Portal vein thrombosis

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Portal vein thrombosis
Portal vein thrombosis in computertomography.
Classification and external resources
ICD-10 I81
ICD-9 452
eMedicine radio/571

Portal vein thrombosis, previously known as Cauchois–Eppinger–Frugoni syndrome,[1] is a form of venous thrombosis affecting the hepatic portal vein, which can lead to portal hypertension and reduction in the blood supply to the liver.

Signs and symptoms[edit]


Causes can include pancreatitis, cirrhosis, diverticulitis, and cholangiocarcinoma. It is also a known complication of splenectomy.[2]


The diagnosis of portal vein thrombosis is usually made by ultrasound, computed tomography with contrast or magnetic resonance imaging. D-dimer levels in the blood may be elevated as a result of fibrin degradation.


Portal vein thrombosis on computed tomography (left) and cavernous transformation of the portal vein after 1 year (right)

Treatments include anticoagulants, shunts, bypass surgery, and transplants.

See also[edit]


  1. ^ Strous, Rael D.; Edelman, Morris C. (2007). "Eponyms and the Nazi Era: Time to Remember and Time for Change". Israel Medical Association Journal 9: 207–214. 
  2. ^ Ali Cadili, Chris de Gara, "Complications of Splenectomy", The American Journal of Medicine, 2008, pp 371-375.

External links[edit]