Canrenone

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Canrenone
Canrenone.png
Systematic (IUPAC) name
10,13-dimethylspiro[2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthrene-17,5'-oxolane]-2',3-dione
Clinical data
Legal status ?
Pharmacokinetic data
Protein binding 95%
Half-life 10-35 hours
Identifiers
CAS number 976-71-6 N
ATC code C03DA03
PubChem CID 13789
ChemSpider 13192 YesY
UNII 78O20X9J0U YesY
ChEMBL CHEMBL1463345 N
Chemical data
Formula C22H28O3 
Mol. mass 340.456 g/mol
 N (what is this?)  (verify)

Canrenone (Contaren, Luvion) is an aldosterone antagonist with additional antiandrogen properties which is used as a diuretic in Europe.[1]

It is a major active metabolite of spironolactone, and is believed to be partially responsible for its effects.

See also[edit]

References[edit]

  1. ^ Romanelli RG, Gentilini P (May 2004). "Cross reactivity due to positive canrenone interference". Gut 53 (5): 772–3. PMC 1774040. PMID 15082604.