Portal vein thrombosis is a form of venous thrombosis affecting the hepatic portal vein, which can lead to portal hypertension and reduction in the blood supply to the liver.
Signs and symptoms
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Causes can include pancreatitis, cirrhosis, diverticulitis, and cholangiocarcinoma. It is also a known complication of splenectomy.
The diagnosis of portal vein thrombosis is usually made by ultrasound, computed tomography with contrast or magnetic resonance imaging. D-dimer levels in the blood may be elevated as a result of fibrin degradation.
Portal vein thrombosis on computed tomography (left) and cavernous transformation of the portal vein after 1 year (right)
Treatments include anticoagulants, shunts, bypass surgery, and transplants.
- ^ Ali Cadili, Chris de Gara, "Complications of Splenectomy", The American Journal of Medicine, 2008, pp 371-375.