PIAS1

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Template:PBB E3 SUMO-protein ligase PIAS1 is an enzyme that in humans is encoded by the PIAS1 gene.[1][2][3]

Template:PBB Summary

Interactions

PIAS1 has been shown to interact with DNMT3A,[4] STAT1,[5] Small ubiquitin-related modifier 1,[6][7] Sp3 transcription factor,[8] UBE2I[6][7][8] and P53.[7][9]

References

  1. ^ Liu B, Liao J, Rao X, Kushner SA, Chung CD, Chang DD, Shuai K (September 1998). "Inhibition of Stat1-mediated gene activation by PIAS1". Proc Natl Acad Sci U S A. 95 (18): 10626–10631. doi:10.1073/pnas.95.18.10626. PMC 27945. PMID 9724754.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  2. ^ Valdez BC, Henning D, Perlaky L, Busch RK, Busch H (July 1997). "Cloning and characterization of Gu/RH-II binding protein". Biochem Biophys Res Commun. 234 (2): 335–340. doi:10.1006/bbrc.1997.6642. PMID 9177271.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  3. ^ "Entrez Gene: PIAS1 protein inhibitor of activated STAT, 1".
  4. ^ Ling, Yan (2004). "Modification of de novo DNA methyltransferase 3a (Dnmt3a) by SUMO-1 modulates its interaction with histone deacetylases (HDACs) and its capacity to repress transcription". Nucleic Acids Res. 32 (2). England: 598–610. doi:10.1093/nar/gkh195. PMC 373322. PMID 14752048. {{cite journal}}: Cite has empty unknown parameters: |laysummary=, |laydate=, and |laysource= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help)
  5. ^ Liao, J (May 2000). "Distinct roles of the NH2- and COOH-terminal domains of the protein inhibitor of activated signal transducer and activator of transcription (STAT) 1 (PIAS1) in cytokine-induced PIAS1-Stat1 interaction". Proc. Natl. Acad. Sci. U.S.A. 97 (10). UNITED STATES: 5267–5272. doi:10.1073/pnas.97.10.5267. ISSN 0027-8424. PMC 25817. PMID 10805787. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysummary=, and |laysource= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help)
  6. ^ a b Lee, Byoung-Hee (December 2003). "Association of the nucleocapsid protein of the Seoul and Hantaan hantaviruses with small ubiquitin-like modifier-1-related molecules". Virus Res. 98 (1). Netherlands: 83–91. doi:10.1016/j.virusres.2003.09.001. ISSN 0168-1702. PMID 14609633. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysummary=, and |laysource= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help)
  7. ^ a b c Kahyo, T (September 2001). "Involvement of PIAS1 in the sumoylation of tumor suppressor p53". Mol. Cell. 8 (3). United States: 713–718. doi:10.1016/S1097-2765(01)00349-5. ISSN 1097-2765. PMID 11583632. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysummary=, and |laysource= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help)
  8. ^ a b Sapetschnig, Alexandra (October 2002). "Transcription factor Sp3 is silenced through SUMO modification by PIAS1". EMBO J. 21 (19). England: 5206–5215. doi:10.1093/emboj/cdf510. ISSN 0261-4189. PMC 129032. PMID 12356736. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysummary=, and |laysource= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help)
  9. ^ Gallagher, W M (June 1999). "MBP1: a novel mutant p53-specific protein partner with oncogenic properties". Oncogene. 18 (24). ENGLAND: 3608–3616. doi:10.1038/sj.onc.1202937. ISSN 0950-9232. PMID 10380882. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysummary=, and |laysource= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help)

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