doye V, Hurt E (June 1997). "From nucleoporins to nuclear pore complexes". Curr. Opin. Cell Biol. 9 (3): 401–11. doi:10.1016/S0955-0674(97)80014-2. PMID 9159086. 

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