From Wikipedia, the free encyclopedia
Jump to: navigation, search
Skeletal formula of ozolinone
Space-filling model of oxolinone
Systematic (IUPAC) name
(2E)-[3-methyl-4-oxo-5-(piperidin-1-yl)-1,3-thiazolidin-2-ylidene]ethanoic acid
Clinical data
Legal status
  • Uncontrolled
Routes Oral
CAS number 56784-39-5
ATC code None
PubChem CID 6436036
ChemSpider 23253355
KEGG D05323
Chemical data
Formula C11H16N2O3S 
Mol. mass 256.32 g/mol

Ozolinone is a loop diuretic which was never marketed.[1][2][3]

It is an active metabolite of etozoline.[2]

See also[edit]


  1. ^ Dictionary of organic compounds. London: Chapman & Hall. 1996. ISBN 0-412-54090-8. 
  2. ^ a b Greven J, Heidenreich O (October 1978). "Effects of ozolinone, a diuretic active metabolite of etozoline, on renal function. I. Clearance studies in dogs". Naunyn-Schmiedeberg's Archives of Pharmacology 304 (3): 283–7. doi:10.1007/bf00507970. PMID 714186. 
  3. ^ Greven J, Beckers M, Defrain W, Meywald K, Heidenreich O (March 1980). "Studies with the optically active isomers of the new diuretic drug ozolinone. II. Inhibition by d-ozolinone of furosemide-induced diuresis". Pflügers Archiv : European Journal of Physiology 384 (1): 61–4. doi:10.1007/bf00589515. PMID 7189867.