Pseudobulbar palsy
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| Pseudobulbar palsy | |
|---|---|
| Classification and external resources | |
| ICD-9 | 335.23 |
| DiseasesDB | 10826 |
| MeSH | D020828 |
Pseudobulbar palsy results from an upper motor neuron lesion to the corticobulbar pathways in the pyramidal tract. Patients have difficulty chewing, swallowing and demonstrate slurred speech (often initial presentation). Individuals with pseudobulbar palsy also demonstrate inappropriate emotional outbursts.
Contents |
[edit] Causes
- Vascular causes: Bilateral hemisphere infarction, CADASIL syndrome
- Progressive Supranuclear Palsy
- Amyotrophic lateral sclerosis (ALS)
- Parkinson's disease
- Multiple System Atrophy (related to Parkinson's disease)
- Degenerative disorders: motor neuron disease
- Inflammatory disorders: Multiple sclerosis
- Malignancy: High brain stem tumors
- Metabolic causes: osmotic demyelination syndrome[1]
- Brain trauma
[edit] Symptoms
These include:
- Dysphagia (difficulty in swallowing)
- Labile affect[2]
- Dysarthria
[edit] Signs
These include:
- Speech is slow, thick and indistinct
- Gag reflex is normal, exaggerated or absent
- Tongue is small, stiff and spastic
- Jaw jerk is brisk
- There may be upper motor neuron lesion of the limbs.
Bulbar palsy is a similar disorder but is caused by lower motor neuron lesions
[edit] See also
[edit] References
- ^ Bourgouin PM, Chalk C, Richardson J, Duang H, Vezina JL (Aug 1995). "Subcortical white matter lesions in osmotic demyelination syndrome". American Journal of Neuroradiology 16 (7): 1495–7. PMID 7484639.]
- ^ McCormick WE, Lee JH (May 2002). "Pseudobulbar palsy caused by a large petroclival meningioma: report of two cases". Skull Base 12 (2): 067–072. doi:10.1055/s-2002-31568-1. PMC 1656925. PMID 17167648. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1656925.
[edit] External links
- 248512525 at GPnotebook - "pseudobulbar palsy"
- 456458269 at GPnotebook - "comparison of bulbar and pseudobulbar palsy"
- eNotes
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